Results 101 to 110 of about 168,658 (234)

人Kunitz型蛋白酶抑制剂-KD/APP的研究进展

Zhongguo shiyan zhenduanxue, 2013
牛胰蛋白酶抑制剂（Bovine pancreatic trypsin inhibitor,BPTI）具用广泛的蛋白酶抑制活性。但BPTI是一种异源性蛋白质,具有抗原性。淀粉样β蛋白前体（amyloid beta-pro-tein precursor,APP）中的Kunitz型蛋白酶抑制剂结构域(Kunitz protease inhibitor domain of amyloid protein precur-
孟威宏, 王虹蛟, 王强, 颜炜群
doaj  

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.

Science, 1999
R. Vassar, B. Bennett, S. Babu-Khan, S. Kahn, E. A. Mendiaz, P. Denis, D. Teplow, Sandra L. Ross, P. Amarante, R. Loeloff, Yi Luo, S. Fisher, J. Fuller, S. Edenson, J. Lile, M. Jarosinski, A. Biere, E. Curran, T. Burgess, J. Louis, F. Collins, J. Treanor, Gary Rogers, M. Citron   +23 more
semanticscholar   +1 more source

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus.

Proceedings of the National Academy of Sciences of the United States of America, 1993
C. Heurteaux, V. Bertaina, C. Widmann, M. Lazdunski   +3 more
semanticscholar   +1 more source

Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins [PDF]

, 2017
Agosta, Alata, Albert A. Davis, Aleshkov, Allen, Alzheimer, Anderson, Atagi, Bailey, Bales, Bales, Bales, Basak, Bateman, Beffert, Beffert, Beffert, Bell, Bell, Benilova, Benjamin, Bernardi, Bertram, Bien-Ly, Bien-Ly, Biere, Brecht, Brunden, Bu, Caselli, Castellano, Castellano, Cedazo-Mínguez, Cheng, Cirrito, Cirrito, Cole, Cooper, Corder, Corder, Cotman, David M. Holtzman, de la Torre, Deane, Deane, DeMattos, Drory, Emamzadeh, Engelborghs, Esparza, Evans, Fabre, Fagan, Fagan, Farrer, Fryer, Fryer, Funato, Gallardo, Gallyas, Games, Gao, Garai, Govone, Greenberg, Grehan, Guerreiro, Gustafson, Halliday, Hardy, Harris, Harris, Heinonen, Hirsch-Reinshagen, Hirsch-Reinshagen, Holtzman, Holtzman, Holtzman, Holtzman, Hone, Hong, Hu, Huang, Huang, Huang, Hughes, Irizarry, Irwin, Irwin, Irwin, Iwai, Jakes, Jarrett, Jason D. Ulrich, Jellinger, Ji, Jiang, Jonsson, Josephs, Kanekiyo, Kehoe, Kim, Kim, Kim, Klunk, Klunk, Koistinaho, Koldamova, Korczyn, Kotzbauer, Lacomblez, LaDu, LaDu, Lashuel, Lee, Li, Li, Li, Li, Liao, Lill, Lippa, Liu, Liu, Ma, Mahley, Mahley, Mak, Mandrekar, Marchesi, Marder, Martin, Masliah, Mathis, Mattila, Mauch, McKee, Mikolaenko, Morris, Mui, Nalivaeva, Namba, Narita, Nathan, Nelson, Nielsen, Ohm, Panegyres, Paresce, Paresce, Pfeifer, Pfrieger, Pitas, Poirier, Praline, Rebeck, Rebeck, Reiman, Riemenschneider, Rockenstein, Roses, Roychaudhuri, Saavedra, Sabbagh, Saito, Sanan, Schmechel, Shaffer, Shibata, Siderowf, Srinivasan, Strittmatter, Strittmatter, Strittmatter, Sullivan, Sunderland, Szaruga, Tamamizu-Kato, Tesseur, Thal, Theendakara, Tien-Phat V. Huynh, Tiraboschi, Tokuda, Tsuang, Ulrich, Van Gool, van Horssen, Verghese, Wahrle, Wahrle, Wakabayashi, Wang, Watanabe, Wilson, Wisniewski, Wisniewski, Withers, Wood, Wyss-Coray, Yang, Ye, Yeh, Yuan, Zerbinatti, Zhang, Zhang, Zlokovic   +207 more
core   +2 more sources

Phorbol esters affect multiple steps in beta-amyloid precursor protein trafficking and amyloid beta-protein production.

Molecular medicine (Cambridge, Mass.), 1997
Amyloid beta-protein (A beta), the major constituent of amyloid deposits found in Alzheimer's disease, is derived from the beta-amyloid precursor protein (beta PP). Constitutive proteolysis by alpha-secretase and secretion of soluble beta PP (beta PPs) are stimulated by protein kinase C (PKC) activation, whereas A beta production and release are ...
openaire   +1 more source

Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa.

Journal of Clinical Investigation, 1993
Alvin H. Schmaier, Linda D. Dahl, Annemieke, J., M. Rozemuller, Raymund, A. C. Roos, Steven, L. Wagner, Raymond, Chung, E. William, '. VanNostrand   +12 more
semanticscholar   +1 more source

Amyloid Alpha: The Neglected Cousin of Amyloid Beta. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

Protease nexin-2/amyloid beta-protein precursor: a cerebral anticoagulant? [PDF]

Journal of Clinical Investigation, 1993
openaire   +1 more source

Potential correlation between chronic pain and amyloid beta in Alzheimer's disease. [PDF]

Front Pain Res (Lausanne)
Liu Y, Wang XP.
europepmc   +1 more source

The mRNA Expression Levels of General Transcription Factors Altered in Alzheimer Cases Possibly Due to Amyloid Beta 1-42 Exposure. [PDF]

Noro Psikiyatr Ars
İlhan N, Keskin E, Şahin E, Alaylıoğlu M, Samancı B, Çamoğlu T, Yurttaş Z, Sordu P, Ildız S, Ayaz G, Yediel BŞ, Azzouz SS, Bilgiç B, Hanağası HA, Gürvit İH, Ak DG, Dursun E.   +16 more
europepmc   +1 more source