Results 41 to 50 of about 3,792 (162)
Cellular Physiology and Biochemistry, 2014 Background/Aims: Iodide efflux from thyroid cells into the follicular lumen is essential for the synthesis of thyroid hormones, however, the pathways mediating this transport have only been partially identified.
Carmela Iosco +10 more
doaj +1 more source
Ano1 supports regulatory volume decrease.
, 2012 A) Original recordings of the calcein fluorescence in BHY cells, treated with scrambled RNA or siRNA-Ano1, before and after stimulation with 100 µM ATP. ATP induces transient cell shrinkage that was not affected by siRNA-knockdown of Ano1.
Karl Kunzelmann (80303) +10 more
core +1 more source
Ano1 is a Prognostic Biomarker That is Correlated with Immune Infiltration in Colorectal Cancer
International Journal of General Medicine, 2022 Jun Chen,1,* Hongli Wang,2,* Fang Peng,3,* Haiyan Qiao,1 Linfeng Liu,1 Liang Wang,1 Bingbing Shang4 1Laboratory Animal Center, Dalian Medical University, Dalian, 116044, Liaoning Province, People’s Republic of China; 2Cardiology Department ...
Chen J +6 more
doaj
Andrology, EarlyView.ABSTRACT Background Spontaneous phasic contractions (SPCs) in the epididymal duct play an important role in transport and maturation of sperm. In proximal cauda of the rat epididymis, platelet‐derived growth factor receptor α (PDGFRα)‐positive smooth muscle cells (SMCs) generate ANO1 Ca2+‐activated chloride channels (CaCCs)‐dependent spontaneous ...
Wataru Kudo +5 more
wiley +1 more source
Inhibition of cell proliferation by ANO1 knockdown.
, 2015 (A) RNAi knockdown of ANO1 protein expression in ANO1 expressing cells was shown by Western blot images. The membrane proteins extracted from GLC82 and NCI-H520 cells on the 3rd day after transfection of different ANO1 shRNAs (shRNA1, shRNA2 and shRNA3 ...
Min Lu (238723) +4 more
core +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
, 2012 A) Summary of BrdU incorporation in BHY cells after various treatments, shown as % of BrdU incorporation, when compared to cells treated with scrambled RNA (red dashed line).
Karl Kunzelmann (80303) +10 more
core +1 more source
Anticancer effect of verteporfin on non-small cell lung cancer via downregulation of ANO1 [PDF]
, 2022 Anoctamin 1 (ANO1) is a calcium-activated chloride channel found in various cell types and is overexpressed in non-small cell lung cancer (NSCLC), a major cause of cancer-related mortality.
조병철
core +1 more source
PLoS ONE, 2015 Lung cancer or pulmonary carcinoma is primarily derived from epithelial cells that are thin and line on the alveolar surfaces of the lung for gas exchange. ANO1/TMEM16A, initially identified from airway epithelial cells, is a member of Ca2+-activated Cl-
Linghan Jia +4 more
doaj +1 more source