Results 51 to 60 of about 10,059 (251)
Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E. +6 more
core +2 more sources
Anidulafungin induced reversible thrombocytopenia in a patient: A case report
Anidulafungin is a semisynthetic antifungal agent which is an echinocandin. Here, we presented elderly patient developed reversible severe thrombocytopenia due to anidulafungin.
Zubeyir Cebeci +3 more
doaj +1 more source
Introduction. The development of invasive candidiasis leads to high mortality after liver transplantation. Choosing an effective prophylaxis is an important task.The study purpose was to compare the results of invasive candidiasis prevention with ...
S. V. Zhuravel +6 more
doaj +1 more source
Drug repositioning continues to be the most effective, practicable possibility to treat COVID-19 patients. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters target cells by binding to the ACE2 receptor via its spike (S ...
Shahzaib Ahamad +7 more
doaj +1 more source
Bench-to-bedside review: Candida infections in the intensive care unit. [PDF]
Invasive mycoses are life-threatening opportunistic infections and have emerged as a major cause of morbidity and mortality in critically ill patients.
Calandra, T., Marchetti, O., Méan, M.
core +3 more sources
Anidulafungin (LY-303366, VER002) is a semisynthetic derivative of echinocandin B and a potent antifungal agent active against a wide spectrum of fungal pathogens. We reviewed published papers, abstracts, and data to provide an overview focusing on the microbiology of anidulafungin and its promise for treating fungal infections. Anidulafungin was found
Mahmoud Ghannoum, Maurissa D'Angelo
openalex +3 more sources
Human Tissue Distribution of Anidulafungin and Micafungin
Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin. The largest amounts were recovered from liver, with anidulafungin concentrations of 11.01 to 66.50 μg/g and micafungin levels of ...
Jana Marx +5 more
openaire +3 more sources
Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar +6 more
core +2 more sources
Candida auris is an emerging and frequently multidrug-resistant pathogen against which the echinocandins are the preferred therapeutic option. We compared killing activities of anidulafungin, caspofungin, micafungin, and rezafungin against 13 isolates ...
Renátó Kovács +7 more
doaj +1 more source
Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire +2 more
core +2 more sources

