Angiotensin II facilitates fibrogenic effect of TGF-β1 through enhancing the down-regulation of BAMBI caused by LPS: a new pro-fibrotic mechanism of angiotensin II. [PDF]
PLoS ONE, 2013 Angiotensin II has progressively been considered to play an important role in the development of liver fibrosis, although the mechanism isn't fully understood.
Yu-Sheng Li +6 more
doaj +1 more source
Vascular smooth muscle Sirtuin-1 protects against aortic dissection during Angiotensin II-induced hypertension [PDF]
, 2015 BACKGROUND: Sirtuin-1 (SirT1), a nicotinamide adenine dinucleotide(+)-dependent deacetylase, is a key enzyme in the cellular response to metabolic, inflammatory, and oxidative stresses; however, the role of endogenous SirT1 in the vasculature has not ...
Akiki, Rachid +10 more
core +1 more source
Human Angiotensin II Receptors are Regulated By Angiotensin II
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1988 Specific angiotensin II (ANG II) binding on human platelets in man was measured to examine ANG II receptor regulation in man. Eight normal volunteers received either a high, or a low sodium diet, or a low sodium diet together with the ANG I converting enzyme inhibitor enalapril.
E. Ritz, M. Leidig, J. F. E. Mann
openaire +3 more sources
Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms [PDF]
St-Pierre D, et al. (2018), Biochem Pharmacol. 154:104-17, 2019 G protein coupled receptors (GPCRs) produce pleiotropic effects by their capacity to engage numerous signaling pathways once activated. Functional selectivity (also called biased signaling), where specific compounds can bring GPCRs to adopt conformations that enable selective receptor coupling to distinct signaling pathways, continues to be ...
arxiv +1 more source
Advance in Research of Angiotensin II and Its Receptor and Malignant Tumor
Chinese Journal of Lung Cancer, 2016 Angiotensin AngII, a linear small peptide,which is composed of eight amino acids, is the main effectors of renin-angiotensin systen (Renin-angiotensin system, RAS).
Lulu SUN, Jian SHI
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundThe significance of brain angiotensin II in Alzheimer disease (AD) is unclear. Methods and ResultsTo examine the role of brain angiotensin II in AD, intracerebroventricular angiotensin II infusion was performed on 5XFAD mice, a mouse model of ...
Koki Takane +6 more
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Atypical angiotensin II receptors coupled to phosphoinositide turnover/calcium signalling in catfish hepatocytes [PDF]
, 1997 In catfish (Ictalurus punctatus) hepatocytes angiotensin II induced an immediate increase in cytosolic Ca2+ concentration. Other angiotensin analogues also induced this effect including: human angiotensin II, fish angiotensin II, human angiotensin III ...
Garcı́a-Sáinz, J.Adolfo +2 more
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Angiotensin II in septic shock [PDF]
Critical Care, 2015 This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015.
Thiago Domingos Corrêa +2 more
openaire +4 more sources
Conversion and degradation of [125I] labelled angiotensin I in isolated perfused porcine coronary and carotid arteries [PDF]
, 1994 The aims were (1) to quantitate angiotensin I to II conversion on the endothelial surface and at deeper sites in isolated arteries, (2) to assess whether the angiotensin II that is formed at deeper sites is released into the vascular lumen, and (3) to ...
Chowdury, S. (Suchandana) +5 more
core +1 more source
Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice [PDF]
, 2003 Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension.
Aubert +39 more
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