Results 21 to 30 of about 400,239 (293)

Therapeutic potential of the renin angiotensin system in ischaemic stroke [PDF]

, 2016
The renin angiotensin system (RAS) consists of the systemic hormone system, critically involved in regulation and homeostasis of normal physiological functions [i.e.
Arroja, Mariana Moreira Coutinho, McCabe, Christopher, Reid, Emma   +2 more
core   +1 more source

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors

Frontiers in Pharmacology, 2015
Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1-7 ...
Daniel eClayton, Iresha eHanchapola, Walter Glen Thomas, Robert eWiddop, Alexander Ian Smith, Patrick ePerlmutter, Marie-Isabel eAguilar   +6 more
doaj   +1 more source

Angiotensin II as an Inducer of Atherosclerosis: Evidence from Mouse Studies [PDF]

, 2013
Mechanisms responsible for atherosclerotic plaque development, destabilization, and rupture are still largely unknown. Angiotensin II, the main bioactive peptide of renin angiotensin system, has been shown to be critically involved in the pathogenesis of
Mazzolai, L., Pellegrin, M.
core   +1 more source

Annihilator Banach ∗-algebras and the Peter-Weyl theorem [PDF]

, 1976
The QUO VADIS (the effects of QUinapril On Vascular Ace and Determinants of ISchemia) study was a randomized, double-blind, placebo-controlled trial designed to evaluate the effects of long-term angiotensin-converting enzyme (ACE) inhibition on ...
Dennis Wildfogel, Barnes, Barnes, Barnes, Dixmier, Halmos, Hewitt, Kaplansky, Loomis, Naimark, Rickart, Wildfogel, Wildfogel, Yood, Yood, Yood   +15 more
core   +2 more sources

Pathological Role of Angiotensin II in Severe COVID-19

TH Open, 2020
The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
doaj   +1 more source

Hubungan Polimorfisme Gen Reseptor Angiotensin II Tipe 1 1166 A/C dengan Kejadian Preeklampsia [PDF]

, 2014
Latar Belakang:Preeklampsia adalah kelainan multisistem spesifik pada kehamilan yang ditandai oleh timbulnya hipertensi dan protein uria setelah umur kehamilan 20 minggu.
Hayati, L. (Lusia), Rahmadhayanti, E. (Eka), Saleh, M. I. (Mgs)   +2 more
core   +2 more sources

Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice [PDF]

, 2003
Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension.
Aubert, Busetto, Butz, Christopher J. Kenyon, Contreras, Cowley, De la Sieera, Folli, Frederich, Hiroaki Masuzaki, Hiroshi Shinyama, Hiroshi Yamamoto, Janice M. Paterson, Jeffrey S. Flier, Joel K. Elmquist, John J. Mullins, Johnson, Jonathan R. Seckl, Kopelman, Lalouel, Llorens-Cortes, Massiera, Masuzaki, Matthew G.F. Sharp, Miller, Mills, Montani, Morton, Nicholas M. Morton, O’Brien, Pradevand, Pratt, Rotimi, Stepp, Stewart Fleming, Villiquette, Walker, Weinburger, Williams, Yamamoto   +39 more
core   +6 more sources

Vascular smooth muscle Sirtuin-1 protects against aortic dissection during Angiotensin II-induced hypertension [PDF]

, 2015
BACKGROUND: Sirtuin-1 (SirT1), a nicotinamide adenine dinucleotide(+)-dependent deacetylase, is a key enzyme in the cellular response to metabolic, inflammatory, and oxidative stresses; however, the role of endogenous SirT1 in the vasculature has not ...
Akiki, Rachid, Bachschmid, Markus, Cohen, Richard A., Fry, Jessica L., Gao, Yuan Z., Morgan, Kathleen G., Seta, Francesca, Shiraishi, Yasunaga, Turcotte, Raphaël, Yu, Xunjie, Zhang, Yanhang   +10 more
core   +1 more source

Maternal plasma angiotensin 1-7 concentration is related to twin pregnancy chorionicity in the third trimester of pregnancy

Frontiers in Endocrinology
IntroductionTwin gestation is related to a higher risk of hypertensive disorders in pregnancy with possible risk stratification depending on chorionicity.
Paweł Pietruski, Katarzyna Kosińska-Kaczyńska, Agnieszka Osińska, Magdalena Zgliczyńska, Kinga Żebrowska, Katarzyna Popko, Anna Stelmaszczyk-Emmel   +6 more
doaj   +1 more source

Mass-spectrometric identification of a novel angiotensin peptide in human plasma [PDF]

, 2007
Objective— Angiotensin peptides play a central role in cardiovascular physiology and pathology. Among these peptides, angiotensin II (Ang II) has been investigated most intensively.
Bader, Michael, Beyermann, Michael, Furkert, Jens, Gobom, Johan, Jankowski, Joachim, Jankowski, Vera, Karadogan, Sevil, Krause, Eberhard, Oksche, Alexander, Schlüter, Hartmut, Schuchardt, Mirjam, Tepel, Martin, Todiras, Mihail, Tran, Thi Nguyet Anh, Tölle, Markus, van der Giet, Markus, Vanholder, Raymond, Wiedon, Annette, Zidek, Walter   +18 more
core   +1 more source