Results 31 to 40 of about 3,792 (162)
Journal of Animal Reproduction and Biotechnology, 2022 Receptor tyrosine kinase c-Kit, a marker found on interstitial cells of Cajal (ICCs), is expressed in Leydig cells, which are testicular interstitial cells. The expression of other ICC markers has not yet been reported. In this study, we investigated the
Eun-A Ko, Min Seok Woo, Dawon Kang
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Anoctamin 1 Contributes to Inflammatory and Nerve-Injury Induced Hypersensitivity
Molecular Pain, 2014 Background: Various pathological conditions such as inflammation or injury can evoke pain hypersensitivity. That represents the response to innocuous stimuli or exaggerated response to noxious stimuli.
Byeongjun Lee +5 more
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Communications Biology, 2023 Mechanical force loading is essential for maintaining bone homeostasis, and unloading exposure can lead to bone loss. Osteoclasts are the only bone resorbing cells and play a crucial role in bone remodeling. The molecular mechanisms underlying mechanical
Weijia Sun +21 more
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Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells [PDF]
PeerJ, 2023 Solithromycin is a novel fluoroketolide antibiotic belonging to the class of macrolide antibiotics. Activation of the interleukin (IL)-13 receptor leads to STAT6 activation and subsequent induction of SAM pointed domain containing ETS transcription ...
Yasuhiro Kimura +3 more
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PLoS ONE, 2015 The calcium-activated chloride channel Ano1 (TMEM16A) is overexpressed in many tumors. Although Ano1 overexpression is found in breast cancer due to 11q13 amplification, it remains unclear whether signaling pathways are involved in Ano1 overexpression ...
Huizhe Wu +11 more
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Molecular Pain, 2015 Background Anoctamin 1 (ANO1 or TMEM16A) Ca 2+ -gated Cl − channels of nociceptor neurons are emerging as important molecular components of peripheral pain transduction. At physiological intracellular Cl − concentrations ([Cl − ] i ) sensory neuronal Cl −
Farah Deba, Bret F. Bessac
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Identification of novel inhibitors of ANO1.
, 2016 A) Chemical structures of ANO1 inhibitors. B) Apical membrane current measured in ANO1 expressing FRT cells in the presence of a transepithelial chloride gradient.
Jinhong Park (161037) +6 more
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Cells, 2020 TMEM16A/anoctamin1 (ANO1), a calcium (Ca2+)-activated chloride (Cl−) channel, has many functions in various excitable cells and modulates excitability in both Ca2+- and voltage-gating modes.
Sun-Sook Paik +2 more
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Ano1 as a regulator of proliferation
, 2011 Ano1 is a recently discovered Ca2+-activated Cl− channel expressed on interstitial cells of Cajal (ICC) that has been implicated in slow-wave activity in the gut.
Tamas Ordog +7 more
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Understanding the Role of ANO1 in Oral Cancer
, 2021 In 2008, the gene ANO1 was discovered to encode a calcium activated chloride channel. This gene is located on the 11q13 locus, a locus that is commonly amplified in many cancers including cancer of the head and neck.
Forrest, Mallary
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