Results 171 to 180 of about 107,653,743 (272)

Serum Angiopoietin-1 and Angiopoietin-2 as Biomarkers of Pulmonary Hemodynamic Burden in COPD-Associated Pulmonary Hypertension: A Cross-Sectional Study. [PDF]

Adv Respir Med
Bajpai J, Pradhan A, Ahmad MK, Kant S, Verma AK, Bajaj DK, Sethi R, Cazzola M.   +7 more
europepmc   +1 more source

Early therapeutic effects of an Angiopoietin-1 mimetic peptide in middle-aged rats with vascular dementia. [PDF]

Front Aging Neurosci, 2023
Gao H, Findeis EL, Culmone L, Powell B, Landschoot-Ward J, Zacharek A, Wu T, Lu M, Chopp M, Venkat P.   +9 more
europepmc   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Ultrasound-guided renal artery administration of angiopoietin-1 RNA therapy slows the progression of preclinical WT1 glomerular disease. [PDF]

Sci Transl Med
Malik SN, Chandler JC, Maeshima R, Kolatsi-Joannou M, Mason WJ, Russell LG, Han S, Harfouche Y, Jafree DJ, Moore EAE, Gautier H, Katsiva C, Al-Saadi R, Pritchard-Jones K, Stuckey DJ, Benest AV, Bates DO, Winyard PJ, Waters AM, Gnudi L, Hart SL, Kalber TL, Long DA.   +22 more
europepmc   +1 more source

Angiopoietin-1 promotes triple-negative breast cancer cell proliferation by upregulating carboxypeptidase A4. [PDF]

Acta Biochim Biophys Sin (Shanghai), 2023
Liu X, Liang H, Fang H, Xiao J, Yang C, Zhou Z, Feng J, Chen C.   +7 more
europepmc   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Newly-engineered angiopoietin-1 as a cell-priming agent for CVD. [PDF]

Cell Mol Life Sci
Kang J, Seo HJ, Son H, Kang M, Lee J, Lee EJ, Cho HJ, Kim HS.   +7 more
europepmc   +1 more source

Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1. [PDF]

Crit Care, 2023
Atreya MR, Cvijanovich NZ, Fitzgerald JC, Weiss SL, Bigham MT, Jain PN, Schwarz AJ, Lutfi R, Nowak J, Allen GL, Thomas NJ, Grunwell JR, Baines T, Quasney M, Haileselassie B, Alder MN, Lahni P, Ripberger S, Ekunwe A, Campbell KR, Walley KR, Standage SW.   +21 more
europepmc   +1 more source

Targeting the PI3K/Akt Signaling Pathway: A Promising Therapeutic Strategy to Reduce Cancer Mortality and Overcome Chemoresistance

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aims The phosphatidylinositol 3‐kinase (PI3K)/Akt signaling pathway is a central regulator of cellular properties that are essential for cancer progression, including cellular growth, survival, metabolism, and angiogenesis. Dysregulated PI3K/Akt signaling, often caused by genetic alterations in PIK3CA, loss of PTEN, or the ...
Md Mohiuddin
wiley   +1 more source

A Highly Active Angiopoietin 1 Mimetic Potentiates Angiogenesis in Mouse Models of Choroidal Neovascularization. [PDF]

Transl Vis Sci Technol
Youssif AA, Liu P, Gaczkowski D, Quaggin SE, Jin J, Thomson BR.   +5 more
europepmc   +1 more source