Results 141 to 150 of about 20,912 (233)

Therapeutic and preventive strategies based on the maladaptive plasticity hypothesis for Alzheimer's disease. [PDF]

Front Aging Neurosci
Kawabata S.
europepmc   +1 more source

Investigations of γ-secretase substrates Amyloid precursor protein and p75 neurotrophin receptor in zebrafish

, 2019
Tanya Jayne
openalex   +1 more source

Liraglutide attenuates aluminum chloride-induced Alzheimer's disease in rats by modulating the oxLDL/LPA/LPAR1 pathway. [PDF]

Commun Biol
Abo El-Magd NF, Ramadan NM, Eraky SM.
europepmc   +1 more source

Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2

, 2015
Xiaoguang Yang, Sheng Wang, Devin M. Ridgley, Mark A. Haidekker, Grace Y. Sun, J.C. Lee   +5 more
openalex   +1 more source

Amyloid β-Protein Precursor Juxtamembrane Domain Regulates Specificity of γ-Secretase-dependent Cleavages [PDF]

, 2007
Zhao Ren, Dale Schenk, Guriqbal S. Basi, Igor Shapiro   +3 more
openalex   +1 more source

Evidence that extra copies of chromosome 1q play a role in the early phases of pancreatic neoplasia. [PDF]

Sci Adv
Douville C, Parksong J, Dal Molin M, Graham S, Greipp PT, Knudson R, Curtis S, Wang Y, Dobbyn L, Popoli M, Ptak J, Silliman N, Romans K, Iacobuzio-Donahue CA, Makoohon-Moore AP, Lennon AM, Goggins M, Hruban RH, Kiemen A, Bettegowda C, Kinzler KW, Papadopoulos N, Wood LD, Vogelstein B.   +23 more
europepmc   +1 more source

APP family is a regulator of endo-lysosomal membrane vulnerability. [PDF]

J Biol Chem
Lundin B, Wieckiewicz N, Yokomizo M, Sadek M, Kwarteng DO, Dickson JR, Sobolewski RGR, Derosla V, Armagan G, Perrin F, Hyman BT, Berezovska O, Maesako M.   +12 more
europepmc   +1 more source

Retinoic Acid-Elicited RARα/RXRα Signaling Attenuates Aβ Production by Directly Inhibiting γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein

, 2013
Arun Kapoor, Bo‐Jeng Wang, Wen‐Ming Hsu, Ming‐Yun Chang, Shu‐Mei Liang, Yung-Feng Liao   +5 more
openalex   +1 more source

Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse. [PDF]

Fluids Barriers CNS
Embalabala RJ, Masters H, Ziehm E, Pouncey J, Kim H, Lippmann ES.   +5 more
europepmc   +1 more source

The molecular link between β- and γ-secretase activity on the amyloid β precursor protein

, 2007
Massimo Tabaton, Elena Tamagno
openalex   +2 more sources