Results 31 to 40 of about 311,191 (157)

Renin-Angiotensin-Aldosterone System in Heart Failure: Focus on Nonclassical Angiotensin Pathways as Novel Upstream Targets Regulating Aldosterone [PDF]

, 2019
Aldosterone plays an important role in the regulation of blood pressure, body fluid, and electrolyte homeostasis. Overactivation of aldosterone/mineralocorticoid receptor (MR) pathway leads to hypertension, atherosclerosis, vascular damage, heart failure,
Mariola Olkowicz, Urszula Tyrankiewicz, Chłopicki, Stefan, Olkowicz, Mariola, Smolenski, Ryszard T., Ryszard T. Smolenski (7951544), Agnieszka Kij, Tyrankiewicz, Urszula, Mariola Olkowicz (3189765), Stefan Chlopicki, Stefan Chlopicki (522371), Urszula Tyrankiewicz (7951541), Mohaissen, Tasnim, Ryszard T. Smolenski, Kij, Agnieszka, Tasnim Mohaissen, Agnieszka Kij (761459), Tasnim Mohaissen (5078378)   +17 more
core   +1 more source

Ang-(1–7) protects skeletal muscle function in aged mice

BMC Musculoskeletal Disorders, 2021
Background The angiotensin-converting enzyme 2 (ACE2)/angiotensin 1–7 (Ang-(1–7)) axis has been shown to protect against the age-associated decline in skeletal muscle function.
Ying Li, Jiao Song, Yangyang Jiang, Xue Yang, Li Cao, Chun Xiao, Suli Li, Birong Dong, Xiaoli Huang   +8 more
doaj   +1 more source

Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla

, 2010
AIMS: Angiotensin(1-7) (Ang1-7) acting at the level of the rostral ventrolateral medulla (RVLM) affects arterial pressure. The cellular substrate of Ang1-7 remains unknown.
Tang, F, Fang Guo, Feige Tang, Samantha Lane, Souslova, E A, Ekaterina A. Souslova, Paton, JFR, Lane, S, Sergey Kasparov, Dmitriy M. Chudakov, Kasparov, S, Guo, F, Chudakov, D M, Liu, B, Beihui Liu, Julian F.R. Paton   +15 more
core   +1 more source

The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]

, 2005
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Lee, A.J., Smith Judith A, Lee, Alison J., Shirras Alan D, Shirras, A.D., Smith, Judith A., Isaac, R.E., Shirras, Alan D., Isaac R Elwyn, Burnham Susan, Smith, J.A., Burnham, Susan, Burnham, S., Lee Alison J, Isaac, R. Elwyn   +14 more
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Classical and Alternative Pathways of the Renin–Angiotensin–Aldosterone System in Regulating Blood Pressure in Hypertension and Obese Adolescents

Biomedicines
Primary hypertension (PH) is the leading form of arterial hypertension (AH) in adolescents. Hypertension is most common in obese patients, where 20 to 40% of the population has elevated blood pressure.
Adrian Martyniak, Dorota Drożdż, Przemysław J. Tomasik   +2 more
doaj   +1 more source

Role of protein kinase C in renal vasoconstriction caused by angiotensin II [PDF]

, 1990
In this study we have examined the subcellar pathways along which angiotensin II (ANG II) causes renal vasoconstriction. Using the isolated perfused rat kidney model, we found that renal vasoconstriction produced by ANG II (100 pM) was not altered by the
Kurtz, Armin, Scholz, H., A. Kurtz, H. Scholz   +3 more
core   +1 more source

Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]

, 2005
Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
core   +1 more source

Angiotensin-(1-7)-Mediated Signaling in Cardiomyocytes

International Journal of Hypertension, 2012
The Renin-Angiotensin System (RAS) acts at multiple targets and has its synthesis machinery present in different tissues, including the heart. Actually, it is well known that besides Ang II, the RAS has other active peptides.
Enéas R. M. Gomes, Robson A. S. Santos, Silvia Guatimosim   +2 more
doaj   +1 more source

Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias [PDF]

, 2006
Background Inappropriate activation of the renin-angiotensin system may play a part in the development of preeclampsia. An insertion/deletion polymorphism within the angiotensin-I converting enzyme gene (ACE-I/D) has shown to be reliably associated with ...
Casas Juan P, Luis A Díaz, Páez, Maria C, Mesa, Clara M, Aroon D Hingorani, Rodrigo Cifuentes, Hingorani, AD, Gonzalez, A, Serrano Norma C, Serrano, Norma C, Monterrosa Alvaro, González, Adriana, Diaz, LA, Serrano, NC, Norma C Serrano, Smeeth, L, Mesa, CM, Monterrosa, Alvaro, Páez Maria C, Cifuentes, Rodrigo, Juan P Casas, Hingorani Aroon D, Díaz Luis A, Smeeth Liam, Mesa Clara M, Casas, Juan P, Adriana González, Díaz, Luis A, Liam Smeeth, González Adriana, Paez, MC, Cifuentes, R, Smeeth, Liam, Casas, JP, Alvaro Monterrosa, Hingorani, Aroon D, Maria C Páez, Cifuentes Rodrigo, Monterrosa, A, Clara M Mesa   +39 more
core   +1 more source

Urgent need for evaluating agonists of angiotensin-(1-7)/Mas receptor axis for treating patients with COVID-19

International Journal of Infectious Diseases, 2020
ACE2 is a receptor of entry of SARS-CoV-2 into the host cells, and its upregulation has been implicated in increasing susceptibility of individuals to this infection.
Ashwini Shete
doaj   +1 more source