Results 41 to 50 of about 12,047 (282)

Anidulafungin Versus Micafungin in the Treatment of Candidemia in Adult Patients [PDF]

Mycopathologia, 2020
Echinocandins are recommended for the treatment of invasive candidiasis and candidemia. However, there are few studies comparing anidulafungin and micafungin in terms of efficacy and safety.
Jin Woong Suh, Sun Bean Kim, Young Kyung Yoon, Jang Wook Sohn, Min Ja Kim, Jong Hun Kim   +5 more
openalex   +2 more sources

Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy

Journal of Fungi, 2022
The isolation of a pan-echinocandin-resistant Candida parapsilosis strain (anidulafungin, caspofungin, micafungin and rezafungin EUCAST MICs > 8 mg/L) from urine of a patient following prolonged exposure to echinocandins (38 days of micafungin followed ...
Maria Siopi, Antonios Papadopoulos, Anastasia Spiliopoulou, Fotini Paliogianni, Nissrine Abou-Chakra, Maiken Cavling Arendrup, Christina Damoulari, Georgios Tsioulos, Efthymia Giannitsioti, Frantzeska Frantzeskaki, Iraklis Tsangaris, Spyros Pournaras, Joseph Meletiadis   +12 more
doaj   +1 more source

Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies [PDF]

, 2015
Date of Acceptance: 23/07/2015 We thank Gillian Milne for help with electron microscopy, Sophie M. Schäfer for pilot experiments, and Emilia Mellado for strains. All authors acknowledge financial support of Gilead Sciences through Ph.D.
Gow, Neil A R, Lee, Keunsook, Munro, Carol A, Walker, Louise A   +3 more
core   +1 more source

Retrospective cohort study comparing the risk of severe hepatotoxicity in hospitalized patients treated with echinocandins for invasive candidiasis in the presence of confounding by indication

BMC Infectious Diseases, 2018
Background To compare the risk of severe hepatotoxicity with anidulafungin versus caspofungin and micafungin in hospitalized adults. Methods This retrospective cohort study combined data from two large US- based hospital electronic medical record ...
Francis Vekeman, Lisa Weiss, Jalal Aram, Raluca Ionescu-Ittu, Shahrzad Moosavi, Yongling Xiao, Wendy Y. Cheng, Rachel H. Bhak, Margaret Tawadrous, M. Rita Capparella, Philippe Montravers, Mei Sheng Duh   +11 more
doaj   +1 more source

Candidemia in cancer patients: phenotypical and molecular-genetic characteristics of antifungal drug resistance, pathogenic factor genes of Candida spp.

Сибирский онкологический журнал, 2022
Relevance. The global trend of rapid increase in resistance to antifungal drugs due to multiple factors, dictates the need for continuous monitoring of taxonomic structure and susceptibility of nosocomial pathogens, causing invasive fungal infections ...
N. S. Bagirova, E. A. Goremykina, P. V. Slukin, O. E. Khokhlova, N. K. Fursova, I. N. Petukhova, Z. V. Grigorievskaya   +6 more
doaj   +1 more source

Invasive pulmonary aspergillosis post extracorporeal membrane oxygenation support and literature review [PDF]

, 2014
The use of extracorporeal membrane oxygenation (ECMO) for reversible pulmonary failure in critically ill patients has increased over the last few decades.
Al-Shair, Armstrong-James, Aubron, Aubron, Bizzarro, Blot, Burket, Caillot, De Pauw, Elefanti, Estrada, Garcia, Hsu, Marasco, O’Neill, Patterson, Seyedmousavi, Upton, Walsh   +18 more
core   +3 more sources

Evaluation of Inoculum Preparation for Etest and EUCAST Broth Dilution to Detect Anidulafungin Polyresistance in Candida glabrata

Antimicrobial Agents and Chemotherapy, 2022
The influence of inoculum preparation in EUCAST broth dilution and Etest to detect the coexistence of resistant and susceptible Candida subpopulations (defined as polyresistance [PR]) was evaluated.
M. Knoll, E. Samardzic, W. Posch, C. Lass‐Flörl   +3 more
semanticscholar   +1 more source

Parallel and cross-resistances of clinical yeast isolates determined by susceptibility pattern analysis

GMS Infectious Diseases, 2016
For calculated initial antifungal therapy, knowledge on parallel and cross-resistances are vitally important particularly in the case of multiresistant isolates.
Schmalreck, Arno F., Willinger, Birgit, Idelevich, Evgeny A., Fegeler, Christian, Lass-Flörl, Cornelia, Fegeler, Wolfgang, Becker, Karsten   +6 more
doaj   +1 more source

In vitro synergy of echinocandins with triazoles against fluconazole-resistant Candida parapsilosis complex isolates

Journal of Global Antimicrobial Resistance, 2020
Introduction: Candida parapsilosis (C. parapsilosis) is a common non-albicans Candida species ranked as the second common cause of bloodstream infections. Azole resistance and elevated echinocandin MICs have been reported for these fungi.
Ali Ahmadi, Shahram Mahmoudi, Sassan Rezaie, Sayed Jamal Hashemi, Eric Dannaoui, Hamid Badali, Mansoureh Ghaffari, Farzad Aala, Alireza Izadi, Aida Maleki, Jacques F. Meis, Sadegh Khodavaisy   +11 more
doaj   +1 more source

Invasive candidiasis in children

Журнал инфектологии, 2021
The prevalence of invasive candidiasis (IC) in pediatric hospitals is from 4,3 to 15,2 per 10,000 hospitalized, in ICU – from 3,5 to 7 cases per 1,000, with HSCT – 2,9%. The average length of stay of a patient in the hospital before the development of IC
N. N. Klimko, O. P. Kozlova
doaj   +1 more source