Results 21 to 30 of about 311,191 (157)
Neural Regeneration Research, 2022 Abnormal accumulation of α-synuclein contributes to the formation of Lewy bodies in the substantia nigra, which is considered the typical pathological hallmark of Parkinson’s disease.
Qing Gao +6 more
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Renin-Angiotensin System: A Review of Historical Perspectives
Galician Medical Journal, 2023 The article is a review of publications concerning historical perspectives of the renin-angiotensin system. The discovery of its components is presented in chronological order, beginning with the initial identification of renin and proceeding to the ...
Olga Kovalyova +2 more
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Intensive Care Medicine Experimental, 2019 Background Ventilator-induced diaphragmatic dysfunction (VIDD) is a common event during mechanical ventilation (MV) leading to rapid muscular atrophy and contractile dysfunction. Recent data show that renin-angiotensin system is involved in diaphragmatic
Vanessa Zambelli +7 more
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The Role of Renin–Angiotensin System in Diabetic Cardiomyopathy: A Narrative Review
Life, 2023 Diabetic cardiomyopathy refers to myocardial dysfunction in type 2 diabetes, but without the traditional cardiovascular risk factors or overt clinical atherosclerosis and valvular disease.
João Pedro Thimotheo Batista +3 more
doaj +1 more source
Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo [PDF]
, 2004 <b>Background</b> From in vitro studies, it has become clear that several signaling cascades are involved in angiotensin II-induced cellular hypertrophy.
Martens Fabrice MAC +23 more
core +1 more source
Renal actions of angiotensin-(1-7)
Brazilian Journal of Medical and Biological Research, 1997 The heptapeptide angiotensin-(1-7) is considered to be a biologically active endproduct of the renin-angiotensin system. This angiotensin, which is devoid of the most known actions of angiotensin II such as induction of drinking behavior and ...
A.C. Simões-e-Silva +3 more
doaj +1 more source
Biomolecules, 2021 Renin–angiotensin systems produce angiotensin II (Ang II) and angiotensin 1-7 (Ang 1-7), which are able to induce opposite effects on circulation. This study in vivo assessed the effects induced by Ang II or Ang 1-7 on rat pial microcirculation during ...
Dominga Lapi +14 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2015 Background/Aims: Atherosclerosis is a chronic inflammatory disease. Intracellular adhesion molecule-1 (ICAM-1), vascular cellular adhesion molecule-1 (VCAM-1), and monocyte chemoattractant protein-1 (MCP-1) play important roles in inflammatory processes.
Bin Liang +8 more
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A New Perspective on the Renin-Angiotensin System
Diagnostics, 2022 Cardiovascular disease (CVD) is the leading cause of death in the world. Hypertension is a serious medical problem not only in adults but also in children and adolescents.
Adrian Martyniak, Przemysław J. Tomasik
doaj +1 more source
Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2 [PDF]
, 2009 Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is great interest in the therapeutic benefit for ACE2 overexpression in the heart.
Smith, Godfrey +12 more
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