In Vitro Killing Activities of Anidulafungin and Micafungin with and without Nikkomycin Z against Four Candida auris Clades [PDF]
Pharmaceutics, 2023 Candida auris is a multidrug-resistant pathogen against which echinocandins are the drug of choice. However, information on how the chitin synthase inhibitor nikkomycin Z influences the killing activities of echinocandins against C.
Awid Adnan +9 more
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Post-antifungal effect of the combination of anidulafungin with amphotericin B and fluconazole against fluconazolesusceptible and -resistant Candida albicans [PDF]
Current Medical Mycology, 2022 Background and Purpose: Invasive candidiasis is a life-threatening condition that kills a large number of immunocompromised patients each year worldwide.
narges aslani +7 more
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Multidrug-resistant Candida glabrata strains obtained by induction of anidulafungin resistance in planktonic and biofilm cells [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2019 Candida glabrata has emerged as a common cause of serious life-threatening fungal infections, largely owing to their low susceptibility to azole antifungals. Recent guidance indicates the use of echinocandins as the first-choice drug for the treatment of
Camila Hatwig +5 more
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Anidulafungin-Induced Suicidal Erythrocyte Death [PDF]
Cellular Physiology and Biochemistry, 2016 Background/Aims: The novel antifungal drug Anidulafungin is used for the treatment of diverse fungal infections including candidiasis and aspergillosis.
Thomas Peter +3 more
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Discovery of Small-Molecule PD-L1 Inhibitors via Virtual Screening and Their Immune-Mediated Anti-Tumor Effects [PDF]
PharmaceuticalsBackground/Objectives: Monoclonal antibodies targeting the PD-1/PD-L1 immune checkpoint have achieved clinical success but face drawbacks such as poor oral bioavailability, limited tumor penetration, and immune-related adverse events.
Chunlai Feng +6 more
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Caspofungin versus anidulafungin in patients with invasive candidiasis: a retrospective study with propensity-score-matched analysis [PDF]
Therapeutic Advances in Infectious DiseaseBackground: Echinocandins are recommended as an initial treatment for invasive candidiasis. Although safety and efficacy profiles of both anidulafungin and caspofungin are well established, direct head-to-head comparisons have not been reported before ...
Reem Hasan Elajez +10 more
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Fast detection of synergy and antagonism in antifungal combinations used against Candida albicans clinical isolates [PDF]
Scientific ReportsThe rise in antifungal resistance has limited treatment options for serious fungal infections, emphasizing the need for effective combination therapies. However, low-cost and rapid systems to evaluate synergy and antagonism in antifungal combinations are
Hanna Lundvik +5 more
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Reviews Of Anti‐infective Agents: Anidulafungin: A Novel Echinocandin [PDF]
Clinical Infectious Diseases, 2006 Jack D Sobel
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