Results 51 to 60 of about 6,404 (202)

Release of angiopoietins during differentiation of UT7/mpl cells.

, 2013
UT7/mpl cells have been grown for 7 days in the presence of either GM-CSF (Top Panels) or TPO (Middle Panels) and the concentration of Ang-1 and Ang-2 in the culture supernatants was evaluated by a sensitive and specific ELISA assay.
Alessia Petronelli (316705), Germana Castelli (296202), Ernestina Saulle (168702), Elena Coppotelli (316706), Marco Gabbianelli (316707), Simona Coppola (316713), Ornella Morsilli (316708), Ugo Testa (168771), Raffaella Guerriero (316704), Elvira Pelosi (296201), Isabella Spinello (316709)   +10 more
core   +1 more source

Angiogenesis and angiopoietins in human gliomas [PDF]

, 2015
Het hooggradig glioom is een primaire hersentumor met een infauste prognose ondanks de verschillende vormen van therapie die beschikbaar zijn. Net als andere tumoren zijn gliomen in staat de vorming van nieuwe bloedvaten te induceren.
Wagemakers, Michiel; id_orcid, Wagemakers, Michiel   +1 more
core   +18 more sources

The Angiopoietin Signaling Pathway Is Involved in Inflammatory Processes in Hospitalized COVID-19 Patients

Microorganisms, 2023
The viral agent SARS-CoV-2 clearly affects several organ systems, including the cardiovascular system. Angiopoietins are involved in vascular integrity and angiogenesis.
Rachelle P. Mendoza, Amir Momeni, Nayanendu Saha, Juwairiya Arshi, Elmer C. Gabutan, Nichole Alejandro, Alejandro Zuretti, Prem K. Premsrirut, Dimitar B. Nikolov   +8 more
doaj   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

RNA-Seq Analysis of Human Cumulus Cells Identifies Angiogenic Pathways Associated with Infertility

Cells
Non-invasive assessment of oocyte quality remains a challenge in assisted reproductive technology (ART). Through their bidirectional communication with the gamete, cumulus cells (CCs) act as a functional mirror of oocyte competence; however, the specific
Alejandro Baratas, Victoria Pérez-Quiroga, Rosario Planello, Mónica Aquilino, Magdalena Serrano, Moisés de la Casa, Yosu Franco-Iriarte, Rosa Roy   +7 more
doaj   +1 more source

Single‐Nucleus Atlas of Spinal Sarcopenia Patients Reveals Disruption of Quiescent and Regenerative Satellite Cell Niches in Fatty‐Infiltrated Muscle

Advanced Science, EarlyView.
Mechanisms of Fatty Infiltration and Muscle Degeneration. Clinical metadata identified intramuscular fat accumulation as an independent driver of muscle mass decline. Single‐nucleus RNA sequencing of spinal sarcopenia muscle revealed adipogenic reprogramming of fibro‐adipogenic progenitors, satellite‐cell niche disruption, and elevated levels of the ...
Wenkai Wu, Renxian Wang, Dingding Wang, Quanzhong Ren, Ling Wang, Fangfang Duan, Guihe Yang, Ruixuan Yu, Yi Wang, Yingyu Zhang, Zetong Zang, Chuqi Li, Weijia Liu, Wenshuang Zhang, Yi Yuan, Zitong Cheng, Xiaoguang Cheng, Junbo Liang, Yajun Liu   +18 more
wiley   +1 more source

Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

, 2008
The receptor tyrosine kinase Tie2, and its activating ligand Angiopoietin-1 (Ang1), are required for vascular remodelling and vessel integrity, whereas Ang2 may counteract these functions.
Juho Miettinen, Alitalo, Kari, Deutsch, Urban, Mark Winderlich, Koh, Gou Young, Miettinen, Juho, Vestweber, Dietmar, Saharinen, Pipsa, Astrid Nottebaum, Pipsa Saharinen, Urban Deutsch, Eklund, Lauri, Olsen, Bjorn R, Kari Alitalo, Lauri Eklund, Dietmar Vestweber, Andrey Anisimov, Anisimov, Andrey, Gou Young Koh, Riikka Wirkkala, Wirkkala, Riikka, Nottebaum, Astrid, Bjorn R. Olsen, Winderlich, Mark, Olsen, Bjorn R.   +24 more
core   +1 more source

Angiopoietins, vascular endothelial growth factors and secretory phospholipase A2 in heart failure patients with preserved ejection fraction

, 2022
Heart failure (HF) is a growing public health burden, with high prevalence and mortality rates. A proportion of patients with HF have a normal ventricular ejection fraction (EF), referred to as HF with preserved EF (HFpEF), as opposed to patients with HF
Varricchi, Gilda, Marone, Gianni, Rengo, Giuseppe, Ferrara, Anne Lise, Loffredo, Stefania, Poto, Remo, Bencivenga, Leonardo, Gambino, Giuseppina   +7 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

In vivo actions of angiopoietins on quiescent and remodeling blood and lymphatic vessels in mouse airways and skin

, 2007
Objective-We investigated and compared the in vivo effects of all four angiopoietins (COMP-Ang1, Ang2, Ang3, and Ang4) on blood and lymphatic vascular remodeling in adult mice.
Kim, Kyung Eun, Koh, Gou Young, Kim, Hak-Zoo, Cho, Chung-Hyun, Baluk, Peter, McDonald, Donald M.   +5 more
core   +1 more source