Results 41 to 50 of about 655,327 (339)

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

open access: yes, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio   +8 more
core   +1 more source

Treatment of hypertension with angiotensin‐converting enzyme inhibitors or angiotensin receptor blockers and resting metabolic rate: A cross‐sectional study

open access: yesThe Journal of Clinical Hypertension, 2021
Hypertension in obese and overweight patients is associated with an elevated resting metabolic rate (RMR). The aim of this study was to determine whether RMR is reduced in hypertensive patients treated with angiotensin‐converting enzyme inhibitors (ACEI)
Pablo B. Pedrianes‐Martin   +8 more
doaj   +1 more source

The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice [PDF]

open access: yes, 2018
BACKGROUND: The orphan receptor G protein–coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure.
Divorty, Nina   +3 more
core   +1 more source

Mineralocorticoid axis activity and cardiac remodeling in patients with ACTH-dependent Cushing’s syndrome

open access: yesEndocrine Connections
Background: Arterial hypertension and left ventricular hypertrophy and remodeling are independent cardiovascular risk factors in patients with Cushing’s syndrome. Changes in the renin–angiotensin system and in the mineralocorticoid axis activity could be
Peter Wolf   +13 more
doaj   +1 more source

ACE2, Much More Than Just a Receptor for SARS-COV-2

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) has been identified as the receptor for the SARS-CoV-2 viral entry.
Lobelia Samavati   +2 more
doaj   +1 more source

Therapeutic potential of the renin angiotensin system in ischaemic stroke [PDF]

open access: yes, 2016
The renin angiotensin system (RAS) consists of the systemic hormone system, critically involved in regulation and homeostasis of normal physiological functions [i.e.
Arroja, Mariana Moreira Coutinho   +2 more
core   +1 more source

Renin-Angiotensin System [PDF]

open access: yesNew England Journal of Medicine, 1975
ALTHOUGH the names of Tigerstedt and Bergman1 are associated with the first description in 1898 of renin extracted from the kidney, it may come as a surprise that when Tigerstedt, who was the senior worker in the partnership and the Professor of Physiology in the Karolinska Institute, Stockholm, died, there was no mention of renin in the various ...
openaire   +3 more sources

Primary aldosteronism and obstructive sleep apnea: What do we know thus far?

open access: yesFrontiers in Endocrinology, 2022
Both primary aldosteronism and obstructive sleep apnea are well-known causes of hypertension and contribute to increased cardiovascular morbidity and mortality independently.
Huai Heng Loh   +2 more
doaj   +1 more source

Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]

open access: yes, 2018
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L   +4 more
core  

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