Results 31 to 40 of about 11,917 (183)

Membrane transport of anandamide through resealed human red blood cell membranes

open access: yesJournal of Lipid Research, 2005
The use of resealed red blood cell membranes (ghosts) allows the study of the transport of a compound in a nonmetabolizing system with a biological membrane.
Inge N. Bojesen, Harald S. Hansen
doaj   +1 more source

Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida   +10 more
wiley   +1 more source

Differentiating Nonsuicidal Self‐Injury (NSSI) From Suicide Attempts in Adolescents: A Pilot Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Differentiating between nonsuicidal self‐injury (NSSI) and suicide attempts (SA) in adolescents is crucial due to distinct underlying motivations, treatment needs, and potential outcomes associated with each behavior.
María Posada‐Ayala   +9 more
wiley   +1 more source

Cannabinoid Receptor Activation Disrupts the Internal Structure of Hippocampal Sharp Wave–Ripple Complexes

open access: yesJournal of Pharmacological Sciences, 2012
Cannabinoid agonists impair hippocampus-dependent learning and memory. Using mouse hippocampal slice preparations, we examined the effect of anandamide, an endogenous cannabinoid, on sharp wave–ripple (SW-R) complexes, which are believed to mediate ...
Yi Sun   +4 more
doaj   +1 more source

Endocannabinoid anandamide mediates hypoxic pulmonary vasoconstriction [PDF]

open access: yesProceedings of the National Academy of Sciences, 2013
SignificanceHypoxic pulmonary vasoconstriction (HPV) is an important physiological reflex, which is only found in the lung and adapts perfusion to ventilation. HPV is potentially involved in hypoxia-induced pulmonary hypertension (PH) occurring in respiratory disorders.
Daniela, Wenzel   +6 more
openaire   +2 more sources

Research Progress on Upper Airway Cough Syndrome

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Anandamide mitigates ischemia/reperfusion (I/R)-induced gastric ulcer: modulation of inflammation and oxidative stress

open access: yesZagazig Journal of Pharmaceutical Sciences, 2015
Anandamide is a cannabinoid receptors agonist that showed a protective effect against intestinal I/R model. However, its modulatory effect on I/R-induced gastric ulcer has not been previously elucidated.
Shahata H , El-Abhar H , El-Maraghy N
doaj   +1 more source

Endocannabinoid system gene expression in mesocorticolimbic brain regions of individuals with alcohol use disorder: A descriptive study

open access: yesAddiction, EarlyView.
Abstract Aims To describe differences in the expression of genes encoding cannabinoid receptors (CNR1, CNR2), the associated receptor GRP55 and the enzymes fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MGLL) between individuals with alcohol use disorder (AUD) and controls in key mesocorticolimbic brain regions.
María Salud García‐Gutiérrez   +5 more
wiley   +1 more source

Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review

open access: yesFrontiers in Endocrinology, 2021
The endocannabinoid system (ECS) is a cell-signaling system present in multiple organ systems and is an integral part of sustaining the microenvironment necessary for early pregnancy success and maintenance.
Melissa L. Kozakiewicz   +2 more
doaj   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

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