Anti-Carbamylated Protein Antibodies as a Reproducible Independent Type of Rheumatoid Arthritis Autoantibodies. [PDF]
PLoS ONE, 2016 A large fraction of the patients with rheumatoid arthritis (RA) develop specific autoantibodies, which until recently were only of two types, rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA).
Ariana Montes +5 more
doaj +11 more sources
Anti-carbamylated protein antibodies in systemic sclerosis [PDF]
Arthritis Research & Therapy, 2023 Background To investigate the presence of different isotypes of anti-carbamylated protein (CarP) antibodies in systemic sclerosis (SSc) patients and its association with skin involvement.
Sophie I. E. Liem +8 more
doaj +6 more sources
Increased disease activity in early arthritis patients with anti-carbamylated protein antibodies [PDF]
Scientific Reports, 2021 The initial management of rheumatoid arthritis (RA) has a high impact on disease prognosis. Therefore, we need to select the most appropriate treatment as soon as possible. This goal requires biomarkers of disease severity and prognosis.
Cristina Regueiro +10 more
doaj +7 more sources
Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus [PDF]
Arthritis Research & Therapy, 2018 Background The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Fulvia Ceccarelli +11 more
doaj +6 more sources
Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis [PDF]
Arthritis Research & Therapy, 2017 Background Rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) and anti-carbamylated protein (anti-CarP) antibodies are rheumatoid arthritis (RA)-associated autoantibodies. Besides their presence in human serum, anti-CarP antibodies have
Marije K. Verheul +4 more
doaj +7 more sources
Value of Measuring Anti-Carbamylated Protein Antibodies for Classification on Early Arthritis Patients [PDF]
Scientific Reports, 2017 Classification of patients with rheumatoid arthritis (RA) as quickly as possible improves their prognosis. This reason motivates specially dedicated early arthritis (EA) clinics.
Cristina Regueiro +9 more
doaj +7 more sources
Anti-carbamylated protein antibodies and skin involvement in patients with systemic sclerosis: An intriguing association. [PDF]
PLoS ONE, 2018 Carbamylation is a post-translational modification that mostly affects proteins with low turnover, such as dermal proteins. Carbamylated proteins accumulate in skin in an age-dependent manner, contributing to tissue alterations.
Elvira Favoino +6 more
doaj +7 more sources
The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients [PDF]
Arthritis Research & Therapy, 2017 Background Anti-carbamylated protein (anti-CarP) antibodies have recently been reported to occur in around 45% of rheumatoid arthritis (RA) patients and to have prognostic and diagnostic properties.
Myrthe A. M. van Delft +8 more
doaj +7 more sources
Serum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis [PDF]
BMC Musculoskeletal Disorders, 2022 Objective Rheumatoid arthritis (RA) is often complicated with chronic lung diseases (CLD), including interstitial lung disease (ILD) and airway disease, which occur as extra-articular manifestations.
Shomi Oka +13 more
doaj +3 more sources
Association of high titers of anti-carbamylated protein antibodies with decreased bone mineral density in early arthritis patients. [PDF]
PLoS ONE, 2018 Rheumatoid arthritis (RA) has a negative impact on bone that is partly mediated by anti-citrullinated proteins antibodies (ACPA). These antibodies are associated with erosions, and with juxta-articular and systemic bone loss. Other RA autoantibodies, the
Cristina Regueiro +5 more
doaj +3 more sources