Results 61 to 70 of about 34,611,146 (146)

DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]

, 2012
The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Eisenmenger, Wolfgang, Bondy, Brigitta, Mazza, Marianna, Zill, Peter, Clemens Früstück, Brigitta Bondy, Büttner, Andreas, Born, Christoph, Peter Zill, Andreas Büttner, Varallo-Bedarida, Gabriella, Cornelius Schüle, Früstück, Clemens, Rupprecht, Rainer, Möller, Hans-Jürgen, Schüle, Cornelius, Baghai, Thomas C., Wolfgang Eisenmenger, Christoph Born, Rainer Rupprecht, Hans-Jürgen Möller, Thomas C Baghai, Gabriella Varallo-Bedarida   +22 more
core   +1 more source

Angiotensin-(1-7) is a modulator of the human renin-angiotensin system

, 1999
The renin-angiotensin system is important for cardiovascular homeostasis. Currently, therapies for different cardiovascular diseases are based on inhibition of angiotensin-converting enzyme (ACE) or angiotensin II receptor blockade.
van Gilst, WH, Buikema, H, de Zeeuw, D; id_orcid, Pinto, YM, Henning, RH, van Geel, PP, Roks, AJM   +6 more
core   +2 more sources

Role of the vasodilator peptide angiotensin-(1–7) in cardiovascular drug therapy

, 2007
Christoph Schindler1, Peter Bramlage1, Wilhelm Kirch1, Carlos M Ferrario21Institute of Clinical Pharmacology, Medical Faculty, Technical University of Dresden, Dresden, Germany; 2Hypertension and Vascular Disease Center, Wake Forest University, School of
Carlos M Ferrario, Christoph Schindler, Wilhelm Kirch, Peter Bramlage   +3 more
core  

Reverse translation of phase I biomarker findings links the activity of angiotensin-(1–7) to repression of hypoxia inducible factor-1α in vascular sarcomas

BMC Cancer, 2012
Background In a phase I study of angiotensin-(1–7) [Ang-(1–7)], clinical benefit was associated with reduction in plasma placental growth factor (PlGF) concentrations. The current study examines Ang-(1–7) induced changes in biomarkers according to cancer
Petty W, Aklilu Mebea, Varela Victor A, Lovato James, Savage Paul D, Miller Antonius A   +5 more
doaj   +1 more source

Angiotensin-converting enzyme genotype and late respiratory complications of mustard gas exposure [PDF]

, 2008
Exposure to mustard gas frequently results in long-term respiratory complications. However the factors which drive the development and progression of these complications remain unclear.
Julian Thompson, Nicholas S Hopkinson, Anthony Kehoe, Hopkinson, NS, Humphries, SE, Mostafa Ghanei, Montgomery Hugh, Khoshbaten, A, Hopkinson Nicholas S, Soroush, MR, Hugh Montgomery, Thompson Julian, Hosseini-Khalili, AR, Steve E Humphries, Kehoe, A, Montgomery, H, Ghanei, M, Kehoe Anthony, Hosseini-khalili Ali, Khoshbaten A, A Khoshbaten, Mohammad Reza Soroush, Soroush Mohammad, Thompson, J, Humphries Steve E, Ghanei Mostafa, Ali Reza Hosseini-khalili   +26 more
core   +2 more sources

Angiotensin‐converting enzyme 2 deficiency accelerates and angiotensin 1‐7 restores age‐related muscle weakness in mice

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background A pharmacologic strategy for age‐related muscle weakness is desired to improve mortality and disability in the elderly. Angiotensin‐converting enzyme 2 (ACE2) cleaves angiotensin II into angiotensin 1‐7, a peptide known to protect against ...
Hikari Takeshita, Koichi Yamamoto, Satoko Nozato, Masao Takeda, So‐ichiro Fukada, Tadakatsu Inagaki, Hirotsugu Tsuchimochi, Mikiyasu Shirai, Yoichi Nozato, Taku Fujimoto, Yuki Imaizumi, Serina Yokoyama, Motonori Nagasawa, Go Hamano, Kazuhiro Hongyo, Tatsuo Kawai, Hiroko Hanasaki‐Yamamoto, Shuko Takeda, Toshimasa Takahashi, Hiroshi Akasaka, Norihisa Itoh, Yoichi Takami, Yasushi Takeya, Ken Sugimoto, Hironori Nakagami, Hiromi Rakugi   +25 more
doaj   +1 more source

Angiotensin-converting enzyme 2 and its potential protective effect upon heart

Archives of Medicine and Health Sciences, 2018
To circumvent the major threats of low blood volume and low blood pressure, animals need powerful mechanisms for salt and water conservation, which is renin–angiotensin system (RAS).
Leta Melaku
doaj   +1 more source

Role of Nonclassical Renin-angiotensin system Axis In Renal Fibrosis

Frontiers in Physiology, 2015
The renin–angiotensin system (RAS) is a major regulator of renal fibrosis. Besides the classical renin/Angiotensin-converting enzyme 2 (ACE2)/angiotensin II (Ang II)/AT1 and AT2 axis, multiple new axes have been recently described.
Linli eLv, Bi-Cheng eLiu
doaj   +1 more source

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس, پناهپور, حمداله   +1 more
core   +1 more source

Therapeutic uses for Angiotensin-(1-7)

, 2016
Angiotensin-(1-7) is a key component of the Renin-Angiotensin System, which can counter-regulate several deleterious effects caused by angiotensin II. Due to the potential for therapeutic use, several of its actions are specifically described in patents.
Sinisterra, Rubén Dario, Passos-Silva, Danielle, Machado-Silva, Alice, Santos, Robson Augusto   +3 more
core   +1 more source