Results 71 to 80 of about 11,372 (280)

Safety, Efficacy and Pharmacokinetics of Anidulafungin in Patients 1 Month to <2 Years of Age With Invasive Candidiasis, Including Candidemia

The Pediatric Infectious Disease Journal, 2020
Nineteen patients 1 month to
E. Roilides, F. Carlesse, M. Tawadrous, H. Leister-Tebbe, U. Conte, S. Raber, R. Swanson, J. Yan, J. Aram, F. Queiroz-Telles   +9 more
semanticscholar   +1 more source

Comparing the results of invasive candidiasis prevention with anidulafungin vs. the lipid formulation of amphotericin B in high-risk patients in the early postoperative period after liver transplantation

Трансплантология (Москва), 2020
Introduction. The development of invasive candidiasis leads to high mortality after liver transplantation. Choosing an effective prophylaxis is an important task.The study purpose was to compare the results  of invasive candidiasis prevention with ...
S. V. Zhuravel, N. K. Kuznetsova, I. I. Utkina, M. S. Novruzbekov, P. V. Gavrilov, T. V. Chernenkaya, G. K. Ospanova   +6 more
doaj   +1 more source

Successful Treatment of Bladder Fungus Ball Due to <i>Candida auris</i> With Systemic/Local Amphotericin B and Surgical Excision. [PDF]

Case Rep Pediatr
Fungal infections in the urine are rare in healthy individuals but can occur in patients with diabetes, immunosuppression, urinary catheterization, prolonged hospital stays, and the use of broad‐spectrum antibiotics. The most common strain is Candida, with Candida albicans being the most prevalent.
Erkol Yilmaz Y, Havan M, Eyduran E, Penezoğlu N, Öcal D, Teber S, Çiftçi E, Soygür YT, Kendirli T.   +8 more
europepmc   +2 more sources

Variability in antifungal and antiviral use in hospitalized children [PDF]

, 2017
We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S, Goldman, Jennifer L, Hersh, Adam L, Kronman, Matthew P, Lee, Brian R, Newland, Jason G, Ross, Rachael K   +6 more
core   +2 more sources

FKS1 mutation associated with decreased echinocandin susceptibility of Aspergillus fumigatus following anidulafungin exposure

Scientific Reports, 2020
Invasive aspergillosis (IA) is a potentially lethal infection that affects mostly immunocompromised patients caused by Aspergillus fumigatus. Echinocandins are a second-line therapy against IA, used as a salvage therapy as well as for empirical or ...
Ana Pinto e Silva, I. Miranda, Joana Branco, P. Oliveira, I. Faria-Ramos, Raquel M. Silva, A. Rodrigues, S. Costa-de-Oliveira   +7 more
semanticscholar   +1 more source

Anidulafungin

Infectious Diseases in Clinical Practice, 2005
Anidulafungin (LY-303366, VER002) is a semisynthetic derivative of echinocandin B and a potent antifungal agent active against a wide spectrum of fungal pathogens. We reviewed published papers, abstracts, and data to provide an overview focusing on the microbiology of anidulafungin and its promise for treating fungal infections. Anidulafungin was found
Mahmoud Ghannoum, Maurissa D'Angelo
openalex   +3 more sources

Time-Kill Kinetics and In Vitro Antifungal Susceptibility of Non-fumigatus Aspergillus Species Isolated from Patients with Ocular Mycoses [PDF]

, 2015
Aspergillus species can cause ocular morbidity and blindness, and thus, appropriate antifungal therapy is needed. We investigated the in vitro activity of itraconazole, voriconazole, posaconazole, caspofungin, anidulafungin, and amphotericin B against 14
Gökbolat, E. (Egemen), Ilkit, M., Kiraz, N. (Nuri), Ozdemir, H.G. (Havva Gül), Seyedmousavi, S. (Seyedmojtaba), Öz, Y. (Yasemin)   +5 more
core   +4 more sources

Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

Pharmaceuticals, 2021
Fission yeast contains three essential β(1,3)-D-glucan synthases (GSs), Bgs1, Bgs3, and Bgs4, with non-overlapping roles in cell integrity and morphogenesis.
Natalia Yagüe, Laura Gómez-Delgado, M. Ángeles Curto, Vanessa S. D. Carvalho, M. Belén Moreno, Pilar Pérez, Juan Carlos Ribas, Juan Carlos G. Cortés   +7 more
doaj   +1 more source

Invasive Candidiasis in Infants and Children: Recent Advances in Epidemiology, Diagnosis, and Treatment

Journal of Fungi, 2019
This paper reviews recent advances in three selected areas of pediatric invasive candidiasis: epidemiology, diagnosis, and treatment. Although the epidemiological trends of pediatric invasive candidiasis illustrate a declining incidence, this infection ...
Thomas J. Walsh, Aspasia Katragkou, Tempe Chen, Christine M. Salvatore, Emmanuel Roilides   +4 more
doaj   +1 more source

Population pharmacokinetics of anidulafungin in ICU patients assessing inter‐ and intrasubject variability

British Journal of Clinical Pharmacology, 2020
The population pharmacokinetics (PK) of anidulafungin in critically ill patients hospitalized in intensive care units (ICUs) was explored with the intention of evaluating and optimizing dosing regimens.
I. Kapralos, E. Mainas, O. Apostolopoulou, M. Siopi, E. Neroutsos, Stella Apostolidi, G. Dimopoulos, H. Sambatakou, G. Valsami, J. Meletiadis, A. Dokoumetzidis   +10 more
semanticscholar   +1 more source