Results 41 to 50 of about 96,838 (221)
Angiopoietin-like protein 8 in early pregnancy improves the prediction of gestational diabetes [PDF]
Diabetologia, 2018 Screening high-risk individuals for gestational diabetes mellitus (GDM) in early pregnancy conventionally relies on established maternal risk factors; however, the sensitivity and specificity of these factors are not satisfactory. The present study aimed to determine whether the concentration of angiopoietin-like protein 8 (ANGPTL8), either alone or ...
Yun Huang +10 more
semanticscholar +3 more sources
Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
, 2013 We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Chillo, Omary +6 more
core +15 more sources
Host Factors Alter Effects of Angiopoietin-Like Protein 8 on Glucose Homeostasis in Diabetic Mice. [PDF]
J Diabetes Mellitus, 2016 Recovery of functional beta cell mass offers a biological cure for type 1 diabetes. However, beta cell mass is difficult to regain once lost since the proliferation rate of beta cells after youth is very low. Angiopoietin like-protein 8 (ANGPTL8), a peptide that has a role in the regulation of lipoprotein lipase activity, was reported to increase beta ...
Liu S +11 more
europepmc +4 more sources
A Short Review on ANGPTL-8 as an Important Regulator in Diabetes [PDF]
Avicenna Journal of Medical Biochemistry, 2019 ANGPTL8, a new hormone, is regarded as a novel target for type-2 diabetes and associated metabolic disorder. Nutritional state and hormonal factors are involved in the regulation of ANGPTL-8 expression.
Maryam Esfahani, Mohammad Taghi Goodarzi
doaj +1 more source
Frontiers in Endocrinology, 2023 Angiopoietin-like proteins (ANGPTLs) mediate many metabolic functions. We had recently reported increased plasma levels of ANGPTL8 in obese adults of Arab ethnicity. However, data on ANGPTL8 levels in adolescent obesity is lacking.
Maha M. Hammad +10 more
doaj +1 more source
Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2015 Circulating ANGPTL8 has recently been used as a marker of insulin action. We studied expression and insulin regulation of ANGPTL8 and ANGPTL3 in vivo and in vitro.Expression of ANGPTL8 and ANGPTL3 was studied in 34 paired samples of human liver and adipose tissue.
Haridas, P. A. Nidhina +16 more
openaire +3 more sources
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2022 Thoracic aortic aneurysm/dissection (TAAD) is a life-threatening cardiovascular disorder. Endoplasmic reticulum stress (ERS) and vascular smooth muscle cell (VSMC) apoptosis are involved in TAAD progression.
Yunxiao Yang +6 more
semanticscholar +1 more source
Animal Biotechnology, 2021 This study aimed to clone the full-length open reading frame (ORF) of goat ANGPTL8 gene sequence, reveal its molecular and expression characteristics, and explore its effect on the differentiation of goat intramuscular preadipocytes. The full-length ORF sequence of goat ANGPTL8 gene was cloned by RT-PCR technology, and bioinformatics analysis was ...
Wei Huang +4 more
openaire +2 more sources
Hepatology, EarlyView., 2022 Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince +30 more
wiley +1 more source
Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea [PDF]
Frontiers in Endocrinology, 2018 Objective: Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health complications, such as hypertension, cardiovascular disease, and Type 2 diabetes. Angiopoietin-like protein (
Abdulmohsen Al-Terki +9 more
openaire +3 more sources