Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway. [PDF]
, 2008 BACKGROUND: Appropriately formulated quantitative computational models can support researchers in understanding the dynamic behaviour of biological pathways and support hypothesis formulation and selection by "in silico" experimentation.
A Herrmann +37 more
core +6 more sources
Complement factor H and the hemolytic uremic syndrome [PDF]
, 2007 Immune recognition is coupled to powerful proinflammatory effector pathways that must be tightly regulated. The ancient alternative pathway of complement activation is one such proinflammatory pathway.
Atkinson, John P, Goodship, Timothy H.J.
core +3 more sources
New alternative energy pathway for chemical pulp mills: from traditional fibers to methane production [PDF]
, 2017 Chemical pulp mills have a need to diversify their end-product portfolio due to the current changing bio-economy. In this study, the methane potential of brown, oxygen delignified and bleached pulp were evaluated in order to assess the potential of ...
Dahl Olli, Peka +3 more
core +2 more sources
Tribochemistry as an Alternative Synthesis Pathway [PDF]
Lubricants, 2020 While reactions driven by mechanical force or stress can be labeled mechanochemical, those specifically occurring at a sliding interface inherit the name tribochemical, which stems from the study of friction and wear: tribology. Increased perception of tribochemical reactions has been gained through technological advancement, and the development of new
Hayden Carlton +2 more
openaire +3 more sources
An alternative cytokinin biosynthesis pathway [PDF]
Proceedings of the National Academy of Sciences, 2000 Studies of de novo cytokinin biosynthesis in isopentenyltransferase ( ipt )-transformed Arabidopsis thaliana , involving in vivo deuterium labeling and mass spectrometry, showed that the biosynthetic rate of zeatinriboside-5′-monophosphate was
Nam-Hai Chua +7 more
openaire +3 more sources
A TRAF3-NIK module differentially regulates DNA vs RNA pathways in innate immune signaling. [PDF]
, 2018 Detection of viral genomes by the innate immune system elicits an antiviral gene program mediated by type I interferons (IFNs). While viral RNA and DNA species induce IFN via separate pathways, the mechanisms by which these pathways are differentially ...
Aliyari, Saba Roghiyh +9 more
core
Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. [PDF]
, 2020 Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C.
Filler, Scott G +7 more
core +3 more sources
Alternate pathways of cerebroside catabolism [PDF]
Lipids, 1973 AbstractA search was made for new degradative pathways for glucosyl and galactosyl ceramides in an effort to explain the failure of these lipids to accumulate in the brains of children with Krabbe's or Gaucher's disease. Using various buffers and incubation conditions, we tested brain homogenates from 12 day old rats with the stearate‐labeled and ...
Lin, Yuh‐nan, Radin, Norman S.
openaire +3 more sources
An Oncogenic Role for Alternative NF-κB Signaling in DLBCL Revealed upon Deregulated BCL6 Expression [PDF]
, 2009 SummaryDiffuse large B cell lymphoma (DLBCL) is a complex disease comprising diverse subtypes and genetic profiles. Possibly because of the prevalence of genetic alterations activating canonical NF-κB activity, a role for oncogenic lesions that activate ...
Alizadeh +48 more
core +3 more sources
Acute tubular necrosis is characterized by activation of the alternative pathway of complement [PDF]
, 2005 Acute tubular necrosis is characterized by activation of the alternative pathway of complement.BackgroundStudies in animal models have shown that the alternative pathway of complement is activated in the kidney after ischemia/reperfusion.
Ljubanovic, Danica +3 more
core +1 more source