Results 41 to 50 of about 311,191 (157)

Angiotensin-(1-7) and Mas receptor in the brain

Exploration of Medicine, 2021
The renin-angiotensin system (RAS) is a key regulator of blood pressure and electrolyte homeostasis. Besides its importance as regulator of the cardiovascular function, the RAS has also been associated to the modulation of higher brain functions ...
Natalia L. Rukavina Mikusic, Angélica M. Pineda, Mariela M. Gironacci   +2 more
doaj   +1 more source

Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation

Frontiers in Physiology, 2017
Background and Aims: The angiotensin-(1-7)/angiotensin-converting enzyme 2/Mas receptor axis counter-regulates the detrimental effects of angiotensin II.
Wan-Yu Pai, Wan-Yu Lo, Todd Hsu, Ching-Tien Peng, Ching-Tien Peng, Huang-Joe Wang, Huang-Joe Wang, Huang-Joe Wang   +7 more
doaj   +1 more source

Effect of olmesartan and amlodipine on serum angiotensin-(1–7) levels and kidney and vascular function in patients with type 2 diabetes and hypertension

Diabetology & Metabolic Syndrome, 2023
Background Recent studies suggest that angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1–7) [Ang-(1–7)] might have beneficial effects on the cardiovascular system.
Kyuho Kim, Ji Hye Moon, Chang Ho Ahn, Soo Lim   +3 more
doaj   +1 more source

Does angiotensin-1 converting enzyme genotype influence motor or cognitive development after pre-term birth?

, 2005
Background Raised activity of the renin-angiotensin system (RAS) may both amplify inflammatory and free radical responses and decrease tissue metabolic efficiency and thus enhance cerebral injury in the preterm infant.
Montgomery, H, Harding, DR, Devadason David, Humphries, S, Whitelaw, A, David Davedason, Marlow Neil, Montgomery Hugh E, Marlow, N, Hugh E Montgomery, Davedason, D, Andrew Whitelaw, Humphries, SE, Neil Marlow, Montgomery, HE, Whitelaw Andrew, Humphries Steve E, Dhamrait Sukhbir, Devadason, D, Dhamrait, S, Steve E Humphries, Harding David R, David R Harding, Sukhbir Dhamrait   +23 more
core   +1 more source

Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin‐Deficient Mice via Upregulation of Angiotensin (1–7)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial.
Kohei Karasaki, Hiroki Kokubo, Batmunkh Bumdelger, Nobuchika Kaji, Chiemi Sakai, Mari Ishida, Masao Yoshizumi   +6 more
doaj   +1 more source

Effects of oral HPΒCD-angiotensin-(1-7) supplementation on recreational mountain bike athletes: a crossover study

, 2023
Supplementation with Angiotensin-(1-7) [(Ang-1-7)] has received considerable attention due to its possible ergogenic effects on physical performance.
Samara Silva de Moura (14650168), Francisco de Assis Dias Martins-Júnior (14650171), Daniel Barbosa Coelho (5890085), Robson Augusto Souza Dos Santos (14650177), Adriano Eduardo Lima-Silva (7823417), Daisy Motta-Santos (483618), Emerson Cruz de Oliveira (14650174), Daniel Boari (7832309), Lenice Kappes Becker (10665543)   +8 more
core   +1 more source

DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]

, 2012
The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Eisenmenger, Wolfgang, Bondy, Brigitta, Mazza, Marianna, Zill, Peter, Clemens Früstück, Brigitta Bondy, Büttner, Andreas, Born, Christoph, Peter Zill, Andreas Büttner, Varallo-Bedarida, Gabriella, Cornelius Schüle, Früstück, Clemens, Rupprecht, Rainer, Möller, Hans-Jürgen, Schüle, Cornelius, Baghai, Thomas C., Wolfgang Eisenmenger, Christoph Born, Rainer Rupprecht, Hans-Jürgen Möller, Thomas C Baghai, Gabriella Varallo-Bedarida   +22 more
core   +1 more source

Angiotensin-(1-7) is a modulator of the human renin-angiotensin system

, 1999
The renin-angiotensin system is important for cardiovascular homeostasis. Currently, therapies for different cardiovascular diseases are based on inhibition of angiotensin-converting enzyme (ACE) or angiotensin II receptor blockade.
van Gilst, WH, Buikema, H, de Zeeuw, D; id_orcid, Pinto, YM, Henning, RH, van Geel, PP, Roks, AJM   +6 more
core   +2 more sources

Angiotensin-(1-7) with Thioether Bridge: An Angiotensin-Converting Enzyme-Resistant, Potent Angiotensin-(1-7) Analog

, 2009
The in vivo efficacy of many therapeutic peptides is hampered by their rapid proteolytic degradation. Cyclization of these therapeutic peptides is an excellent way to render them more resistant against breakdown.
Walther, Thomas, de Vries, Louwe, Rink, Rick, Moll, Gert N., Kuipers, Anneke, Nelemans, S. Adriaan, Kluskens, Leon D., Meter-Arkema, Anita, Wang, Yong, Haas, Marijke   +9 more
core   +1 more source

Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue. [PDF]

PLoS ONE, 2017
Obesity is associated with an increased risk of diabetes mellitus, hypertension, and renal dysfunction. Angiotensin 1-7 and alamandine are heptameric renin angiotensin system peptide hormones.
Tsuyoshi Uchiyama, Fumikazu Okajima, Chihiro Mogi, Ayaka Tobo, Shoichi Tomono, Koichi Sato   +5 more
doaj   +1 more source