Results 61 to 70 of about 12,047 (282)

SRSF5‐Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host‐Directed Target Against Influenza Virus

Advanced Science, 2022
Splicing of influenza A virus (IAV) RNA is an essential process in the viral life cycle that involves the co‐opting of host factors. Here, it is demonstrated that induction of host serine and arginine‐rich splicing factor 5 (SRSF5) by IAV facilitated ...
Qiuchen Li, Zhimin Jiang, Shuning Ren, Hui Guo, Zhimin Song, Saini Chen, Xintao Gao, Fanfeng Meng, Junda Zhu, Litao Liu, Qi Tong, Honglei Sun, Yipeng Sun, Juan Pu, Kin‐Chow Chang, Jinhua Liu   +15 more
doaj   +1 more source

Two cases of fungal keratitis caused by Metarhizium anisopliae [PDF]

, 2018
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates
Burd, Eileen M, Burnham, Carey-Ann D, Goodman, Abigail L, Lockhart, Shawn R, Lysen, Colleen B, Westblade, Lars F   +5 more
core   +2 more sources

Human Tissue Distribution of Anidulafungin and Micafungin

Antimicrobial Agents and Chemotherapy, 2021
Concentrations of anidulafungin and micafungin were determined in eight different tissues obtained during autopsy of four deceased individuals who had been treated with anidulafungin and of seven who had received micafungin.
J. Marx, René Welte, Tiziana Gasperetti, P. Moser, M. Joannidis, R. Bellmann   +5 more
semanticscholar   +1 more source

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]

, 2017
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E., Mello, E., Perlin, D.S., Posteraro, B., Sanglard, D., Sanguinetti, M., Vella, A.   +6 more
core   +2 more sources

Anidulafungin induced reversible thrombocytopenia in a patient: A case report

Medicine Science, 2018
Anidulafungin is a semisynthetic antifungal agent which is an echinocandin. Here, we presented elderly patient developed reversible severe thrombocytopenia due to anidulafungin.
Zubeyir Cebeci, Ayse Ilksen Egilmez, Yasin Tire, Mehmet Sargin   +3 more
doaj   +1 more source

Safety, Efficacy and Pharmacokinetics of Anidulafungin in Patients 1 Month to <2 Years of Age With Invasive Candidiasis, Including Candidemia

The Pediatric Infectious Disease Journal, 2020
Nineteen patients 1 month to
E. Roilides, F. Carlesse, M. Tawadrous, H. Leister-Tebbe, U. Conte, S. Raber, R. Swanson, J. Yan, J. Aram, F. Queiroz-Telles   +9 more
semanticscholar   +1 more source

Micafungin versus anidulafungin in critically ill patients with invasive candidiasis: A retrospective study [PDF]

, 2016
_Background:_ In critically ill patients the incidence of invasive fungal infections caused by Candida spp. has increased remarkably. Echinocandins are recommended as initial treatment for invasive fungal infections. The safety and efficacy of micafungin
Geest, P.J. (Patrick) van der, Groeneveld, A.B.J. (Johan), Hunfeld, N.G.M. (Nicole), Ladage, S.E. (Sophie E.)   +3 more
core   +5 more sources

Echinocandins Pharmacokinetics: A Comprehensive Review of Micafungin, Caspofungin, Anidulafungin, and Rezafungin Population Pharmacokinetic Models and Dose Optimization in Special Populations

Clinical Pharmacokinetics
In recent years, many population pharmacokinetic (popPK) models have been developed for echinocandins to better understand the pharmacokinetics (PK) of these antifungals.
Marta Albanell-Fernández
semanticscholar   +1 more source

Phenomenon of Dip Effect in Antifungal Susceptibility Testing of Candida tropicalis by using MIC Testing Strips against Echinocandins [PDF]

Journal of Clinical and Diagnostic Research
Minimum Inhibitory Concentration (MIC) of an antifungal is the minimum concentration that completely inhibits the visible growth of fungi under regulated, uniform and consistent in-vitro conditions.
Sujata lall, Vivek Bhat
doaj   +1 more source

Comparing the results of invasive candidiasis prevention with anidulafungin vs. the lipid formulation of amphotericin B in high-risk patients in the early postoperative period after liver transplantation

Трансплантология (Москва), 2020
Introduction. The development of invasive candidiasis leads to high mortality after liver transplantation. Choosing an effective prophylaxis is an important task.The study purpose was to compare the results  of invasive candidiasis prevention with ...
S. V. Zhuravel, N. K. Kuznetsova, I. I. Utkina, M. S. Novruzbekov, P. V. Gavrilov, T. V. Chernenkaya, G. K. Ospanova   +6 more
doaj   +1 more source