Results 21 to 30 of about 4,861,792 (337)

Advance in Research of Angiotensin II and Its Receptor and Malignant Tumor

open access: yesChinese Journal of Lung Cancer, 2016
Angiotensin AngII, a linear small peptide,which is composed of eight amino acids, is the main effectors of renin-angiotensin systen (Renin-angiotensin system, RAS).
Lulu SUN, Jian SHI
doaj   +1 more source

Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe significance of brain angiotensin II in Alzheimer disease (AD) is unclear. Methods and ResultsTo examine the role of brain angiotensin II in AD, intracerebroventricular angiotensin II infusion was performed on 5XFAD mice, a mouse model of ...
Koki Takane   +6 more
doaj   +1 more source

Angiotensin II in septic shock [PDF]

open access: yesCritical Care, 2015
This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2015 and co-published as a series in Critical Care. Other articles in the series can be found online at http://ccforum.com/series/annualupdate2015.
Thiago Domingos Corrêa   +2 more
openaire   +4 more sources

Angiotensin II induces cholesterol accumulation and impairs insulin secretion by regulating ABCA1 in beta cells

open access: yesJournal of Lipid Research, 2018
In pancreatic β cells, ABCA1, a 254 kDa membrane protein, affects cholesterol homeostasis and insulin secretion. Angiotensin II, as the main effector of the renin–angiotensin system, decreases glucose-stimulated insulin secretion (GSIS).
Jingya Lyu   +11 more
doaj   +1 more source

Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent.

open access: yesHYPERTENSION, 2019
The Ang II (Angiotensin II)-Angiotensin-(1-7) axis of the Renin Angiotensin System encompasses 3 enzymes that form Angiotensin-(1-7) [Ang-(1-7)] directly from Ang II: ACE2 (angiotensin-converting enzyme 2), PRCP (prolylcarboxypeptidase), and POP ...
P. Serfozo   +11 more
semanticscholar   +1 more source

Angiotensin II and Renal Fibrosis [PDF]

open access: yesHypertension, 2001
Abstract — — Angiotensin (Ang) II, the main peptide of the renin angiotensin system (RAS), is a renal growth factor, inducing hyperplasia/hypertrophy depending on the cell type. This vasoactive peptide activates mesangial and tubular cells and interstitial fibroblasts, increasing the ...
Mezzano, SA, Ruiz-Ortega, M, Egido, J
openaire   +5 more sources

Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors

open access: yesFrontiers in Pharmacology, 2015
Angiotensin converting enzyme 2 (ACE2) is a zinc carboxypeptidase involved in the renin angiotensin system (RAS) and inactivates the potent vasopressive peptide angiotensin II (Ang II) by removing the C-terminal phenylalanine residue to yield Ang1-7 ...
Daniel eClayton   +6 more
doaj   +1 more source

The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors

open access: yesBrazilian Journal of Medical and Biological Research, 1998
We have shown that the renin-angiotensin system (RAS) is involved in glucose homeostasis during acute hemorrhage. Since almost all of the physiological actions described for angiotensin II were mediated by AT1 receptors, the present experiments were ...
L.J.C. Machado   +3 more
doaj   +1 more source

Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II

open access: yesCritical Care Medicine, 2018
Objective: Acute kidney injury requiring renal replacement therapy in severe vasodilatory shock is associated with an unfavorable prognosis. Angiotensin II treatment may help these patients by potentially restoring renal function without decreasing ...
J. Tumlin   +18 more
semanticscholar   +1 more source

Analysis of the Vasorelaxant Action of Angiotensin II in the Isolated Rat Renal Artery

open access: yesJournal of Pharmacological Sciences, 2008
Taking into consideration that mechanisms involved in the vasodilatator actions of angiotensin II have not yet been completely elucidated, the present study was undertaken in order to examine the mechanisms underlying the angiotensin II–induced ...
Leposava Grbović   +3 more
doaj   +1 more source

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