Results 41 to 50 of about 34,611,146 (146)

Urgent need for evaluating agonists of angiotensin-(1-7)/Mas receptor axis for treating patients with COVID-19

International Journal of Infectious Diseases, 2020
ACE2 is a receptor of entry of SARS-CoV-2 into the host cells, and its upregulation has been implicated in increasing susceptibility of individuals to this infection.
Ashwini Shete
doaj   +1 more source

Angiotensin-(1-7) and Mas receptor in the brain

Exploration of Medicine, 2021
The renin-angiotensin system (RAS) is a key regulator of blood pressure and electrolyte homeostasis. Besides its importance as regulator of the cardiovascular function, the RAS has also been associated to the modulation of higher brain functions ...
Natalia L. Rukavina Mikusic, Angélica M. Pineda, Mariela M. Gironacci   +2 more
doaj   +1 more source

Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation

Frontiers in Physiology, 2017
Background and Aims: The angiotensin-(1-7)/angiotensin-converting enzyme 2/Mas receptor axis counter-regulates the detrimental effects of angiotensin II.
Wan-Yu Pai, Wan-Yu Lo, Todd Hsu, Ching-Tien Peng, Ching-Tien Peng, Huang-Joe Wang, Huang-Joe Wang, Huang-Joe Wang   +7 more
doaj   +1 more source

Effect of olmesartan and amlodipine on serum angiotensin-(1–7) levels and kidney and vascular function in patients with type 2 diabetes and hypertension

Diabetology & Metabolic Syndrome, 2023
Background Recent studies suggest that angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1–7) [Ang-(1–7)] might have beneficial effects on the cardiovascular system.
Kyuho Kim, Ji Hye Moon, Chang Ho Ahn, Soo Lim   +3 more
doaj   +1 more source

Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin‐Deficient Mice via Upregulation of Angiotensin (1–7)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Angiotensin II type 1 receptor blockers (ARBs) have been shown to limit the growth of abdominal aortic aneurysm (AAA), but their efficacy is controversial.
Kohei Karasaki, Hiroki Kokubo, Batmunkh Bumdelger, Nobuchika Kaji, Chiemi Sakai, Mari Ishida, Masao Yoshizumi   +6 more
doaj   +1 more source

Role of protein kinase C in renal vasoconstriction caused by angiotensin II [PDF]

, 1990
In this study we have examined the subcellar pathways along which angiotensin II (ANG II) causes renal vasoconstriction. Using the isolated perfused rat kidney model, we found that renal vasoconstriction produced by ANG II (100 pM) was not altered by the
Kurtz, Armin, Scholz, H., A. Kurtz, H. Scholz   +3 more
core   +1 more source

Hepatic Mitochondrial Renin-Angiotensin Systems [PDF]

, 2015
Introduction: The circulating renin-angiotensin system (RAS) was originally described as a key endocrine regulator of intravascular homeostasis; however, the existence of a local (tissue) RAS has become increasingly reported in a variety of tissues ...
Skipworth, JRA
core  

[7-D-ALA]-angiotensin-(1-7): selective antagonism of angiotensin-(1-7) in the rat paraventricular nucleus.

, 1994
Microiontophoretic application of both, the octapeptide angiotensin II (Ang II) and its N-terminal heptapeptide angiotensin-(1-7), [Ang-(1-7)], has been shown to increase the firing rate of rat hypothalamic paraventricular neurones.
Felix D, Ambühl P, Khosla MC
core   +1 more source

Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: Evidence of small-study bias [PDF]

, 2006
Background Inappropriate activation of the renin-angiotensin system may play a part in the development of preeclampsia. An insertion/deletion polymorphism within the angiotensin-I converting enzyme gene (ACE-I/D) has shown to be reliably associated with ...
Casas Juan P, Luis A Díaz, Páez, Maria C, Mesa, Clara M, Aroon D Hingorani, Rodrigo Cifuentes, Hingorani, AD, Gonzalez, A, Serrano Norma C, Serrano, Norma C, Monterrosa Alvaro, González, Adriana, Diaz, LA, Serrano, NC, Norma C Serrano, Smeeth, L, Mesa, CM, Monterrosa, Alvaro, Páez Maria C, Cifuentes, Rodrigo, Juan P Casas, Hingorani Aroon D, Díaz Luis A, Smeeth Liam, Mesa Clara M, Casas, Juan P, Adriana González, Díaz, Luis A, Liam Smeeth, González Adriana, Paez, MC, Cifuentes, R, Smeeth, Liam, Casas, JP, Alvaro Monterrosa, Hingorani, Aroon D, Maria C Páez, Cifuentes Rodrigo, Monterrosa, A, Clara M Mesa   +39 more
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Angiogenesis "in vitro" of the healthy mouse heart under hypoxia : the role of Angiotensin II and Nitric Oxide [PDF]

, 2005
Angiogenesis is the process by which blood microvessels are formed from existing ones. Angiogenesis is required for development. It is also important for reducing myocardial hypoxia due to coronary and ischemic heart disease; in myocardial infarction ...
Munk, Veronica Cecilia
core   +1 more source