Results 71 to 80 of about 11,917 (183)

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 1, February 2026.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter, Simon Erridge, John Warner‐Levy, Evonne Clarke, Katy McLachlan, Ross Coomber, Shelley Barnes, Alia Darweish Medniuk, Rahul Guru, Wendy Holden, Mohammed Sajad, Robert Searle, Azfer Usmani, Sanjay Varma, James J. Rucker, Michael Platt, Mikael H. Sodergren   +16 more
wiley   +1 more source

Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats

International Journal of Hypertension, 2012
In rat isolated mesenteric beds that were contracted with NA as an in vitro model of the vascular adrenergic hyperactivity that usually precedes the onset of primary hypertension, the oral administration (3 daily doses) of either 10 mg/kg genistein or 20 
Roxana N. Peroni, Tamara Abramoff, Isabel Neuman, Ernesto J. Podestá, Edda Adler-Graschinsky   +4 more
doaj   +1 more source

Oxyradical Stress, Endocannabinoids, and Atherosclerosis

Toxics, 2015
Atherosclerosis is responsible for most cardiovascular disease (CVD) and is caused by several factors including hypertension, hypercholesterolemia, and chronic inflammation.
Anberitha T. Matthews, Matthew K. Ross
doaj   +1 more source

Palmitoylethanolamide (PEA) regulates cell cycle progression and promotes an anti‐inflammatory transcriptomic signature in C2C12 skeletal muscle cells

Physiological Reports, Volume 14, Issue 4, February 2026.
Abstract Palmitoylethanolamide (PEA) is an endogenous lipid mediator with immunomodulatory actions, yet its effects in skeletal muscle remain poorly defined. We examined whether PEA influences myogenesis and profiled the acute transcriptomic response of differentiated C2C12 myotubes to 10 μM PEA. PEA decreased myotube number (90.3 ± 10.6 vs. 112.6 ± 10.
Paige L. Cole, Scott H. Gillham, Mark R. Viggars, Graeme L. Close, Daniel J. Owens   +4 more
wiley   +1 more source

Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat[S]

Journal of Lipid Research, 2016
Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their ...
Miriam Jacome-Sosa, Claudia Vacca, Rabban Mangat, Abdoulaye Diane, Randy C. Nelson, Martin J. Reaney, Jianheng Shen, Jonathan M. Curtis, Donna F. Vine, Catherine J. Field, Miki Igarashi, Daniele Piomelli, Sebastiano Banni, Spencer D. Proctor   +13 more
doaj   +1 more source

Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma

Journal of Lipid Research, 2010
The endocannabinoid metabolome consists of a growing, (patho)physiologically important family of fatty-acid derived signaling lipids. Diet is a major source of fatty acid substrate for mammalian endocannabinoid biosynthesis. The principal long-chain PUFA
JodiAnne T. Wood, John S. Williams, Lakshmipathi Pandarinathan, David R. Janero, Carol J. Lammi-Keefe, Alexandros Makriyannis   +5 more
doaj   +1 more source

Endocannabinoid Systetm: Neuropharmacological Implications

Medicine Science, 2016
Marijuana or cannabis has been part of humanity's medicine chest for almost as long as history has been recorded. Cannabinoids are a class of diverse chemical compounds isolated from cannabis that act on cannabinoid receptors (CB1 & CB2).
Vivek Kumar Sharma, Akshay Chandel, Gunad Acharya, Rahul Deshmukh   +3 more
doaj   +1 more source

An Analysis of Endocannabinoid Concentrations and Mood Following Singing and Exercise in Healthy Volunteers

Frontiers in Behavioral Neuroscience, 2018
The euphoric feeling described after running is, at least in part, due to increased circulating endocannabinoids (eCBs). eCBs are lipid signaling molecules involved in reward, appetite, mood, memory and neuroprotection.
Nicole L. Stone, Sophie A. Millar, Philip J. J. Herrod, David A. Barrett, Catharine A. Ortori, Valerie A. Mellon, Saoirse E. O’Sullivan   +6 more
doaj   +1 more source

EFFECT OF CANNABINOIDS ON TESTICULAR ISCHEMIA-REPERFUSION INJURY IN RAT

Acta Medica Iranica, 2006
Anandamide is an endogenous ligand for cannabinoid receptors and has endothelial protective effect against ischemic preconditioning. The purpose of this study was to investigate the effects of cannabinoids on reperfusion injury due to testicular torsion ...
R. Rabani, H. R. Sadeghipour-Roodsari, H. Sepehri, A. A. Hassanzadeh-Salmasi A. R. Dehpour   +3 more
doaj  

Biotin-anandamide: a new tool to visualize anandamide inside the cells

, 2010
L’endocannabinoide anandamide è un lipide neuromodulatorio non carico che è inattivato grazie al suo assorbimento cellulare e successivo catabolismo. Mentre la biosintesi e la degradazione dell’anandamide sono state chiarite in dettaglio, il meccanismo attraverso cui essa entra all’interno della cellula rimane ancora non chiaro.
openaire   +2 more sources