Results 11 to 20 of about 311,191 (157)
Antihypertensive effects of angiotensin-(1-7) [PDF]
Brazilian Journal of Medical and Biological Research, 1998 Accumulating evidence suggests that angiotensin-(1-7) (Ang-(1-7)) is an important component of the renin-angiotensin system and that the actions of the peptide may either contribute to or oppose those of Ang II.
M.C. Chappell +3 more
doaj +2 more sources
Cardiovascular actions of angiotensin-(1-7)
Brazilian Journal of Medical and Biological Research, 2005 Angiotensin-(1-7) (Ang-(1-7)) is now considered to be a biologically active member of the renin-angiotensin system. The functions of Ang-(1-7) are often opposite to those attributed to the main effector component of the renin-angiotensin system, Ang II ...
Ferreira A.J., Santos R.A.S.
doaj +1 more source
Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system
Frontiers in Endocrinology, 2022 The local Renin-Angiotensin System (RAS) has been demonstrated to exist in a wide range of tissues and organs, In the female reproductive system, it is mainly found in the ovary, uterus and placenta.
Yuanyuan Liu +8 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2021 Background Little is known about the effect of renin angiotensin aldosterone system‐inhibiting (RAASi) drugs on alternative angiotensin peptides (APs) such as angiotensin 1‐7 (Ang1‐7), which are mediated by angiotensin‐converting enzyme 2 (ACE2 ...
Terry Huh +3 more
doaj +1 more source
Pharmaceuticals, 2022 Rheumatoid arthritis (RA) is a chronic inflammatory condition of synovial joints that causes disability and systemic complications. Ang-(1-7), one of the main peptides in the renin-angiotensin (Ang) system (RAS), imposes its protective effects through ...
Sana Khajeh pour +3 more
doaj +1 more source
Angiotensin 1‐7 protects against ventilator‐induced diaphragm dysfunction
Clinical and Translational Science, 2021 Mechanical ventilation (MV) is a life‐saving instrument used to provide ventilatory support for critically ill patients and patients undergoing surgery.
Toshinori Yoshihara +5 more
doaj +1 more source
Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin Type 2 receptor [PDF]
, 2012 The counter-regulatory axis of the renin angiotensin system peptide angiotensin-(1-7) [Ang-(1-7)] has been identified as a potential therapeutic target in cardiac remodelling, acting via the mas receptor.
Nicklin Stuart A. +11 more
core +1 more source
Electronic sculpting of ligand-GPCR subtype selectivity:the case of angiotensin II [PDF]
, 2014 GPCR subtypes possess distinct functional and pharmacological profiles, and thus development of subtype-selective ligands has immense therapeutic potential.
Pappas, Charalampos G. +41 more
core +1 more source
Journal of Veterinary Internal Medicine, 2021 Background The pathophysiology of heart failure involves maladaptive angiotensin peptides (APs) and enzymes, including angiotensin 2 (AT2) and angiotensin converting enzyme (ACE), as well as recently described alternative components, such as angiotensin ...
Éva Larouche‐Lebel +3 more
doaj +1 more source
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy [PDF]
, 2007 Maternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor.
Kellems, Rodney E. +19 more
core +1 more source