Results 71 to 80 of about 8,500 (184)

An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.

PLoS Neglected Tropical Diseases, 2012
Leishmaniasis is a tropical disease threatening 350 million people from endemic regions. The available drugs for treatment are inadequate, with limitations such as serious side effects, parasite resistance or high cost. Driven by this need for new drugs,
Jair L Siqueira-Neto, Seunghyun Moon, Jiyeon Jang, Gyongseon Yang, Changbok Lee, Hong Kee Moon, Eric Chatelain, Auguste Genovesio, Jonathan Cechetto, Lucio H Freitas-Junior   +9 more
doaj   +1 more source

Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction

Parasites & Vectors, 2015
Background Invasion of host cells by Trypanosoma cruzi extracellular amastigotes is host actin polymerization-dependent. However, the role of proteins related to actin dynamics during invasion by amastigotes remains to be investigated.
Thaise Lara Teixeira, Lilian Cruz, Renato Arruda Mortara, Claudio Vieira Da Silva   +3 more
doaj   +1 more source

Investigation and Comparison of Leishmania major Promastigote and Amastigote Protein Content by Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Leishmania is a protozoan of the trypanosomatidae family. This protozoan has two stages in its life cycle, promastigote form in sand flies and amastigote form in macrophage of mammalian hosts.
Simindokht Soleimanifard, Reza Arjmand, Seyyed Hosein Hejazi   +2 more
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Detection and counting of Leishmania intracellular parasites in microscopy images

Frontiers in Medical Technology
ProblemLeishmaniasis is a disease caused by protozoan parasites of the genus Leishmania and has a high prevalence and impact on global health. Currently, the available drugs for its treatment have drawbacks, such as high toxicity, resistance of the ...
Lariza María de la Caridad Portuondo-Mallet, Lariza María de la Caridad Portuondo-Mallet, Niurka Mollineda-Diogo, Rubén Orozco-Morales, Juan Valentín Lorenzo-Ginori   +4 more
doaj   +1 more source

CUTANEOUS LEISHMANIASIS: AN EXPERIENCE AT UMDC

Journal of University Medical & Dental College, 2014
: Leishmaniasis is caused by single-cell parasites of the genus Leishmania. More than 10 different Leishmania species can cause human diseases. The two main clinical manifestations of leishmaniasis are:  Visceral leishmaniasis  Cutaneous leishmaniasis ...
Tabinda Roheen, Tanzeela Rasheed, Shazia Aslam et al.   +2 more
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Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms

European Journal of Medicinal Chemistry Reports
Visceral leishmaniasis, the most severe form of the disease, is caused by L. donovani and L. infantum parasites; cutaneous leishmaniasis is the most common endemic form of leishmaniasis and mainly caused by L. tropica and L. major.
Gulsah Bayraktar, Pascal Marchand, Euzébio Guimarães Barbosa, Marilia Cecilia da Silva, Karen Cacilda Weber, Sandrine Cojean, Merve Saylam, Huseyin Istanbullu   +7 more
doaj   +1 more source

Amastigotes de Leishmania spp.

Revista Experiencia en Medicina del Hospital Regional Lambayeque, 2020
Cesar Alberto Cabrejos Montalvo, Katherine Erika Ipanaquè Muñoz   +1 more
openaire   +2 more sources

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity

Brazilian Journal of Medical and Biological Research, 2007
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpß1-3Galpa disaccharide.
A.K. Tanaka, P.A.J. Gorin, H.K. Takahashi, A.H. Straus   +3 more
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Visceral leishmaniasis: amastigotes in the bone marrow

Hematology, Transfusion and Cell Therapy, 2019
Noronha, Thiago Rodrigo de, Fock, Ricardo Ambrósio   +1 more
openaire   +2 more sources

Amastigotes forms of Trypanosoma cruzi detected in a renal allograft

Revista do Instituto de Medicina Tropical de São Paulo, 1997
Trypanosoma cruzi, the causative agent of Chagas?disease assumes two distinct forms in vertebrate hosts: circulating trypomastigote and tissular amastigote.
CARVALHO Maria Fernanda C., FRANCO Marcello F. de, SOARES Vitor Augusto   +2 more
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