Results 201 to 210 of about 1,689,260 (355)

Expression of Properdin, the positive regulator of the Complement Alternative Pathway, at the fetal-maternal interface in Preeclampsia. [PDF]

Front Immunol
Yasmin H, Roy T, Agostinis C, Rao A, Sharma P, Toffoli M, Balduit A, Pegoraro S, Bindu S, Prasad R, Ricci G, Vatish M, Madan T, Bulla R, Kishore U.   +14 more
europepmc   +1 more source

Bacterial outer membrane vesicles provide an alternative pathway for trafficking of <i>Escherichia coli</i> O157 type III secreted effectors to epithelial cells. [PDF]

mSphere, 2023
Sirisaengtaksin N, O'Donoghue EJ, Jabbari S, Roe AJ, Krachler AM.   +4 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Complement Alternative Pathway Dominance in Atypical Hemolytic Uremic Syndrome Revealed by Endothelial Bioassays. [PDF]

Kidney Int Rep
Santarsiero D, Gastoldi S, Guaschino V, Bresin E, Pagani I, Pasini A, Romano E, Benigni A, Remuzzi G, Noris M, Aiello S.   +10 more
europepmc   +1 more source

The complement alternative pathway in paroxysmal nocturnal hemoglobinuria: From a pathogenic mechanism to a therapeutic target. [PDF]

Immunol Rev, 2023
Risitano AM, Frieri C, Urciuoli E, Marano L.   +3 more
europepmc   +1 more source

9. Adenovirus Vector Induced Immune Responses Are Dependent upon Multi-Faceted Interactions with Proteins of Both the Alternative and Classical Complement Pathways In Vivo [PDF]

, 2007

openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Alternative pathway-mediated tubular complement activation in human proteinuric kidney diseases: a proof-of-concept study. [PDF]

Clin Kidney J
Alkaff FF, Lammerts RGM, Tiller G, van den Heuvel MC, Bajema IM, Daha MR, van den Born J, Berger SP.   +7 more
europepmc   +1 more source

Genetic variability shapes the alternative pathway complement activity and predisposition to complement-related diseases. [PDF]

Immunol Rev, 2023
Rodríguez de Córdoba S.
europepmc   +1 more source

What is the evidence base for TIA clinics, and why might primary care be a better alternative care pathway for those with TIA presentation?

Tripdatabase
openalex   +1 more source