Results 181 to 190 of about 4,775,639 (287)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation. [PDF]

Front Nephrol
Heidenreich K, Goel D, Priyamvada PS, Kulkarni S, Chakurkar V, Khullar D, Singh R, Bale C, Zipfel PF.   +8 more
europepmc   +1 more source

AAPM Task Group 298: Recommendations on certificate program/alternative pathway candidate education and training. [PDF]

J Appl Clin Med Phys, 2022
Prisciandaro JI, Burmeister JW, DeLuca PM, Gerbi BJ, Giger ML, Robar JL, Seibert JA.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Correction: Sez6L2 inhibits complement by facilitating factor I cleavage of C3b and accelerating the decay of C3 convertases

Frontiers in Immunology
Wen Q. Qiu, Shaopeiwen Luo, Stefanie A. Ma, Priyanka Saminathan, Herman Li, Jenny M. Gunnersen, Harris A. Gelbard, Jennetta W. Hammond   +7 more
doaj   +1 more source

Pediatric Immunodeficiency Caused by Complement Classical and Alternative Pathway Defects Due to a Homozygous CFI Variant: A Case Report. [PDF]

Cureus
Wei J, Liu C, Tian M, Cao G, Li J.
europepmc   +1 more source

Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID-19. [PDF]

Immunology, 2023
Siggins MK, Davies K, Fellows R, Thwaites RS, Baillie JK, Semple MG, Openshaw PJM, Zelek WM, Harris CL, Morgan BP, ISARIC4C Investigators.   +10 more
europepmc   +1 more source

An alternate pathway for bilirubin catabolism

FEBS Letters, 1980
Kaul, Ravi, Kaul, Hari K., Krishna Murti, C.R.   +2 more
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Memorandum, Alternativen der Wirtschaftspolitik / Arbeitsgruppe "Alternative Wirtschaftspolitik"

MEMORANDUM, ALTERNATIVEN DER WIRTSCHAFTSPOLITIK / ARBEITSGRUPPE "ALTERNATIVE WIRTSCHAFTSPOLITIK" Memorandum / Arbeitsgruppe Alternative Wirtschaftpolitik (-) Memorandum, Alternativen der Wirtschaftspolitik / Arbeitsgruppe "Alternative ...
Arbeitsgruppe Alternative Wirtschaftspolitik
core   +1 more source