Results 11 to 20 of about 4,861,792 (337)

From Angiotensin II to Cyclic Peptides and Angiotensin Receptor Blockers (ARBs): Perspectives of ARBs in COVID-19 Therapy

open access: yesMolecules, 2021
The octapeptide hormone angiotensin II is one of the most studied peptides with the aim of designing and synthesizing non-peptide mimetics for oral administration.
John Matsoukas   +6 more
doaj   +1 more source

Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. A Clinical Trial

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Exogenous angiotensin II increases mean arterial pressure in patients with catecholamine-resistant vasodilatory shock (CRVS). We hypothesized that renin concentrations may identify patients most likely to benefit from such therapy. Objectives:
R. Bellomo   +13 more
semanticscholar   +1 more source

COVID‐19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease

open access: yesEuropean Journal of Heart Failure, 2020
Patients with cardiovascular disease and, namely, heart failure are more susceptible to coronavirus disease 2019 (COVID‐19) and have a more severe clinical course once infected.
D. Tomasoni   +6 more
semanticscholar   +1 more source

Angiotensin‐converting enzyme inhibitors and angiotensin II receptor blockers are not associated with severe COVID‐19 infection in a multi‐site UK acute hospital trust

open access: yesEuropean Journal of Heart Failure, 2020
The SARS‐CoV‐2 virus binds to the angiotensin‐converting enzyme 2 (ACE2) receptor for cell entry. It has been suggested that angiotensin‐converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB), which are commonly used in patients ...
D. Bean   +13 more
semanticscholar   +1 more source

Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]

open access: yesPLoS ONE, 2014
INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand   +4 more
doaj   +1 more source

Angiotensin II facilitates fibrogenic effect of TGF-β1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II. [PDF]

open access: yesPLoS ONE, 2013
Angiotensin II has progressively been considered to play an important role in the development of liver fibrosis, although the mechanism isn't fully understood.
Yu-Sheng Li   +6 more
doaj   +1 more source

Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

open access: yesPhysiological Reviews, 2018
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology and pathophysiology. However, many of the signaling mechanisms have been unclear.
Steven J Forrester   +7 more
semanticscholar   +1 more source

Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling

open access: yesFrontiers in Pharmacology, 2022
Vascular remodeling due to hypertension is one of the major health challenges facing countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an antioxidant.
Jingsi Zhang   +7 more
doaj   +1 more source

Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]

open access: yesPLoS ONE, 2015
Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado   +7 more
doaj   +1 more source

Human Angiotensin II Receptors are Regulated By Angiotensin II

open access: yesClinical and Experimental Hypertension. Part A: Theory and Practice, 1988
Specific angiotensin II (ANG II) binding on human platelets in man was measured to examine ANG II receptor regulation in man. Eight normal volunteers received either a high, or a low sodium diet, or a low sodium diet together with the ANG I converting enzyme inhibitor enalapril.
E. Ritz, M. Leidig, J. F. E. Mann
openaire   +3 more sources

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