Results 71 to 80 of about 6,404 (202)
Association of angiopoietins and clinical and demographic variables with liver fibrosis in the training set of CHC patients.
Samuel Martín-Vílchez (422702) +9 more
core +1 more source
Lean ZSF1 rats in basic research on heart failure with preserved ejection fraction
Abstract Aims ZSF1 obese rats harbouring two mutant leptin receptor alleles (Leprcp and Leprfa) develop metabolic syndrome and heart failure with preserved ejection fraction (HFpEF), making them a widely used animal model in cardiometabolic research.
Petra Büttner +10 more
wiley +1 more source
Mechanism of action of Caveolae and its impact pathways
As an important component of transcellular pathway, Caveolae enables the transcellular transport of substances without disrupting cellular homeostasis. In kidney, albumin crosses glomerular filtration barrier (GFB) via Caveolae.
Xiu Du +4 more
doaj +1 more source
Role of Angiopoietins and Tie-2 in Diabetic Retinopathy
Objective: The aim of this study was to determine the serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble vascular endothelial tyrosine kinase receptor (Tie-2) and vascular endothelial growth factor (VEGF), in the serum of type 2 ...
Nervana Khalaf +5 more
doaj +1 more source
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
OBJECTIVE: To determine the utility of angiopoietin-1 and angiopoietin-2 as potentially novel biomarkers of morbidity and mortality in patients with severe sepsis. DESIGN: Multicenter longitudinal cohort study.
Hawkes, Michael +25 more
core +1 more source
Angiopoietins: Microvascular modulators with potential roles in glomerular pathophysiology
Angiopoietins are a recently discovered family of growth factors which act on endothelial cells via Tie receptors. They are widely expressed and have essential roles in regulating vascular growth, development, maturation and permeability. Disturbances in
Satchell, SC, Mathieson, PW
core
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
The curse of angiopoietin-2 in ARDS: on stranger TI(E)des
Pulmonary inflammation and vascular leakage are hallmarks of acute respiratory distress syndrome (ARDS), a life-threatening condition, for which there is no specific pharmacologic treatment.
Philipp Kümpers, Alexander Lukasz
doaj +1 more source
Cellular and molecular aspects of diabetic nephropathy; the role of VEGF-A
The prevalence of diabetes mellitus increased during the last century and it is estimated that 45% of the patients are not diagnosed. In South America the prevalence of diabetes and chronic kidney disease (CKD) increased, with a great disparity among the
Katherine Carranza +6 more
doaj +1 more source

