Results 61 to 70 of about 11,756 (178)

Kinetoplastid membrane protein-11 is present in promastigotes and amastigotes of Leishmania amazonensis and its surface expression increases during metacyclogenesis

Memorias do Instituto Oswaldo Cruz, 2010
Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine.
Denise CS Matos, Lanuza AP Faccioli, Léa Cysne-Finkelstein, Paula Mello De Luca, Suzana Corte-Real, Geraldo RG Armôa, Elezer Monte Blanco Lemes, Débora Decote-Ricardo, Sergio CF Mendonça   +8 more
doaj   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro, Fernanda Nazaré Morgado, Renato Porrozzi   +2 more
wiley   +1 more source

Effects of Methanolic Extract of Arctium lappa Root on Promastigotes and Amastigotes of Leishmania major (in vitro)

Medical Laboratory Journal, 2016
Background and Objective: Leishmania major is a flagellate protozoan parasite causing cutaneous leishmaniasis. Although pentavalent antimony compounds are the first-line drugs for leishmaniasis, their application is often accompanied by numerous ...
Asghar Farghi Yamchi, Mansour Dabirzadeh, Abdolhossein Miri   +2 more
doaj  

Vector‐borne diseases‐knowledge maps

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA), Sofie Dhollander, Ieva Baltusyte, Fabio Bigoni, Alessandro Broglia, Jordi Figuerola, Hans‐Hermann Thulke, Miguel Angel Chueca Miranda   +7 more
wiley   +1 more source

Morphological comparison of axenic amastigogenesis of trypomastigotes and metacyclic forms of Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 2003
Amastigogenesis occurs first when metacyclic trypomastigotes from triatomine urine differentiate into amastigotes inside mammalian host cells and a secondary process when tissue-derived trypomastigotes invade new cells and differentiate newly to ...
María C Navarro, Ana R De Lima, José Askue, Víctor T Contreras   +3 more
doaj   +1 more source

Synthesis and evaluation of novel chromanone and quinolinone analogues of uniflorol as anti-leishmanial agents

Heliyon, 2020
Within this work, we describe the design and synthesis of a range of novel chromanones and quinolinones, based on natural products reported to possess anti-leishmanial action.
Helena Castro, Tânia Cruz, Patrícia de Aguiar Amaral, Paula da Silva Cardoso, Ahmed Alsaffar, Patrick Farrell, Ana M. Tomás, James W. Barlow   +7 more
doaj   +1 more source

Insulin-Like Growth Factor-I Induces Arginase Activity in Leishmania amazonensis Amastigote-Infected Macrophages through a Cytokine-Independent Mechanism

Mediators of Inflammation, 2014
Leishmania (Leishmania) amazonensis exhibits peculiarities in its interactions with hosts. Because amastigotes are the primary form associated with the progression of infection, we studied the effect of insulin-like growth factor (IGF)-I on interactions ...
Celia Maria Vieira Vendrame, Marcia Dias Teixeira Carvalho, Andre Gustavo Tempone, Hiro Goto   +3 more
doaj   +1 more source

CD4+ T Cell-Dependent Macrophage Activation Modulates Sustained PS Exposure on Intracellular Amastigotes of Leishmania amazonensis

Frontiers in Cellular and Infection Microbiology, 2019
Leishmania amazonensis amastigotes can make use of surface-exposed phosphatidylserine (PS) molecules to promote infection and non-classical activation of macrophages (MΦ), leading to uncontrolled intracellular proliferation of the parasites.
Joao Luiz Mendes Wanderley, Poliana Deolindo, Eric Carlsen, Arieli Bernardo Portugal, Renato Augusto DaMatta, Marcello Andre Barcinski, Lynn Soong   +6 more
doaj   +1 more source

Atomic Force Microscopy of host cell-amastigote interaction in cutaneous leishmaniasis

Kasmera, 2004
: Natural infection produced by the entry of promastigotes into the skin cells induces cutaneous leishmaniasis disease and the Interaction between phagocytic cells and different strains of Leishmania determine the course of disease in the mammalian host.
Lugo de Yarbuh A, Colasante C, Alarcón M, Moreno E   +3 more
doaj  

Cytotoxic Effect of Methanolic Extract of Terminalia chebula Retz Fruit on the Leishmania Major In vitro

Journal of Medicinal Plants, 2016
Background: Cutaneous leishmaniasis is one of major public health problem in many countries. Pentavalent antimonite components as first line treatment of cutaneous leishmaniasis has many limitations and side effects.
H Noormohammadi, Y Maroufi, M Dabirzadeh, AH Miri, A Geraili   +4 more
doaj