Results 11 to 20 of about 363,714 (297)

Myricetin Amorphous Solid Dispersions—Antineurodegenerative Potential [PDF]

Molecules
Our research aimed to develop an amorphous solid dispersion (ASD) of myricetin (MYR) with Polyvinylpyrrolidone K30 (PVP30) to enhance its solubility, dissolution rate, antioxidant, and neuroprotective properties.
Natalia Rosiak, Ewa Tykarska, Judyta Cielecka-Piontek   +2 more
doaj   +4 more sources

Solubility and Physical Stability Enhancement of Loratadine by Preparation of Co-Amorphous Solid Dispersion with Chlorpheniramine and Polyvinylpyrrolidone

Pharmaceutics, 2023
Loratadine (LRD), a non-sedating and slow-acting antihistamine, is often given in combination with short-onset chlorpheniramine maleate (CPM) to increase efficacy. However, LRD has poor water solubility resulting in low bioavailability.
Krit Suknuntha, Nattakanwadee Khumpirapang, Vimon Tantishaiyakul, Siriporn Okonogi   +3 more
doaj   +1 more source

A family of oxychloride amorphous solid electrolytes for long-cycling all-solid-state lithium batteries

Nature Communications, 2023
Solid electrolyte is vital to ensure all-solid-state batteries with improved safety, long cyclability, and feasibility at different temperatures. Herein, we report a new family of amorphous solid electrolytes, xLi2O-MCly (M = Ta or Hf, 0.8 ≤ x ≤ 2, y = 5
Shumin Zhang, Feipeng Zhao, Jiatang Chen, Jiamin Fu, Jing Luo, Sandamini H. Alahakoon, Lo-Yueh Chang, Renfei Feng, Mohsen Shakouri, Jianwen Liang, Yang Zhao, Xiaona Li, Le He, Yining Huang, Tsun-Kong Sham, Xueliang Sun   +15 more
doaj   +1 more source

Towards quantitative determination of atomic structures of amorphous materials in three dimensions

National Science Open, 2023
Amorphous materials such as glass, polymer and amorphous alloy have broad applications ranging from daily life to extreme conditions due to their unique properties in elasticity, strength and electrical resistivity.
Xie Zhiheng, Zhang Yao, Huang Siwei, Li Zezhou, Cheng Qi, Zhou Jihan   +5 more
doaj   +1 more source

Generalization of the Hall-Petch and inverse Hall-Petch behaviors by tuning amorphous regions in 2D solids

National Science Open, 2023
The strength $ σ_{y}(D)$ of a polycrystal can decrease or increase with the grain diameter $D$, i.e., the famous Hall-Petch (HP) and inverse-Hall-Petch (IHP) behaviors, respectively.
Xu Zhibin, Li Mengmeng, Zhang Huijun, Han Yilong   +3 more
doaj   +1 more source

Optimization of amorphous solid dispersion techniques to enhance solubility of febuxostat [PDF]

Folia Medica, 2021
Febuxostat is a selective inhibitor of xanthine oxidase and belongs to BCS class II drugs having low solubility and high permeability. Solubility is the most important parameter which directly affects dissolution, absorption and bioavailability of the ...
Vaishali P. Patel, Anita P. Patel, Ashish Shah   +2 more
doaj   +3 more sources

Emergent Elasticity in Amorphous Solids [PDF]

Physical Review Letters, 2020
6 Pages, 3 Figures + Supplementary ...
Jishnu N. Nampoothiri, Yinqiao Wang, Kabir Ramola, Jie Zhang, Subhro Bhattacharjee, Bulbul Chakraborty   +5 more
openaire   +3 more sources

The combination of hydroxypropylmethylcellulose acetate succinate and L-lysine into ternary amorphous solid dispersions of quercetin to enhance its dissolution

Carbohydrate Polymer Technologies and Applications, 2021
The purpose of this study was to enhance quercetin (Que) dissolution by preparing its ternary amorphous solid dispersions. The ternary amorphous solid dispersions were prepared by solvent evaporation method using hydroxypropylmethylcellulose acetate ...
Yiru Wang, Wenrong Qin, Qi Liang, Feng Zhou, Chengyun Yan, Yueyi Deng   +5 more
doaj   +1 more source

Cavitation in Amorphous Solids [PDF]

Physical Review Letters, 2013
Molecular dynamics simulations of cavitation in a Zr(50)Cu(50) metallic glass exhibit a waiting time dependent cavitation rate. On short time scales nucleation rates and critical cavity sizes are commensurate with a classical theory of nucleation that accounts for both the plastic dissipation during cavitation and the cavity size dependence of the ...
Pengfei, Guan, Shuo, Lu, Michael J B, Spector, Pavan K, Valavala, Michael L, Falk   +4 more
openaire   +2 more sources

Amorphous Solid Dispersions: Role of the Polymer and Its Importance in Physical Stability and In Vitro Performance

Pharmaceutics, 2022
Amorphous solid dispersions stabilized by one or more polymer(s) have been widely used for delivering amorphous drugs with poor water solubilities, and they have gained great market success.
Qin Shi, Haibiao Chen, Yanan Wang, Ruoxun Wang, Jia Xu, Chen Zhang   +5 more
doaj   +1 more source