Results 141 to 150 of about 13,885 (249)

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

PROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor, Austin Lipinski, Paul R. Langlais, Jacob C. Schwartz   +3 more
wiley   +1 more source

Oxidized PDI promotes thrombus formation in oxidative stress. [PDF]

Blood
Yang M, Owegie OC, Patel A, Kennedy QP, Flaumenhaft JT, Chinnaraj M, Ponzar N, Fulcidor EM, Rico MC, Bhowmik A, Carroll KS, Handy DE, Loscalzo J, Essex DW, Pozzi N, Flaumenhaft R.   +15 more
europepmc   +1 more source

Medium- and short-chain dehydrogenase/reductase gene and protein families [PDF]

, 2008

core   +1 more source

Hydrophobic interactions of a substrate with L193 on the flexible substrate‐binding loop contribute to 3α‐hydroxysteroid dehydrogenase/carbonyl reductase catalytic efficiency

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Flexible loops within enzyme active sites are central to substrate binding, transition‐state stabilization, and catalytic turnover. Hydrophobic interactions modulate ligand recognition and influence protein function. Here, we interrogated loop‐mediated hydrophobic contributions to catalysis in 3α‐hydroxysteroid dehydrogenase/carbonyl reductase
Yan‐Liang Chen, Yun‐Hao Chou, Hwei‐Jen Lee, Tzu‐Pin Wang, Chi‐Ching Hwang   +4 more
wiley   +1 more source

Allosteric Disulfide Bridges in Integrins: The Molecular Switches of Redox Regulation of Integrin-Mediated Cell Functions. [PDF]

Antioxidants (Basel)
Eble JA.
europepmc   +1 more source

Functional shifts of the dual-substrate phosphoribosyl isomerase PriA from primary to specialized metabolism in rare Actinomycetota. [PDF]

Microb Genom
Rosas-Becerra LR, Arredondo-Cruz A, Sélem-Mojica N, Barona-Gómez F.   +3 more
europepmc   +1 more source

Conkazal‐M1 from the MKAVA family of conotoxins: A dual‐function protease inhibitor and neuroactive peptide

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Matías Leonel Giglio, Samuel S. Espino, Zildjian G. Acyatan, Maren Watkins, Baldomero M. Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +12 more
wiley   +1 more source

Recent advances in vascular thiol isomerases: insights into structures, functions in thrombosis and antithrombotic inhibitor development. [PDF]

Thromb J
Jiang L, Yuan C, Flaumenhaft R, Huang M.
europepmc   +1 more source

Serum Proteomic Analysis Using Gel‐Based Liquid Chromatography Tandem Mass Spectrometry Reveals Differences Between Canine Oral Malignancies and Non‐Malignant Conditions

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study establishes a GeLC‐MS/MS‐based serum proteomics workflow for canine oral oncology to differentiate malignancies from non‐malignant conditions. Comprehensive protein profiling, pathway analysis and protein–drug interaction mapping reveal candidate biomarkers and insights into the pathogenesis of canine oral cancers.
Sekkarin Ploypetch, Sittiruk Roytrakul, Janthima Jaresitthikunchai, Narumon Phaonakrop, Gunnaporn Suriyaphol   +4 more
wiley   +1 more source

Catalyzing Protein Folding by Chaperones. [PDF]

Biology (Basel)
Huang Z, Horowitz S.
europepmc   +1 more source