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Curcumin ((1E,6E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) Induces Apoptosis-like Death in <i>Leishmania amazonensis</i> Promastigotes and Exhibits Leishmanicidal Activity in Infected Macrophages in Free and Beeswax-Based Nanoparticle Formulations. [PDF]
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Trypanosoma cruzi cell atlas as a single-cell resource for understanding parasite population heterogeneity and differentiation. [PDF]
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Different temperature requirements for intracellular growth of Leishmania spp. may account for the predominantly peripheral or visceral localization of the parasites in the vertebrate host. We show here that Leishmania mexicana amazonensis, an agent of cutaneous disease, is growth restricted in vitro at 37.5 C and viable at 34 C.
D, Biegel, G, Topper, M, Rabinovitch
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Leishmania amazonensis:The Phagocytosis of Amastigotes by Macrophages
Experimental Parasitology, 1998In the present study, we examine the cell biology of Leishmania amastigote uptake by mammalian cells and compare this process to the phagocytosis of IgG-opsonized erythrocytes. We report that many aspects of amastigote uptake into macrophages resemble classical receptor-mediated phagocytosis.
D C, Love, M, Mentink Kane, D M, Mosser
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