Results 181 to 190 of about 94,035 (378)
Activation of mTOR: a culprit of Alzheimer’s disease?
Neuropsychiatric Disease and Treatment, 2015 Zhiyou Cai,1 Guanghui Chen,1 Wenbo He,1 Ming Xiao,2 Liang-Jun Yan31Department of Neurology, Renmin Hospital, Hubei University of Medicine, Shiyan Renmin Hospital, Shiyan, Hubei Province, People’s Republic of China; 2Department of Anatomy, Nanjing ...
Cai Z, Chen G, He W, Xiao M, Yan LJ
doaj
Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6 [PDF]
, 2016 Kaichuan Zhu +12 more
openalex +1 more source
The fate of interneurons, GABAA receptor sub‐types and perineuronal nets in Alzheimer's disease
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Abstract Alzheimer's disease (AD) is the most common neurological disease, which is associated with gradual memory loss and correlated with synaptic hyperactivity and abnormal oscillatory rhythmic brain activity that precedes phenotypic alterations and is partly responsible for the spread of the disease pathology.
Afia B. Ali +2 more
wiley +1 more source
Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism [PDF]
, 2016 Cara J. Westmark +3 more
openalex +1 more source
Glia, EarlyView.Amyloid‐β peptide induces early oligodendrocyte differentiation and dorsal myelination in the zebrafish larvae spinal cord. Pan‐PKC inhibitor Gö6983 restores the aforementioned alterations in oligodendrocytes and myelin. ABSTRACT Soluble forms of amyloid‐β (Aβ) peptide have been proposed as candidates to induce oligodendrocyte (OL) and myelin ...
Uxue Balantzategi +7 more
wiley +1 more source
Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism [PDF]
, 2018 Fawaz Alasmari +4 more
openalex +1 more source
Research progress of neurovascular units involved in ischemic stroke
Ibrain, EarlyView.The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang +4 more
wiley +1 more source
Neurobiology of Disease, 2011 There is strong evidence that intracellular calcium dysregulation plays an important pathological role in Alzheimer's disease, and specifically that beta amyloid may induce increases in intracellular calcium and lead to neuronal cell dysfunction and ...
Thimmappa S. Anekonda +5 more
doaj