Results 21 to 30 of about 15,918,440 (250)

From transglutaminases (TGs) to arylamine N-acetyltransferases (NATs): Insight into the role of a spatially conserved aromatic amino acid position in the active site of these two families of enzymes

Biochemical and Biophysical Research Communications, 2020
Transglutaminases (TG) and arylamine N-acetyltransferases (NAT) are important family of enzymes. Although they catalyze different reactions and have distinct structures, these two families of enzymes share a spatially conserved catalytic triad (Cys, His, Asp residues).
Xu, Ximing, Zhang, Wenchao, Berthelet, Jeremy, Liu, Rongxing, Michail, Christina, Chaffotte, Alain F., Dupret, Jean-Marie, Rodrigues-Lima, Fernando   +7 more
openaire   +4 more sources

Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages [PDF]

, 2012
Latent M. tuberculosis infection presents one of the major obstacles in the global eradication of tuberculosis (TB). Cholesterol plays a critical role in the persistence of M. tuberculosis within the macrophage during latent infection.
Russell, AJ, Edith Sim, Staunton, D, Angela J Russell, Staunton David, Russell Angela J., Areej Abuhammad (106459), Staunton, David, Westwood, IM, Stephen G Davies, Seden Peter T., Elizabeth Fullam (106463), Davies, Stephen G, Bhakta, Sanjib, Lowe, Edward D., Sim, Edith, David Staunton, Edward D. Lowe (106466), Akane Kawamura (50084), Seden, PT, Lowe, ED, Sim, E, Fullam Elizabeth, Fullam, Elizabeth, Garman, Elspeth F., Abuhammad Areej, Russell, Angela J, David L Wilson, Westwood Isaac M., Elspeth F Garman, Abuhammad, Areej, Davies, Stephen G., Davies, Stephen, Garman Elspeth F., Garman, Elspeth, Seden, Peter T, Kawamura, A, Sanjib Bhakta (106475), Elspeth F. Garman (106483), Fullam, E, Bhakta, S, Westwood, Isaac M, Garner, Alun Christopher, Russell, Angela J., Lowe Edward D., Garner, AC, Isaac M Westwood, Kawamura Akane, Bhakta Sanjib, Westwood, Isaac, Garner Alun Christopher, Akane Kawamura, Alun Christopher Garner (106477), Seden, Peter T., Alun Christopher Garner, Kawamura, Akane, Abuhammad, A, Elizabeth Fullam, Lowe, Edward D, Isaac M. Westwood (106473), David L. Wilson (74373), Angela J. Russell (106482), Wilson, DL, Davies, SG, Edward D Lowe, Wilson, David L., Peter T. Seden (106479), Wilson, David L, Sanjib Bhakta, Peter T Seden, Davies Stephen G., Garman, EF, Edith Sim (50087), Wilson David L., Stephen G. Davies (106481), Areej Abuhammad, David Staunton (106470), Garman, Elspeth F, Sim Edith   +78 more
core   +2 more sources

Polymorphism and mutational diversity of virulence (vcgCPI/vcgCPE) and resistance determinants (aac(3)-IIa, (aacC2, strA, Sul 1, and 11) among human pathogenic Vibrio species recovered from surface waters in South-Western districts of Uganda

Journal of Genetic Engineering and Biotechnology, 2023
Background Vibrio species are among the autochthonous bacterial  populations found in surface waters and associated with various life-threatening extraintestinal diseases, especially in human populations with underlying illnesses and wound infections ...
Hope Onohuean, Uchechukwu U. Nwodo
doaj   +1 more source

Prediction of reaction knockouts to maximize succinate production by Actinobacillus succinogenes. [PDF]

PLoS ONE, 2018
Succinate is a precursor of multiple commodity chemicals and bio-based succinate production is an active area of industrial bioengineering research. One of the most important microbial strains for bio-based production of succinate is the capnophilic gram-
Ambarish Nag, Peter C St John, Michael F Crowley, Yannick J Bomble   +3 more
doaj   +1 more source

Effects of bioactive molecules on the concentration of biogenic amines in foods and biological systems

Heliyon, 2022
Biogenic amines (BAs) are a group of molecules naturally present in foods that contain amino acids, peptides, and proteins as well as in biological systems.
Patrick Blondin Tsafack, Apollinaire Tsopmo   +1 more
doaj   +1 more source

Simultaneous Suppression of Two Distinct Serotonin N-Acetyltransferase Isogenes by RNA Interference Leads to Severe Decreases in Melatonin and Accelerated Seed Deterioration in Rice

Biomolecules, 2020
Serotonin N-acetyltransferase (SNAT) is the penultimate enzyme in the melatonin biosynthetic pathway, in which serotonin is converted into N-acetylserotonin (NAS) in plants.
Ok Jin Hwang, Kyoungwhan Back
doaj   +1 more source

Exploring regulation genes involved in the expression of L-amino acid oxidase in Pseudoalteromonas sp. Rf-1. [PDF]

PLoS ONE, 2015
Bacterial L-amino acid oxidase (LAAO) is believed to play important biological and ecological roles in marine niches, thus attracting increasing attention to understand the regulation mechanisms underlying its production.
Zhiliang Yu, Ju Wang, Jianxun Lin, Minyan Zhao, Juanping Qiu   +4 more
doaj   +1 more source

Root phloem-specific expression of the plasma membrane amino acid proton co-transporter AAP3 [PDF]

, 2004
Amino acids are regarded as the nitrogen ‘currency’ of plants. Amino acids can be taken up from the soil directly or synthesized from inorganic nitrogen, and then circulated in the plant via phloem and xylem.
Sakiko Okumoto, Leister, D., Frommer, Wolf B., Wolf B. Frommer, Okumoto, Sakiko, FISCHER, Wolf N, Stierhof, York Dieter, Frommer, W. B., Stierhof, Y., Stierhof, Y.-D., Fischer, W., Wolfgang Koch, Koch, W., FROMMER, Wolf B, Mechthild Tegeder, Fischer, Wolf N., Leister, Dario, Wolf N. Fischer, Koch, Wolfgang, Okumoto, S., Tegeder, Mechthild, Dario Leister, Tegeder, M., Biehl, A., York Dieter Stierhof, Alexander Biehl, Biehl, Alexander, Fischer, W. N., Frommer, W.   +28 more
core   +2 more sources

Arylamine N-acetyltransferase from chicken liver. I. Monoclonal antibodies, immunoaffinity purification, and amino acid sequences.

Journal of Biological Chemistry, 1988
Five monoclonal antibodies against arylamine acetyltransferase (EC 2.3.1.5) from the chicken liver were established by immunizing a mouse with a partially purified enzyme preparation. None of the antibodies cross-reacted with arylamine N-acetyltransferase from the livers of cow, rabbit, and rat, nor with arylalkylamine N-acetyltransferase from the ...
T, Deguchi, Y, Sakamoto, Y, Sasaki, K, Uyemura   +3 more
openaire   +2 more sources

Differential thermal stability, conformational stability and unfolding behavior of Eis proteins from Mycobacterium smegmatis and Mycobacterium tuberculosis.

PLoS ONE, 2019
Eis (Enhanced Intracellular Survival) is an important aminoglycoside N-acetyltransferase enzyme contributing to kanamycin resistance in Mtb clinical isolates. Eis proteins from M. tuberculosis (RvEis) and M.
Shashi Anand, Arsheed Ahmad Ganaie, Charu Sharma   +2 more
doaj   +1 more source