Results 161 to 170 of about 107,653,743 (272)

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

open access: yesAdvanced Science, Volume 13, Issue 59, 23 October 2026.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang   +14 more
wiley   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu   +8 more
wiley   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh   +2 more
wiley   +1 more source

Decreased circulating levels of angiopoietin - 1 (Ang-1) are associated with the presence of multinodular goiter or differentiated thyroid cancer. [PDF]

open access: yesSurg Pract Sci, 2023
Nixon AM   +8 more
europepmc   +1 more source

Dodonaea viscosa in Breast Cancer: Phytochemistry, Anticancer Mechanisms, and Emerging Immunotherapeutic and Translational Perspectives

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Breast cancer remains a leading cause of cancer‐related mortality among women worldwide, with treatment resistance, disease heterogeneity, and therapy‐associated toxicities limiting clinical outcomes. Its major clinically relevant subtypes, including oestrogen receptor‐positive (ER+), human epidermal growth factor receptor 2‐positive (HER2 ...
Nireshini Reddy   +5 more
wiley   +1 more source

Dual gene-activated dermal scaffolds regulate angiogenesis and wound healing by mediating the coexpression of VEGF and angiopoietin-1. [PDF]

open access: yesBioeng Transl Med, 2023
Weng T   +10 more
europepmc   +1 more source

Fisetin Attenuates Human Macrophage Polarization and Pro‐Inflammatory Responses via NLRP3 and NF‐κB/MAPK Suppression

open access: yesCell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Natural compounds with anti‐inflammatory properties are increasingly explored as therapeutic agents due to their lower risk of side effects compared with conventional drugs. Fisetin, a dietary bioflavonol abundant in fruits and vegetables, exhibits anti‐inflammatory activity in several cell types, including murine macrophages.
Nattaya Onpan   +7 more
wiley   +1 more source

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