Results 31 to 40 of about 782,609 (335)
Frontiers in Immunology, 2021 ObjectiveDysregulation of the complement system has been described in patients with heart failure (HF). However, data on the alternative pathway are scarce and it is unknown if levels of factor B (FB) and the C3 convertase C3bBbP are elevated in these ...
Margrethe Flesvig Holt +29 more
doaj +1 more source
Electronic transport in single-helical protein molecules: Effects of multiple charge conduction pathways and helical symmetry [PDF]
Physics Letters A 380, 2395 (2016), 2016 We propose a tight-binding model to investigate electronic transport properties of single helical protein molecules incorporating both the helical symmetry and the possibility of multiple charge transfer pathways. Our study reveals that due to existence of both the multiple charge transfer pathways and helical symmetry, the transport properties are ...
arxiv +1 more source
Pathway Realisability in Chemical Networks [PDF]
arXiv, 2023 The exploration of pathways and alternative pathways that have a specific function is of interest in numerous chemical contexts. A framework for specifying and searching for pathways has previously been developed, but a focus on which of the many pathway solutions are realisable, or can be made realisable, is missing.
arxiv
A machine learning approach to investigate regulatory control circuits in bacterial metabolic pathways [PDF]
, 2020 In this work, a machine learning approach for identifying the multi-omics metabolic regulatory control circuits inside the pathways is described. Therefore, the identification of bacterial metabolic pathways that are more regulated than others in term of their multi-omics follows from the analysis of these circuits .
arxiv +1 more source
Frontiers in Immunology, 2015 The complement system is a major constituent of the innate immune system. It not only bridges innate and adaptive arms of the immune system but also links the immune system with the coagulation system.
Hany Ibrahim Kenawy +2 more
doaj +1 more source
Learning to self-fold at a bifurcation [PDF]
, 2022 Disordered mechanical systems can deform along a network of pathways that branch and recombine at special configurations called bifurcation points. Multiple pathways are accessible from these bifurcation points; consequently, computer-aided design algorithms have been sought to achieve a specific structure of pathways at bifurcations by rationally ...
arxiv +1 more source
Dispensability of Escherichia coli's latent pathways [PDF]
Proc. Natl. Acad. Sci. USA 108, 3124-3129 (2011), 2011 Gene-knockout experiments on single-cell organisms have established that expression of a substantial fraction of genes is not needed for optimal growth. This problem acquired a new dimension with the recent discovery that environmental and genetic perturbations of the bacterium Escherichia coli are followed by the temporary activation of a large number
arxiv +1 more source
Frontiers in Immunology, 2021 The Sez6 family consists of Sez6, Sez6L, and Sez6L2. Its members are expressed throughout the brain and have been shown to influence synapse numbers and dendritic morphology. They are also linked to various neurological and psychiatric disorders.
Wen Q. Qiu +7 more
doaj +1 more source
The Role of Properdin in Killing of Non-Pathogenic Leptospira biflexa
Frontiers in Immunology, 2020 Properdin (P) is a positive regulatory protein that stabilizes the C3 convertase and C5 convertase of the complement alternative pathway (AP). Several studies have suggested that properdin can bind directly to the surface of certain pathogens regardless ...
Adriana Patricia Granados Martinez +7 more
doaj +1 more source
Proprotein Convertases and the Complement System
Frontiers in Immunology, 2022 Proteins destined for secretion - after removal of the signal sequence - often undergo further proteolytic processing by proprotein convertases (PCs).
József Dobó +3 more
doaj +1 more source