Results 61 to 70 of about 87,684,257 (245)
, 2023 This internet resource contains issues published throughout multiple years2023 Livestock Brand Renewal Window is Currently Open! -- New: Free Electronic CVI Available for Veterinarians -- Statewide FMD Exercise -- USDA Seeks Public Comment on Proposal to
Kansas Animal Health
core
LifeBackground: Animal studies remain fundamental to cardiovascular drug and device development, yet their ability to predict human responses is increasingly being questioned.
Rasit Dinc, Nurittin Ardic
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Repeatability of lameness, fear and slipping scores to assess animal welfare upon arrival in pig slaughterhouses [PDF]
, 2010 The EU project Welfare Quality (R) proposes an overall assessment system for animal welfare based on animal outcomes. The objective of this study was to test inter-observer reliability (IOR) when assessing lameness, fear and slipping and falling scores ...
Van Reenen, K. +23 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Animal Testing in Infectiology /
, 2001 Animal testing has a long history, and the resulting knowledge has brought about a significant contribution to the improvement of health and welfare of mankind and animals. Federal regulations concerning the performance of animal testing have become more
Schmidt, A.
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Journal of Animal Reproduction and BiotechnologyBackground: The small intestine plays a crucial role in animals in maintaining homeostasis as well as a series of physiological events such as nutrient uptake and immune function to improve productivity.
Bo Ram Lee +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source