Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors. [PDF]
PLoS ONE, 2014 INTRODUCTION: Recently, we could show that angiotensin II, the reactive peptide of the blood pressure-regulating renin-angiotensin-aldosterone-system, causes the formation of reactive oxygen species and DNA damage in kidneys and hearts of hypertensive ...
Susanne Brand +4 more
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Angiotensin II facilitates fibrogenic effect of TGF-β1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II. [PDF]
PLoS ONE, 2013 Angiotensin II has progressively been considered to play an important role in the development of liver fibrosis, although the mechanism isn't fully understood.
Yu-Sheng Li +6 more
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Neohesperidin Protects Angiotensin II-Induced Hypertension and Vascular Remodeling
Frontiers in Pharmacology, 2022 Vascular remodeling due to hypertension is one of the major health challenges facing countries around the world. Neohesperidin, a flavonoid glycoside found in citrus fruits, is an antioxidant.
Jingsi Zhang +7 more
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Current status of liver transplantation for non‐B non‐C liver cirrhosis and hepatocellular carcinoma
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 42-52, January 2023., 2023 Recently, the cases of LT for non‐B non‐C cirrhosis and HCC have been increasing in Japan as well as worldwide. Perioperative management of non‐B non‐C liver disease is problematic due to various risk factors, including alcohol consumption and metabolic syndrome‐related risks, such as obesity and diabetes mellitus.
Takahiro Nishio +4 more
wiley +1 more source
Frontiers in Pharmacology, 2015 Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1-7 ...
Daniel eClayton +6 more
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Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]
PLoS ONE, 2015 Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado +7 more
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Human Angiotensin II Receptors are Regulated By Angiotensin II
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1988 Specific angiotensin II (ANG II) binding on human platelets in man was measured to examine ANG II receptor regulation in man. Eight normal volunteers received either a high, or a low sodium diet, or a low sodium diet together with the ANG I converting enzyme inhibitor enalapril.
E. Ritz, M. Leidig, J. F. E. Mann
openaire +3 more sources
Advance in Research of Angiotensin II and Its Receptor and Malignant Tumor
Chinese Journal of Lung Cancer, 2016 Angiotensin AngII, a linear small peptide,which is composed of eight amino acids, is the main effectors of renin-angiotensin systen (Renin-angiotensin system, RAS).
Lulu SUN, Jian SHI
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Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms [PDF]
St-Pierre D, et al. (2018), Biochem Pharmacol. 154:104-17, 2019 G protein coupled receptors (GPCRs) produce pleiotropic effects by their capacity to engage numerous signaling pathways once activated. Functional selectivity (also called biased signaling), where specific compounds can bring GPCRs to adopt conformations that enable selective receptor coupling to distinct signaling pathways, continues to be ...
arxiv +1 more source
Angiotensin II in septic shock [PDF]
Critical Care, 2015 This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015.
Thiago Domingos Corrêa +2 more
openaire +4 more sources