Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation
Urology Case Reports, 2021 A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C.
N.A.M. van Merode +3 more
doaj +1 more source
Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study [PDF]
, 2015 Background: Invasive candidiasis (IC) is a frequent and life-threatening infection in critically ill patients. The aim of this study was to evaluate the epidemiology of IC and the antifungal susceptibility of etiological agents in patients admitted to ...
Ana Izquierdo +34 more
core +1 more source
Micafungin versus anidulafungin in critically ill patients with invasive candidiasis: A retrospective study [PDF]
, 2016 _Background:_ In critically ill patients the incidence of invasive fungal infections caused by Candida spp. has increased remarkably. Echinocandins are recommended as initial treatment for invasive fungal infections. The safety and efficacy of micafungin
Geest, P.J. (Patrick) van der +3 more
core +5 more sources
Pharmacokinetics and Tissue Distribution of Anidulafungin in Rats [PDF]
Antimicrobial Agents and Chemotherapy, 2008 ABSTRACT This study assessed the tissue distribution of anidulafungin in rats. Anidulafungin rapidly distributed into tissues, achieving peak concentrations within 30 min, and maintained levels above MICs for common pathogens over 72 h. In tissues susceptible to fungal infection (liver, lung, spleen, kidney), exposure was 9- to 12-fold higher
Martin Stogniew +2 more
openaire +3 more sources
Journal of Fungi, 2019 This paper reviews recent advances in three selected areas of pediatric invasive candidiasis: epidemiology, diagnosis, and treatment. Although the epidemiological trends of pediatric invasive candidiasis illustrate a declining incidence, this infection ...
Thomas J. Walsh +4 more
doaj +1 more source
Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity
Pharmaceuticals, 2021 Fission yeast contains three essential β(1,3)-D-glucan synthases (GSs), Bgs1, Bgs3, and Bgs4, with non-overlapping roles in cell integrity and morphogenesis.
Natalia Yagüe +7 more
doaj +1 more source
Fungal infections of the central nervous system: A review of fungal pathogens and treatment [PDF]
, 2007 Multiple factors influence the outcome of fungal infection of the central nervous system (CNS). The host and the pathogen in concert with drug delivery across the blood-brain barrier and drug activity are key factors in outcome.
Dancer, C., Redmond, A., Woods, M. L.
core +1 more source
Chemistry &Biodiversity, EarlyView.ABSTRACT Plinia cauliflora (DC.) Kausel (jabuticaba) is traditionally used by Brazilian indigenous communities for therapeutic purposes, including the treatment of wounds and inflammation. This study investigated the phytochemical composition and biological activities of an ethanolic extract derived from P.
Priscila de Lima Paula +17 more
wiley +1 more source
Time-Kill Kinetics and In Vitro Antifungal Susceptibility of Non-fumigatus Aspergillus Species Isolated from Patients with Ocular Mycoses [PDF]
, 2015 Aspergillus species can cause ocular morbidity and blindness, and thus, appropriate antifungal therapy is needed. We investigated the in vitro activity of itraconazole, voriconazole, posaconazole, caspofungin, anidulafungin, and amphotericin B against 14
Gökbolat, E. (Egemen) +5 more
core +8 more sources
Activity of anidulafungin in a murine model of Candida krusei infection: evaluation of mortality and disease burden by quantitative tissue cultures and measurement of serum (1,3)-beta-D-glucan levels. [PDF]
, 2009 Experience with anidulafungin against Candida krusei is limited. Immunosuppressed mice were injected with 1.3 x 10(7) to 1.5 x 10(7) CFU of C. krusei.
Chen, Enuo +4 more
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