Results 11 to 20 of about 26,112 (181)

Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD) [PDF]

International Journal of Endocrinology, 2021
Background. Metabolic surgery procedures are designed not only for sustained weight loss but also for achieving positive metabolic changes, including improved glucose tolerance and insulin sensitivity, along with an increase in energy expenditure.
Tomasz Sawczyn, Dominika Stygar, Katarzyna Nabrdalik, Michał Kukla, Oliwia Masri, Łukasz Magrowski, Wojciech Karcz, Jerzy Jochem   +7 more
doaj   +2 more sources

Angiopoietin-like protein 8 orchestrates macrophage glycogen metabolism and polarization via the JNK signaling pathway in cytokine storm syndrome [PDF]

Cell & Bioscience
Cytokine storm syndrome (CSS) is associated with severe damage and high mortality in acute diseases. Over-activation of M1 macrophages, accompanied with excessive pro-inflammatory cytokine secretion, drives cytokine storms, while promoting M2 macrophage ...
Yang Su, Rongtian Zhang, Kongdong Li, Hong Shen, Mengjiao Nan, Chang Liu, Wenxiang Zhang, Siyu Chen   +7 more
doaj   +2 more sources

Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity

Heliyon, 2021
We previously demonstrated that angiopoietin-like protein 8 (ANGPTL8) forms ANGPTL3/8 and ANGPTL4/8 complexes that increase with feeding to direct fatty acids (FA) toward adipose tissue through differential modulation of lipoprotein lipase (LPL) activity.
Yan Q. Chen, Thomas G. Pottanat, Robert W. Siegel, Mariam Ehsani, Yue-Wei Qian, Robert J. Konrad   +5 more
doaj   +3 more sources

Circulating angiopoietin-like protein 8 (ANGPTL8) and steatotic liver disease related to metabolic dysfunction: an updated systematic review and meta-analysis [PDF]

Frontiers in Endocrinology
BackgroundSteatotic liver disease related to metabolic dysfunction is the most common cause of chronic liver disease globally. The spectrum of this condition includes steatosis and steatohepatitis and was previously referred to as non-alcoholic fatty ...
Farah Abdelhameed, Farah Abdelhameed, Lukasz Lagojda, Lukasz Lagojda, Chris Kite, Chris Kite, Chris Kite, Alexander Dallaway, Alexander Dallaway, Attia Mustafa, Attia Mustafa, Attia Mustafa, Attia Mustafa, Attia Mustafa, Nwe Ni Than, Eva Kassi, Eva Kassi, Harpal S. Randeva, Harpal S. Randeva, Harpal S. Randeva, Harpal S. Randeva, Ioannis Kyrou, Ioannis Kyrou, Ioannis Kyrou, Ioannis Kyrou, Ioannis Kyrou, Ioannis Kyrou, Ioannis Kyrou   +27 more
doaj   +2 more sources

Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases [PDF]

Jichu yixue yu linchuang
Angiopoietin-like protein 8(ANGPTL8) secreted by liver and adipose tissue, is a glycoprotein exerting paramount effects on facilitation of vascular remodeling and regulation of inflammatory response; ANGPTL8 is involved in the initiation and progression ...
HAN Lijie, HU Chaowei, YU Huahui, QIN Yanwen
doaj   +2 more sources

Association of Serum Angiopoietin-Like Protein 8 With Albuminuria in Type 2 Diabetic Patients: Results From the GDMD Study in China [PDF]

Frontiers in Endocrinology, 2018
Background: Hyperglycemia, insulin resistance and hypertriglyceridesmia are risk factors for albuminuria in type 2 diabetes. Angiopoietin-like Protein 8(ANGPTL8) is a newly identified liver-derived hormone related to these risk factors.
Liuxue Yang, Jianfei Song, Xiaoxi Zhang, Liuping Xiao, Xueping Hu, Haidong Pan, Linyuan Qin, Hongbo Liu, Bo Ge, Tianpeng Zheng, Tianpeng Zheng   +10 more
doaj   +2 more sources

Triglyceride-mediated influence of serum angiopoietin-like protein 8 on subclinical atherosclerosis in type 2 diabetic patients: results from the GDMD study in China [PDF]

Cardiovascular Diabetology, 2018
Background Hypertriglyceridemia, insulin resistance and hyperglycemia are risk factors for atherosclerosis in type 2 diabetes. Angiopoietin-like protein 8 (ANGPTL8) is a newly identified liver-derived hormone related to these risk factors.
Tianpeng Zheng, Bo Ge, Hongbo Liu, Bo Chen, Linyuan Qin, Liuping Xiao, Jianfei Song   +6 more
doaj   +2 more sources

Apolipoprotein CIII and Angiopoietin-like Protein 8 are Elevated in Lipodystrophy and Decrease after Metreleptin. [PDF]

J Endocr Soc, 2021
Abstract Context Lipodystrophy syndromes cause hypertriglyceridemia that improves with leptin treatment using metreleptin. Mechanisms causing hypertriglyceridemia and improvements after metreleptin are incompletely understood. Objective
Lightbourne M, Wolska A, Abel BS, Rother KI, Walter M, Kushchayeva Y, Auh S, Shamburek RD, Remaley AT, Muniyappa R, Brown RJ.   +10 more
europepmc   +4 more sources

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS [PDF]

BMC Medicine
Background Alterations in lipid metabolism are manifestations of amyotrophic lateral sclerosis (ALS) that contribute to the risk and rate of progression.
Sruthi Sankari Krishnamurthy, Adriana Zardini Buzatto, Caley Campkin, Hans-Peter Müller, Diana Wiesner, Jochen Weishaupt, Veronika Klose, Maximilian Wiesenfarth, Zeynep Elmas, Christine Herrmann, Özlem Parlak, Kornelia Günther, Rami Saad, Ulrike Weiland, Luc Dupuis, Albert Ludolph, Liang Li, Jan Kassubek, Johannes Dorst, Francesco Roselli   +19 more
doaj   +2 more sources

Angiopoietin-like protein 8 promotes phenotypic transformation of rat aorta vascular smooth muscle cells [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore the role and mechanism of angiopoietin-like protein 8 (ANGPTL8) on phenotypic transformation of rat aorta vascular smooth muscle cells (VSMCs).
SUN Qiu-ju, JIAO Xiao-lu, YU Hua-hui, LI Fan, LYU Qian-wen, WANG Yu, QIN Yan-wen
doaj   +1 more source