Results 61 to 70 of about 12,502 (214)

Modified Ridley’s Parasitic Index for quantification of Amastigote Load.

, 2016
Modified Ridley’s Parasitic Index for quantification of Amastigote Load.
Elie Alam (849772), Ibrahim Khalifeh (651096), Ossama Abbas (690200), Roger Moukarbel (849773)   +3 more
core   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Glycosylphosphatidylinositols are required for the development of Trypanosoma cruzi amastigotes [PDF]

Infection and Immunity, 1997
Induction of a glycosylphosphatidylinositol (GPI) deficiency in Trypanosoma cruzi by the heterologous expression of Trypanosoma brucei GPI-phospholipase C (GPI-PLC) results in decreased expression of major surface proteins (N. Garg, R. L. Tarleton, and K. Mensa-Wilmot, J. Biol. Chem. 272:12482-12491, 1997).
N, Garg, M, Postan, K, Mensa-Wilmot, R L, Tarleton   +3 more
openaire   +2 more sources

Cutaneous leishmaniosis in a dog vaccinated with LiESP/QA-21: effective or defective vaccine-related immune surveillance? A case report

Veterinární Medicína, 2017
Leishmania, an intracellular protozoan parasite, is endemic, widespread and represents a public health problem in most countries of the Mediterranean basin as it is implicated in a wide spectrum of diseases both in humans and animals.
A. de Cosmo, D. Mazzoni, A. Campanati, G.E. Magi, D. Beghelli   +4 more
doaj   +1 more source

Identification of Leishmania mexicana amastigote-specific genes and proteins

, 1999
The leishmaniases are parasitic human diseases that constitute a public health problem in many parts of the world. The diseases are caused by the protozoan Leishmania that as amastigotes are intracellular parasites of the host's macrophages.
Bellatin, Jaime Antonio
core   +1 more source

Modified Ridley's parasitic index for quantification of amastigote load.

, 2014
Modified Ridley's parasitic index for quantification of amastigote load.
Robert Habib (651092), Ibrahim Khalifeh (651096), Suad Taraif (651094), Asif Loya (651095), Khalil Charaffeddine (651093), Jessica Aoun (651091)   +5 more
core   +1 more source

Re-description of Trypanosoma corvi Stephens and Christophers,1908 Emend. Baker, 1976 and remarks on the Trypanosomes of the Avian Family Corvidae

Memorias do Instituto Oswaldo Cruz, 1994
The trypomastigote, epimastigote and amastigote stages of Trypanosoma corvi Stephens and Christophers, 1908 emend. Baker, 1976 from the peripheral blood, heart and bone marrow are described herein.
N. C. Nandi, Gordon F. Bennett
doaj   +1 more source

Administration of artinm lectin reduces the severity of the acute phase infection with Trypanosoma cruzi

FASEB BioAdvances, 2021
The acute phase of experimental Trypanosoma cruzi infection is associated with a strong inflammatory reaction, physiological changes, amastigote nests in tissues, and hematological alterations.
Camila Botelho Miguel, Thiago Aparecido da silva, Wellington Francisco Rodrigues, Patrícia Kellen Martins Oliveira‐Brito, Maria Cristina Roque‐Barreira, Javier Emílio Lazo‐Chica   +5 more
doaj   +1 more source

Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses

Exploration, Volume 6, Issue 4, August 2026.
Obesity‐linked hypercoagulation is driven by fibrinogen overproduction in a specific hepatocyte cluster via IL6 signalling. Genetic and mechanistic studies reveal this pathway as a key target for therapies to mitigate clotting risks and associated complications in obese individuals.
Shumin Li, Gengchen Feng, Xin Huang, Xiao Teng, Ziyi Yang, Yue Liu, Yonghui Jiang, Tao Zhu, Teng Liu, Yunfei Xu, Chang Pan, Han Zhao, Shaozhuang Liu, Shigang Zhao, Zi‐Jiang Chen   +14 more
wiley   +1 more source

Exploring Biological Properties of Manganese(II)‐Phenanthroline‐Based Complexes: In Vitro Insights

ChemistrySelect, Volume 11, Issue 29, 3 August 2026.
Four Mn(II) complexes with phenanthroline derivatives were studied. These compounds were tested against several parasites and different human cancer cells. Despite its cytotoxicity on breast cancer, DNA seems not to be the main biological target. These complexes can drive the design and development of new metal‐based agents with improved biological ...
Roberto S. Silva, Marcos V. Palmeira‐Mello, Mikaelly P. Caet, Celisnolia M. Leite, Arieli B. Portugal, Pedro H. Machado, Alexandre B. Carvalho, Isabel Correia, Leonardo M. Moreira, Thatiana L. B. V. Simão, Elena Lasunskaia, Michelle F. Muzitano, José L. Nepomuceno‐Silva, João L. M. Wanderley, Javier Ellena, Alzir A. Batista, Mario S. Schultz   +16 more
wiley   +1 more source