Results 61 to 70 of about 281,616 (305)

Children's acquisition of science terms: does fast mapping work? [PDF]

open access: yes, 2001
About the book: This proceedings contains 99 selected papers from the 8th Conference of the International Association for the Study of Child Language (IASCL) held in Donostia-San Sebastián in the Spanish Basque Country in July 1999.
Best, Rachel M.   +2 more
core  

Tests of fit for the logarithmic distribution [PDF]

open access: yes, 2008
Smooth tests for the logarithmic distribution are compared with three tests: the first is a test due to Epps and is based on a probability generating function, the second is the Anderson-Darling test, and the third is due to Klar and is based on the ...
Best, DJ, Rayner, JCW, Thas, Olivier
core   +5 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Socio-economic impacts of alternative GIN control practices. Project deliverable 11 (WP4) [PDF]

open access: yes, 2018
This report is a deliverable (WP4) from the EU-funded PrOPara project. The PrOPara project aspires to i) assess existing knowledge from research, development and benchmarking studies on alternatives to parasite control on organic ruminant farms, ii ...
Moakes, Simon, Quiédeville, Sylvain
core  

One Health in food safety and security education: Subject matter outline for a curricular framework. [PDF]

open access: yes, 2017
Educating students in the range of subjects encompassing food safety and security as approached from a One Health perspective requires consideration of a variety of different disciplines and the interrelationships among disciplines. The Western Institute
Angelos, John A   +4 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Potential dietary feed additives with antibacterial effects and their impact on performance of weaned piglets : a meta-analysis [PDF]

open access: yes, 2019
This meta-analysis evaluated the use of potential dietary feed additives (pDFA) with antibacterial effects and their impact on the perfomance of weaned piglets.
Bruggeman, G   +8 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The (misleading) role of animal models in drug development

open access: yesFrontiers in Drug Discovery
Animals like mice and rats have long been used in medical research to help understand disease and test potential new treatments before human trials. However, while animal studies have contributed to important advances, too much reliance on animal models ...
Thomas Hartung, Thomas Hartung
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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