Results 71 to 80 of about 12,047 (282)

Fungal infections of the central nervous system: A review of fungal pathogens and treatment [PDF]

, 2007
Multiple factors influence the outcome of fungal infection of the central nervous system (CNS). The host and the pathogen in concert with drug delivery across the blood-brain barrier and drug activity are key factors in outcome.
Dancer, C., Redmond, A., Woods, M. L.
core   +1 more source

In Vivo Efficacy of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in a Neutropenic Mouse Bloodstream Infection Model

Journal of Fungi
Objectives: Rezafungin is the first new drug approved to treat candidaemia and invasive candidiasis in more than 10 years. However, data are scant on the in vivo efficacy of rezafungin and the other three approved echinocandins against different Candida ...
Dávid Balázsi, Zoltán Tóth, J. B. Locke, A. Borman, Lajos Forgács, Noémi Balla, F. Kovács, R. Kovács, Chiaki Amano, Tugba Ilay Baran, L. Majoros   +10 more
semanticscholar   +1 more source

Epidemiology of invasive candidiasis in a surgical intensive care unit: an observational study [PDF]

, 2015
Background: Invasive candidiasis (IC) is a frequent and life-threatening infection in critically ill patients. The aim of this study was to evaluate the epidemiology of IC and the antifungal susceptibility of etiological agents in patients admitted to ...
Ana Izquierdo, C León, Carlos Delgado, Carlos Ferrando, CM Chalmers, David Navarro, DR Andes, E Bouza, Estefanía Gracia, Esther Romero, F Tissot, F. Javier Belda, G Dimopoulos, Gerardo Aguilar, H Dupont, Isabel Corrales, JK Chow, JL Vincent, José A. Carbonell, KW Garey, M Kollef, M Nucci, M Pratikaki, M Puig-Asensio, ME Bougnoux, MT Montagna, O Leroy, OA Cornely, P Montravers, P Montravers, P Sandven, PG Pappas, R Jordá-Marcos, Rafael Borrás, Tania Moreno   +34 more
core   +1 more source

Bench-to-bedside review: Candida infections in the intensive care unit. [PDF]

, 2008
Invasive mycoses are life-threatening opportunistic infections and have emerged as a major cause of morbidity and mortality in critically ill patients.
Calandra, T., Marchetti, O., Méan, M.
core   +3 more sources

Criteria for the administration of systemic antimicotic therapy in surgical intensive care units (literature review)

Тазовая хирургия и онкология, 2019
This review focuses on the practical aspects of prevention and treatment of fungal infections in surgical patients. It covers epidemiology and risk factors for invasive candidiasis, updates on the etiological structure of fungal infections in patients in
B. Z. Belotserkovskiy, E. B. Gelfand, A. O. Bykov, O. A. Mamontova, D. N. Protsenko   +4 more
doaj   +1 more source

Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation

Urology Case Reports, 2021
A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C.
N.A.M. van Merode, J.J. Pat, M.J.H.M. Wolfhagen, G.A. Dijkstra   +3 more
doaj   +1 more source

Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]

, 2014
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar, Breda, Giovanni Luis, Colombo, Arnaldo L., Jimenez-Ortigosa, Cristina, Perlin, David S., Queiroz-Telles, Flavio, Souza, Ana Carolina R.   +6 more
core   +2 more sources

Repurposing Anidulafungin for Alzheimer’s Disease via Fragment-Based Drug Discovery

ACS Chemical Neuroscience
The misfolding and aggregation of beta-amyloid (Aβ) peptides have been implicated as key pathogenic events in the early stages of Alzheimer’s disease (AD).
Siqi Xie, Yumei Liang, Yang Song, Tingting Li, J. Jia   +4 more
semanticscholar   +1 more source

Echinocandin Drugs Induce Differential Effects in Cytokinesis Progression and Cell Integrity

Pharmaceuticals, 2021
Fission yeast contains three essential β(1,3)-D-glucan synthases (GSs), Bgs1, Bgs3, and Bgs4, with non-overlapping roles in cell integrity and morphogenesis.
Natalia Yagüe, Laura Gómez-Delgado, M. Ángeles Curto, Vanessa S. D. Carvalho, M. Belén Moreno, Pilar Pérez, Juan Carlos Ribas, Juan Carlos G. Cortés   +7 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources