Results 101 to 110 of about 18,838 (278)

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Single-cell Motility Analysis of Tethered Human Spermatozoa. [PDF]

, 2019
Vigorous sperm flagellar motility is essential for fertilization, and so the quantitative measurement of motility is a useful tool to assess the intrinsic fertility potential of sperm cells and explore how various factors can alter sperm's ability to ...
Lishko, Polina V, Mannowetz, Nadja, Roan, Nadia R, Skinner, William M   +3 more
core  

Molecular Dynamics Studies on 3D Structures of the Hydrophobic Region PrP(109-136) [PDF]

, 2013
Prion diseases caused by the conversion from a soluble normal cellular prion protein into insoluble abnormally folded infectious prions, are invariably fatal and highly infectious degenerative diseases that affect a wide variety of mammalian species. The
Zhang, Jiapu, Zhang, Yuanli
core   +4 more sources

Amyloid goitre [PDF]

Journal of Clinical Pathology, 1972
Amyloid goitre is a rare manifestation of amyloidosis; about 50 cases have been recorded and this paper adds a further six cases, the first to be described from Uganda. The condition has to be distinguished from the more common types of goitre, and histological differentiation from medullary carcinoma may be difficult with small biopsies.
openaire   +2 more sources

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Innovative solutions to sticky situations: Antiadhesive strategies for treating bacterial infections [PDF]

, 2016
Bacterial adherence to host tissue is an essential process in pathogenesis, necessary for invasion and colonization and often required for the efficient delivery of toxins and other bacterial effectors.
Aberg, Abgottspon, Allen, Allison, Alves, Aminov, Anderson, Andersson, Andersson, Andreini, Anthouard, Arnqvist, Aronson, Arrecubieta, Ashkar, Autar, Avorn, Bajolet-Laudinat, Barbosa-Cesnik, Barczak, Barnhart, Barnhart, Barocchi, Blanco, Bouckaert, Bouckaert, Boukerb, Boyle, Branderhorst, Breimer, Breimer, Briles, Britton, Brown, Buffie, Candela, Cecioni, Cecioni, Cegelski, Chabre, Chagnot, Chang, Chapman, Chemani, Chen, Chen, Chorell, Choudhury, Cioci, Clatworthy, Cole, Coppa, Cossart, Costerton, Cozens, Cusumano, Dam, Delnay, DePas, Dethlefsen, Diggle, Dodson, Donlan, Dramsi, Ebersbach, Eto, Evans, Fagon, Falugi, Ferreira, Findlow, Finlay, Finlay, Fischetti, Flores-Mireles, Foo, Ford, Foxman, Frankel, Furiga, Gao, Garcia-Medina, Gaudreau, Geibel, Gellatly, Ghosh, Giugliano, Glick, Goller, Gouin, Goyal, Greco, Greene, Griebling, Guiton, Guiton, Guiton, Guiton, Gustafsson, Guttilla, Haataja, Hakkarainen, Hammar, Hammer, Hammer, Hampton, Han, Han, Hansson, Hart, Haslam, Hauck, Hawley, Hentzer, Hernell, Hofmann, Hollenbeck, Horvath, Howell, Hung, Hung, Hur, Hur, Idanpaan-Heikkila, Isberg, Jacob-Dubuisson, Jay, Jiang, Jones, Jones, Joosten, Juliano, Kadam, Kadam, Kai-Larsen, Kang, Kang, Kauppi, Keeney, Kelly, Kierek-Pearson, Kim, Kim, Kim, Kisiela, Kleeb, Klein, Klein, Klein, Kline, Kontiokari, Konto-Ghiorghi, Korhonen, Kozel, Krachler, Krachler, Krachler, Kruger, Kummerfeldt, Langermann, Langermann, Lanne, Lanne, Larsson, Lebeaux, Lee, Lee, Lee, Lehner, Lewis, Li, Liu, Liukkonen, Lo, Loveless, Lund, Lyczak, Ma, Mack, Mamo, Mandlik, Manefield, Mapingire, Maresso, Maresso, Maresso, Marotte, Marraffini, Mayville, Mazmanian, Mazmanian, Menard, Migone, Migone, Miller, Mitchell, Morrow, Morvan, Munera, Murray, Mysore, Nallapareddy, Neeser, Nenninger, Nenninger, Newburg, Nicolle, Nielsen, Nielsen, Nielubowicz, Nishikawa, Nishikawa, Nishiyama, Nuccio, O'Toole, Ofek, Ofek, Oh, Oh, Oh, Ohlsson, Ohlsson, Okuda, Olsen, Oppong, Orndorff, Otsuka, Paganelli, Pak, Palumbi, Pang, Park, Parker, Patel, Perret, Pertici, Peychl, Phan, Piatek, Pieters, Pinkner, Prabu, Proft, Puorger, Pusztai, Raghunathan, Rapsinski, Rasko, Remaut, Remaut, Rivera, Roberts, Robinson, Rosen, Ruiz-Palacios, Saeki, Saldana, Salminen, Sauer, Sauer, Savar, Scharenberg, Schlager, Schneewind, Schroten, Schulte, Schwardt, Scott, Sekirov, Serruto, Sheth, Shu, Signoretto, Smith, Song, Staat, Stamm, Starkey, Steadman, Stromqvist, Su, Svensson, Thanassi, Therrien, Thomas, Tielker, Toivanen, Ton-That, Ton-That, Ton-That, Ton-That, Turgeon, Ubeda, Van Houdt, Vangay, Vengadesan, Volkan, Walsh, Wang, Wang, Wellens, Whittaker, Wilson, Wolinsky, Wu, Wu, Wurpel, Xiao, Yamaguti-Sasaki, Yamanaka, Yanagawa, Younson, Zhang, Zhang, Zinger-Yosovich   +314 more
core   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Periodontitis, microbiomes and their role in Alzheimer’s disease [PDF]

, 2017
As far back as the eighteenth and early nineteenth centuries, microbial infections were responsible for vast numbers of deaths. The trend reversed with the introduction of antibiotics coinciding with longer life.
Crean, Stjohn, Olsen, Ingar, Pritchard, Anna, Singhrao, Simarjit Kaur   +3 more
core   +2 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source