Results 51 to 60 of about 10,059 (251)

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]

open access: yes, 2017
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E.   +6 more
core   +2 more sources

Anidulafungin induced reversible thrombocytopenia in a patient: A case report

open access: yesMedicine Science, 2018
Anidulafungin is a semisynthetic antifungal agent which is an echinocandin. Here, we presented elderly patient developed reversible severe thrombocytopenia due to anidulafungin.
Zubeyir Cebeci   +3 more
doaj   +1 more source

Comparing the results of invasive candidiasis prevention with anidulafungin vs. the lipid formulation of amphotericin B in high-risk patients in the early postoperative period after liver transplantation

open access: yesТрансплантология (Москва), 2020
Introduction. The development of invasive candidiasis leads to high mortality after liver transplantation. Choosing an effective prophylaxis is an important task.The study purpose was to compare the results  of invasive candidiasis prevention with ...
S. V. Zhuravel   +6 more
doaj   +1 more source

Anti-Fungal Drug Anidulafungin Inhibits SARS-CoV-2 Spike-Induced Syncytia Formation by Targeting ACE2-Spike Protein Interaction

open access: yesFrontiers in Genetics, 2022
Drug repositioning continues to be the most effective, practicable possibility to treat COVID-19 patients. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters target cells by binding to the ACE2 receptor via its spike (S ...
Shahzaib Ahamad   +7 more
doaj   +1 more source

Bench-to-bedside review: Candida infections in the intensive care unit. [PDF]

open access: yes, 2008
Invasive mycoses are life-threatening opportunistic infections and have emerged as a major cause of morbidity and mortality in critically ill patients.
Calandra, T., Marchetti, O., Méan, M.
core   +3 more sources

Anidulafungin

open access: bronzeInfectious Diseases in Clinical Practice, 2005
Anidulafungin (LY-303366, VER002) is a semisynthetic derivative of echinocandin B and a potent antifungal agent active against a wide spectrum of fungal pathogens. We reviewed published papers, abstracts, and data to provide an overview focusing on the microbiology of anidulafungin and its promise for treating fungal infections. Anidulafungin was found
Mahmoud Ghannoum, Maurissa D'Angelo
openalex   +3 more sources

Human Tissue Distribution of Anidulafungin and Micafungin

open access: yesAntimicrobial Agents and Chemotherapy, 2021
Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin. The largest amounts were recovered from liver, with anidulafungin concentrations of 11.01 to 66.50 μg/g and micafungin levels of ...
Jana Marx   +5 more
openaire   +3 more sources

Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]

open access: yes, 2014
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar   +6 more
core   +2 more sources

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum

open access: yesMicroorganisms, 2021
Candida auris is an emerging and frequently multidrug-resistant pathogen against which the echinocandins are the preferred therapeutic option. We compared killing activities of anidulafungin, caspofungin, micafungin, and rezafungin against 13 isolates ...
Renátó Kovács   +7 more
doaj   +1 more source

Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]

open access: yes, 2019
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire   +2 more
core   +2 more sources

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