Results 131 to 140 of about 8,038 (247)

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Modified prokaryotic glucose isomerase enzymes with altered pH activity profiles

, 1994
A method for selecting amino acid residues is disclosed which upon replacement will give rise to an enzyme with an altered pH optimum. The method is specific for metalloenzymes which are inactivated at low pH due to the dissociation of the metal ions ...
Misset, Onno, Quax, Wim; id_orcid, Lambeir, Anne-Marie, Mrabet, Nadir, Lasters, Ignace, Van Der Laan, Jan M.   +5 more
core   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Microbial Oxidative Stress in Food Fermentations: A Comprehensive Review

eFood, Volume 7, Issue 4, August 2026.
Oxidative stress has a dual role in food fermentations: low ROS supports adaptive signaling, whereas excessive ROS causes cellular damage and process inhibition. Managing redox state as a controllable process variable can improve fermentation robustness and final food quality.
Wanrong Hu, Manxi Wu, Hui Xu, Jiebiao Chen, Wen Cai, Han Yang, Hujing Cao, Xinlin Huang, Jinping Cao, Chongde Sun, Yue Wang, Dongliang Li   +11 more
wiley   +1 more source

A Novel Epimerase Catalyzing Multiple Isomerization of Amino Acid Residues of Ribosomal Peptide

Salinipeptins, grisemycin, and cypemycin are ribosomally synthesized and post-translationally modified peptides (RiPPs). Among these, salinipeptins were reported to comprise 22 amino acid residues with multiple D-amino acids, and its biosynthetic gene ...
Xiao, Wanlu
core  

Protein Folding Problem

, 2003
Mechanisms by which the amino acid sequence of polypeptide chains determines their three-dimensional conformation. Topics include: sequence determinants of secondary structure; folding of newly synthesized polypeptide chains within cells; unfolding and ...
King, Jonathan, 1941-, Gossard, D.
core  

Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomerase. [PDF]

Protein Sci
DeVoe SC, Yost TC, Newton AJ, Grever GA, Ayala MF, Griffith WP, Latvala RD, Schmidpeter PAM.   +7 more
europepmc   +1 more source

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun, Nicole Hammann, Lina Leghlam, Bianca Peters, Cigdem Arikan, Sarah M. Bedoyan, Qian Chen, Tal Dattner, Felix Distelmaier, Alexander Fichtner, Sven F. Garbade, Nedim Hadžić, Robert Hegarty, Andrea Hellwig, Marianne Hørby Jørgensen, Carolin Jentsch, Sabine Jung‐Klawitter, Martin Laass, Elke Lainka, Hannah Münch, Halise Neslihan Önenli Mungan, Moritz Niesert, Stephanie Oehrl, Begona Polo, Knut Schäkel, James E. Squires, Stefan Kölker, Georg F. Hoffmann, Christian Staufner, Dominic Lenz   +29 more
wiley   +1 more source

Molecular evolution and diversity of isomerase-reductase clusters involved in the bacterial metabolism of glycosaminoglycans. [PDF]

mSphere
Nishimura Y, Okumura K, Oiki S, Ogura K, Hashimoto W.   +4 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, Volume 16, Issue 7, Page 1340-1357, July 2026.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source