Results 141 to 150 of about 8,038 (247)

RNA polymerase II: the elephant in the room. [PDF]

Trends Genet
Henikoff S, Hahn S.
europepmc   +1 more source

Remodelling the tumour microenvironment and beyond: ERO1A as a multifaceted regulator and emerging therapeutic target in cancer

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
ERO1A exhibits oncogenic functions, including promoting tumour progression, metastasis, epithelial‒mesenchymal transition, angiogenesis, immune evasion and metabolic reprogramming. ERO1A is also identified as a diagnostic biomarker and a factor contributing to therapy resistance (chemotherapy and immunotherapy).
Jing Mao, Kai Wang
wiley   +1 more source

Logical Exploration of Cinnamoyl-Containing Nonribosomal Peptides via Metabologenomic Targeting and Regulator Overexpression. [PDF]

J Am Chem Soc
Kang S, Huynh TH, Kim JM, Heo BE, Jang SC, Ock CW, Lee J, Song Y, An JS, Shen B, Kim SB, Jang J, Lee SK, Yoon YJ, Oh DC.   +14 more
europepmc   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source

Thiol Isomerases: Enzymatic Mechanisms, Models of Oxidation, and Antagonism by Galloylated Polyphenols. [PDF]

Antioxidants (Basel)
Owegie OC, Kennedy QP, Davizon-Castillo P, Yang M.   +3 more
europepmc   +1 more source

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu, Hanjing Wu, Brendan Holland, Colin J. Barrow, Hafiz A. R. Suleria   +4 more
wiley   +1 more source

A monoclonal antibody to platelet αIIbβ3 that inhibits protein disulfide isomerase binding and platelet aggregation. [PDF]

Blood Adv
Wang L, Wang J, Li J, Coller BS.
europepmc   +1 more source

Insights Into the Regulation of Salt Tolerance by Flavonoid and Cyanoamino Acid Metabolism in Sorghum‐Sudangrass Hybrids

Plant Direct, Volume 10, Issue 7, July 2026.
ABSTRACT Clarifying the molecular mechanisms underlying salt tolerance in high‐performing sorghum‐sudangrass hybrids can aid the identification of salt tolerance genes. Here, the previously screened salt‐tolerant sorghum‐sudangrass hybrid variety MN9 and the salt‐sensitive variety MN4 were grown in sand‐filled pots.
Yue Shi, Zili Liu, Shuancheng Liu, Wenjuan Chai, Junxiang Mu   +4 more
wiley   +1 more source

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, Volume 26, Issue 7, Page 69-83, July 2026.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Novel chemistry and structural perspectives in vitamin B₁₂-dependent radical SAM enzymes. [PDF]

Chem Sci
Berteau O, Teixeira Nunes M, Taraglio N, Legrand P, Benjdia A.   +4 more
europepmc   +1 more source