Results 41 to 50 of about 34,414 (193)
Ankyrin‐B is a critical determinant of vasomotor function
The FASEB Journal, 2010 Ankyrin B (AnkB) plays an important role in normal cardiac and neuronal function by linking membrane proteins to the cytoskeleton. Little is known, however, about the role of AnkB in the vasculature. Thus, we studied vasomotor function in aortas from wild‐type mice (AnkB
Shane R Cunha +2 more
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The Role of BANK1 in B Cell Signaling and Disease
Cells, 2021 The B cell scaffold protein with ankyrin repeats (BANK1) is expressed primarily in B cells and with multiple but discrete roles in B cell signaling, including B cell receptor signaling, CD40-related signaling, and Toll-like receptor (TLR) signaling.
Gonzalo Gómez Hernández +2 more
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Ankyrin-B Binds Disparate Proteins to Keep Calcium Flowing in the Heart
PLoS Biology, 2005 doaj +3 more sources
Virology Journal, 2011 Background The carboxyl terminal of Epstein-Barr virus (EBV) ZEBRA protein (also termed BZLF-1 encoded replication protein Zta or ZEBRA) binds to both NF-κB and p53. The authors have previously suggested that this interaction results from an ankyrin-like
Ghoda Lucy Y +3 more
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Alternative splicing: A key mechanism for ankyrin-B functional diversity? [PDF]
Journal of Molecular and Cellular Cardiology, 2008 Ankyrin is a family of adaptor proteins encoded by three genes, ANK1, ANK2 and ANK3 (also known as ankyrin-R, ankyrin-B and ankyrin-G, respectively) [1]. The ankyrins serve to link specific membrane proteins to the cellular cytoskeleton and help membrane proteins remain stably positioned in the correct location within the cell. The ankyrins contain 24 “
Ralph J. van Oort +3 more
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Current diagnostic approach and screening methods for hereditary spherocytosis
Thalassemia Reports, 2013 The plasma membrane of the erythrocyte accounts for all of its antigenic, transport, and mechanical characteristics, particularly its ability to undergo large passive deformations during repeated passage through the narrow capillaries of the ...
Paola Bianchi
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Ankyrin-B Reduction Enhances Calcium Sparks via CamkII [PDF]
Biophysical Journal, 2014 Ankyrin-B (AnkB) is a scaffolding protein that tethers to the cytoskeleton and targets select membrane proteins, including the Na+/Ca2+ exchanger and Na+/K+-ATPase, key regulators of cardiac contractility and arrhythmogenesis. Humans with loss-of-function mutations in AnkB and mice heterozygous for a null mutation in AnkB (AnkB+/- mice) display a ...
Galice, Samuel, Despa, Sanda
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BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling. [PDF]
PLoS ONE, 2013 The B cell adaptor protein with ankyrin repeats (BANK1) and the B lymphoid tyrosine kinase (BLK) have been genetically associated with autoimmunity. The proteins of these genes interact physically and work in concert during B-cell signaling.
Manuel Bernal-Quirós +3 more
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Developmental mechanism of the periodic membrane skeleton in axons
eLife, 2014 Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown.
Guisheng Zhong +6 more
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Ankyrin-B Is Required for Intracellular Sorting of Structurally Diverse Ca2+ Homeostasis Proteins [PDF]
The Journal of Cell Biology, 1999 This report describes a congenital myopathy and major loss of thymic lymphocytes in ankyrin-B (−/−) mice as well as dramatic alterations in intracellular localization of key components of the Ca2+ homeostasis machinery in ankyrin-B (−/−) striated muscle and thymus.
S, Tuvia +4 more
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