Results 51 to 60 of about 34,611,146 (146)
Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue. [PDF]
PLoS ONE, 2017 Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1-7 and alamandine are heptameric renin angiotensin system peptide hormones.
Tsuyoshi Uchiyama +5 more
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Regulation of the renal proximal tubule second sodium pump by angiotensins
Brazilian Journal of Medical and Biological Research, 2001 For several years it was believed that angiotensin II (Ang II) alone mediated the effects of the renin-angiotensin system. However, it has been observed that other peptides of this system, such as angiotensin-(1-7) (Ang-(1-7)), present biological ...
C. Caruso-Neves +3 more
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Evaluation of analgesic activity of perindopril in albino mice
Journal of Advanced Pharmaceutical Technology & Research, 2014 The aim was to evaluate the analgesic activity of perindopril in chemical, thermal and mechanical pain on Swiss albino mice. A total of 54 albino mice (Swiss strain) weighing 25-30 g were allocated to each experimental model and in each model there were ...
R N Suresha +5 more
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BiomedicinesCurrently, cardiovascular diseases are a major contributor to morbidity and mortality worldwide, having a significant negative impact on both the economy and public health.
Janette Alejandra Gamiño-Gutiérrez +10 more
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Enhanced expression of Ang-(1-7) during pregnancy
Brazilian Journal of Medical and Biological Research, 2004 Pregnancy is a physiological condition characterized by a progressive increase of the different components of the renin-angiotensin system (RAS). The physiological consequences of the stimulated RAS in normal pregnancy are incompletely understood, and ...
Brosnihan K.B. +5 more
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An orally active formulation of angiotensin-(1-7) produces an antithrombotic effect
Clinics, 2011 INTRODUCTION AND OBJECTIVE: The heptapeptide angiotensin-(1-7) is a component of the renin-angiotensin system, which promotes many beneficial cardiovascular effects, including antithrombotic activity. We have recently shown that the antithrombotic effect
Rodrigo Araujo Fraga-Silva +6 more
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Modulation of the renin-angiotensin system against COVID-19: A path forward?
International Journal of Infectious DiseasesSoon after the pandemic outbreak in 2020, it was proposed that binding of SARS-CoV-2 to the angiotensin converting enzyme-2 may explain most of COVID-19’s manifestations.
Serge Camelo +11 more
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Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension
Molecules, 2018 The renin-angiotensin-aldosterone system (RAAS) is a dominant player in several cardiovascular pathologies. This study investigated whether alterations induced by l-NAME, (NLG)-nitro-l-arginine methyl ester, a nitric oxide synthase inhibitor, and the ...
Fedor Simko +9 more
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, 2009 The in vivo efficacy of many therapeutic peptides is hampered by their rapid proteolytic degradation. Cyclization of these therapeutic peptides is an excellent way to render them more resistant against breakdown.
Walther, Thomas +9 more
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Peran Angiotensin 1-7 pada Penyakit Ginjal Kronik
Jurnal Ilmu Kesehatan IndonesiaLatar Belakang: Penyakit ginjal kronik (PGK) ditandai penurunan progresif fungsi ginjal. Pada patogenesisnya, sistem renin–angiotensin–aldosteron (RAAS) berperan sentral.
Dinda Putri Sofiani, Harnavi Harun
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