Results 51 to 60 of about 5,344 (155)
CellsAngiopoietin-1 (Ang-1) and its receptor Tie-2 promote vascular integrity and angiogenesis. MicroRNAs (miRNAs) are involved in the regulation of many cellular functions, including endothelial cell (EC) survival, proliferation, and differentiation. Several
Veronica Sanchez +4 more
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Cellular and molecular aspects of diabetic nephropathy; the role of VEGF-A
Nefrología (English Edition), 2015 The prevalence of diabetes mellitus increased during the last century and it is estimated that 45% of the patients are not diagnosed. In South America the prevalence of diabetes and chronic kidney disease (CKD) increased, with a great disparity among the
Katherine Carranza +6 more
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Angiopoietins as Potential Targets in Management of Retinal Disease
Clinical Ophthalmology, 2021 Arshad M Khanani,1,2 Matthew W Russell,3,4 Aamir A Aziz,1,2 Carl J Danzig,5,6 Christina Y Weng,7 David A Eichenbaum,8,9 Rishi P Singh3,4 1Sierra Eye Associates, Reno, NV, USA; 2The University of Nevada, Reno School of Medicine, Reno, NV, USA; 3Center for
Khanani AM +6 more
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Angiopoietins in Diabetic Retinopathy: Current Understanding and Therapeutic Potential
Journal of Diabetes Research, 2019 Diabetic retinopathy (DR) is the commonest cause of blindness in the working-age population of the developed world. The molecular pathophysiology of DR is complex, and a complete spatiotemporal model of the disease is still being elucidated.
Michael Whitehead +4 more
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The Angiopoietin/Tie2 Axis Mediates Malignant Pleural Effusion Formation
Neoplasia: An International Journal for Oncology Research, 2009 PURPOSE: Angiopoietins and their receptor, Tie2, participate in angiogenesis, regulation of vascular permeability, and inflammation, all central to the pathogenesis of malignant pleural effusions (MPEs). In the present study, we aimed to examine the role
Charalampos Moschos +9 more
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Mechanism of action of Caveolae and its impact pathways
Linchuang shenzangbing zazhiAs an important component of transcellular pathway, Caveolae enables the transcellular transport of substances without disrupting cellular homeostasis. In kidney, albumin crosses glomerular filtration barrier (GFB) via Caveolae.
Xiu Du +4 more
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BMC Cell Biology, 2007 Background The lymphatic system complements the blood circulatory system in absorption and transport of nutrients, and in the maintenance of homeostasis.
Kim Harold +5 more
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Angiopoietin-like proteins: a comprehensive look
Frontiers in Endocrinology, 2014 Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date eight ANGPTLs have been discovered, named ANGPLT1 to ANGPLT8.
Gaetano eSantulli
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Tie2 as a novel key factor of microangiopathy in systemic sclerosis
Arthritis Research & Therapy, 2017 Background The angiopoietin(Ang)/Tie2 system is a key regulator of vascular biology. The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth factor (VEGF), hypoxia, and ...
Falk Moritz +6 more
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International journal of ophthalmology, 2014 To determine the effects of laser photocoagulation on serum levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), soluble angiopoietin receptor Tie-2 (Tie-2), Ang-1/Ang-2 ratio and vascular endothelial growth factor (VEGF) in patients with type 2 diabetes mellitus (T2DM) and proliferative diabetic retinopathy (PDR). We also explored the role of the
Qiao-Ying You +3 more
openaire +3 more sources