Results 11 to 20 of about 11,372 (280)

Efficacy of liposomal amphotericin B and anidulafungin using an antifungal lock technique (ALT) for catheter-related Candida albicans and Candida glabrata infections in an experimental model. [PDF]

open access: yesPLoS ONE, 2019
ObjectiveThe aims of this study were as follows. First, we sought to compare the in vitro susceptibility of liposomal amphotericin B (LAmB) and anidulafungin on Candida albicans and Candida glabrata biofilms growing on silicone discs.
Jana Basas   +4 more
doaj   +7 more sources

Anidulafungin-Induced Suicidal Erythrocyte Death [PDF]

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: The novel antifungal drug Anidulafungin is used for the treatment of diverse fungal infections including candidiasis and aspergillosis.
Thomas Peter   +3 more
doaj   +3 more sources

Human Tissue Distribution of Anidulafungin and Micafungin

open access: yesAntimicrobial Agents and Chemotherapy, 2021
Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin.
J. Marx   +5 more
semanticscholar   +4 more sources

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species

open access: yesJournal of Fungi, 2020
Rezafungin is a next-generation echinocandin that has favorable pharmacokinetic properties. We compared the occurrence of paradoxical growth (PG) and trailing effect (TE) characteristics to echinocadins with rezafungin, caspofungin, micafungin and ...
Zoltán Tóth   +9 more
doaj   +2 more sources

Comparison of antifungal drugs in the treatment of invasive pulmonary aspergillosis: a systematic review and network meta-analysis [PDF]

open access: yesFrontiers in Microbiology
BackgroundVoriconazole, isavuconazole, and amphotericin (AmB) formulations are currently recommended to treat invasive pulmonary aspergillosis (IPA).
Jing Cheng   +5 more
doaj   +2 more sources

Anidulafungin and its role in candida infections

open access: yesInfection and Drug Resistance, 2009
Diane M Cappelletty, Rose JungThe University of Toledo, College of Pharmacy, Toledo, OH, USAAbstract: Candida infections continue to play a significant role not only in critically ill and immunocompromised patients but also in non-compromised patients ...
Diane M Cappelletty, Rose Jung
doaj   +5 more sources

Pharmacokinetics of Anidulafungin in Obese and Normal-Weight Adults [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2018
In 2025, approximately one out of five adults will be obese. Physiological changes associated with obesity have been shown to influence the pharmacokinetics of drugs.
R. Wasmann   +6 more
semanticscholar   +6 more sources

Safety of anidulafungin in solid organ transplant recipients [PDF]

open access: bronzeLiver Transplantation, 2012
The aim of this study was the evaluation of the safety of anidulafungin in adult solid organ transplantation (SOT) recipients. During the study period (14 months), we included all consecutive SOT recipients from 14 centers who received anidulafungin for at least 48 hours for the treatment of invasive fungal infections (IFIs ...
José María Aguado   +10 more
openalex   +6 more sources

Optimizing anidulafungin exposure across a wide adult body size range

open access: yesAntimicrobial Agents and Chemotherapy, 2023
Echinocandins like anidulafungin are first-line therapies for candidemia and invasive candidiasis, but their dosing may be suboptimal in obese patients.
Ronald G. Hall   +5 more
semanticscholar   +1 more source

Heightened efficacy of anidulafungin when used in combination with manogepix or 5-flucytosine against Candida auris in vitro

open access: yesbioRxiv, 2022
Candida auris is an emerging, multidrug-resistant fungal pathogen that causes refractory colonization and life-threatening, invasive nosocomial infections. The high proportion of C.
L. L. John   +6 more
semanticscholar   +1 more source

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