Results 81 to 90 of about 18,947 (293)
Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma +9 more
wiley +1 more source
Cells, 2020 Protein aggregation is associated with an increasing number of human disorders and premature aging. Moreover, it is a central concern in the manufacturing of recombinant proteins for biotechnological and therapeutic applications. Nevertheless, the unique
Jaime Santos +6 more
doaj +1 more source
, 1982 Monthly newsletter providing updates of interest to the Boston University School of Medicine community.In Print, a listing of Boston University School of Medicine faculty ...
Boston University School of Medicine Office of Informational Services
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Stimulated Emission from Rhodamine 6G Aggregates Self-Assembled on Amyloid Protein Fibrils [PDF]
, 2015 Amyloid fibrils are excellent bioderived nanotemplates for controlling molecular and optical properties of small molecules such as organic dyes. Here we demonstrate that two representative fibril-forming proteins, lysozyme and insulin, from the amyloids ...
Hanczyc, Piotr +3 more
core +2 more sources
Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt +8 more
wiley +1 more source
Failure of Aβ(1-40) amyloid fibrils under tensile loading [PDF]
, 2010 Amyloid fibrils and plaques are detected in the brain tissue of patients affected by Alzheimer’s disease, but have also been found as part of normal physiological processes such as bacterial adhesion.
Buehler, Markus J, Paparcone, Raffaella
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Biofilm-associated proteins: from the gut biofilms to neurodegeneration
Gut MicrobesHuman microbiota form a biofilm with substantial consequences for health and disease. Numerous studies have indicated that microbial communities produce functional amyloids as part of their biofilm extracellular scaffolds.
Jaione Valle
doaj +1 more source
Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers [PDF]
, 2019 Desmin-associated myofibrillar myopathy (MFM) has pathologic similarities to neurodegeneration-associated protein aggregate diseases. Desmin is an abundant muscle-specific intermediate filament, and disease mutations lead to its aggregation in cells ...
Arhzaouy, Khalid +6 more
core +1 more source
The propensity of the bacterial rodlin protein RdlB to form amyloid fibrils determines its function in Streptomyces coelicolor. [PDF]
, 2017 Streptomyces bacteria form reproductive aerial hyphae that are covered with a pattern of pairwise aligned fibrils called rodlets. The presence of the rodlet layer requires two homologous rodlin proteins, RdlA and RdlB, and the functional amyloid chaplin ...
Claessen, Dennis +8 more
core +3 more sources