Results 31 to 40 of about 96,838 (221)

Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease. [PDF]

Cardiovasc Diabetol, 2018
BackgroundThe aim of the present study was to examine the association of angiopoietin-like proteins-8 (ANGPTL8) rs2278426, cholesteryl ester-transfer protein (CETP) rs708272 and endothelial nitric oxide synthase (NOS3) rs1799983 variants with type 2 ...
El-Lebedy D.
europepmc   +2 more sources

THE RELATIONSHIP BETWEEN SERUM ANGIOPOIETIN-LIKE PROTEIN 8 LEVELS AND HYPERTENSION STAGES

Kocatepe Tıp Dergisi
OBJECTIVE: Hypertension is a serious condition that can lead to serious complications. Currently, there is no standard biomarker used in clinical practice to diagnose hypertension and stage the disease.
Güney Sarıoğlu, İbrahim Aktaş
semanticscholar   +3 more sources

Angiopoietin-like protein 8 promotes apoptosis of vascular smooth muscle cells through activating p53 signaling pathway [PDF]

Jichu yixue yu linchuang
Objective To investigate the mechanism by which angiopoietin-like protein 8 (ANGPTL8) regulates vascular smooth muscle cell (VSMCs) apoptosis. Methods An in vitro abdominal aortic aneurysm cell model was established by stimulating human VSMCs(HUSMCs ...
YU Huahui, DU Zhiyong, JIAO Xiaolu, LYU Qianwen, YANG Yunyun, HAN Lijie, QIN Yanwen
doaj   +2 more sources

Research progress on the roles of angiopoietin-like protein 8 in the pathogenesis of cardiovascular diseases [PDF]

Jichu yixue yu linchuang
Angiopoietin-like protein 8(ANGPTL8) secreted by liver and adipose tissue, is a glycoprotein exerting paramount effects on facilitation of vascular remodeling and regulation of inflammatory response; ANGPTL8 is involved in the initiation and progression ...
HAN Lijie, HU Chaowei, YU Huahui, QIN Yanwen
doaj   +2 more sources

Apolipoprotein CIII and Angiopoietin-like Protein 8 are Elevated in Lipodystrophy and Decrease after Metreleptin. [PDF]

J Endocr Soc, 2021
Abstract Context Lipodystrophy syndromes cause hypertriglyceridemia that improves with leptin treatment using metreleptin. Mechanisms causing hypertriglyceridemia and improvements after metreleptin are incompletely understood. Objective
Lightbourne M, Wolska A, Abel BS, Rother KI, Walter M, Kushchayeva Y, Auh S, Shamburek RD, Remaley AT, Muniyappa R, Brown RJ.   +10 more
europepmc   +4 more sources

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS [PDF]

BMC Medicine
Background Alterations in lipid metabolism are manifestations of amyotrophic lateral sclerosis (ALS) that contribute to the risk and rate of progression.
Sruthi Sankari Krishnamurthy, Adriana Zardini Buzatto, Caley Campkin, Hans-Peter Müller, Diana Wiesner, Jochen Weishaupt, Veronika Klose, Maximilian Wiesenfarth, Zeynep Elmas, Christine Herrmann, Özlem Parlak, Kornelia Günther, Rami Saad, Ulrike Weiland, Luc Dupuis, Albert Ludolph, Liang Li, Jan Kassubek, Johannes Dorst, Francesco Roselli   +19 more
doaj   +2 more sources

Relationship Between Angiopoietin-Like Protein 8 and Fasting Serum Triglyceride Level. [PDF]

J Clin Med Res, 2018
The aim of the study was to evaluate the correlation between angiopoietin-like protein 8 (ANGPTL8) and metabolic parameters in non-diabetic healthy humans.We enrolled 30 healthy Japanese adults (25 men and five women). After 9 h of fasting, we collected blood samples and analyzed the ANGPTL8, lipoprotein lipase (LPL), plasma lipid and glucose metabolic
Yamada H, Kusaka I, Saikawa R, Hara K, Kakei M, Ishikawa SE.   +5 more
europepmc   +4 more sources

Corrigendum to "Angiopoietin-Like Protein 8 Expression and Association With Extracellular Matrix Metabolism and Inflammation During Intervertebral Disc Degeneration". [PDF]

J Cell Mol Med
europepmc   +2 more sources

The potential role of angiopoietin-like protein-8 in type 2 diabetes mellitus: a possibility for predictive diagnosis and targeted preventive measures? [PDF]

EPMA J, 2019
Issa YA, Abd ElHafeez SS, Amin NG.
europepmc   +2 more sources

Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome. [PDF]

Cardiovasc Diabetol, 2016
ANGPTL8 also called betatrophin is a regulator of lipid metabolism through its interaction with ANGPTL3. It has also been suggested to play a role in insulin resistance and beta-cell proliferation. Based on its function, we hypothesized that ANGPTL8 will play a role in Metabolic Syndrome (MetS). To test this hypothesis we designed this study to measure
Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Kavalakatt S, Khadir A, Behbehani K, Alarouj M, Bennakhi A, Elkum N.   +10 more
europepmc   +4 more sources