Results 21 to 30 of about 131,343 (218)

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage. [PDF]

Arthritis Res Ther, 2015
IntroductionThe presence of a new autoantibody system, anti-carbamylated protein (anti-CarP) antibodies, has been identified in rheumatoid arthritis (RA).
Brink M, Verheul MK, Rönnelid J, Berglin E, Holmdahl R, Toes RE, Klareskog L, Trouw LA, Rantapää-Dahlqvist S.   +8 more
europepmc   +2 more sources

Effect of Etanercept on anti-carbamylated protein antibodies in patients with rheumatoid arthritis [PDF]

Journal of Rheumatic Diseases and Treatment, 2015
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e.
Alessandri, Cristiano, Ceccarelli, Fulvia, Conti, Fabrizio, Pecani, Arbi, Spinelli, FRANCESCA ROMANA   +4 more
core   +3 more sources

Role of Anti-Carbamylated Protein Antibodies Compared to Anti-Citrullinated Protein Antibodies in Indigenous North Americans With Rheumatoid Arthritis, Their First-Degree Relatives, and Healthy Controls. [PDF]

Arthritis Rheumatol, 2016
Rheumatoid arthritis (RA) is characterized by the presence of autoantibodies, including seropositivity for rheumatoid factor (RF) and anti–citrullinated protein antibodies (ACPAs).
Koppejan H, Trouw LA, Sokolove J, Lahey LJ, Huizinga TJ, Smolik IA, Robinson DB, El-Gabalawy HS, Toes RE, Hitchon CA.   +9 more
europepmc   +2 more sources

Do anti-carbamylated protein antibodies in rheumatoid arthritis reflect local and systemic osteoporosis? A study of osteoprotegrin and receptor activator for nuclear factor kappa B ligand and radiological assessment

Egyptian Rheumatology and Rehabilitation, 2021
Background One of the most important and dangerous complications of rheumatoid arthritis (RA) is bone loss, which manifested by erosions and juxta-articular or systemic bone loss.
Manal Shawky Hussein, Rasha Ahmed Gaber, Hala Mostafa Elsabagh, Elsayed Mohamed Rageh   +3 more
doaj   +2 more sources

Carbamylation/citrullination of IgG Fc in bronchiectasis, established RA with bronchiectasis and RA smokers: a potential risk factor for disease [PDF]

ERJ Open Research, 2017
Bronchiectasis (BR) and smoking are risk factors for rheumatoid arthritis (RA) development. The mechanisms by which smoking and BR trigger RA are unknown, but are associated with concurrent rheumatoid factor (RF) and anti-cyclic citrullinated peptide ...
David Hutchinson, Alexander Clarke, Kate Heesom, Daniel Murphy, Paul Eggleton   +4 more
doaj   +6 more sources

Protein carbamylation and proteomics: from artifacts to elucidation of biological functions [PDF]

Frontiers in Analytical Science
Lysine carbamylation is a non-enzymatic protein post-translational modification (PTM) that plays important roles in regulating enzymatic activity and the pathogenesis of diseases such as atherosclerosis, rheumatoid arthritis, and uremia.
Youngki You, Gina Many, Ernesto S. Nakayasu   +2 more
doaj   +2 more sources

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients [PDF]

BMC Musculoskeletal Disorders, 2017
Background Rheumatoid arthritis (RA) patients carry a high risk of cardiovascular morbidity and mortality. The excess of cardiovascular disease cannot be entirely explained by traditional risk factors and the immune system contributes to the development ...
Francesca Romana Spinelli, Arbi Pecani, Francesco Ciciarello, Tania Colasanti, Manuela Di Franco, Francesca Miranda, Fabrizio Conti, Guido Valesini, Cristiano Alessandri   +8 more
doaj   +3 more sources

Triple positivity for autoantibodies in patients with rheumatoid arthritis is associated with a severe course of the disease but not with bone turnover markers [PDF]

Rheumatology
Introduction Rheumatoid arthritis (RA) is a prevalent autoimmune disorder characterized by chronic joint inflammation and progressive bone erosion. Traditional autoantibodies, such as anti-citrullinated peptide antibodies (ACPAs) and rheumatoid factor ...
Tomasz Budlewski, Joanna Sarnik, Olga Brzezinska, Anna Lewandowska-Polak, Tomasz Poplawski, Joanna Samanta Makowska   +5 more
doaj   +2 more sources

Low mortality rate in Italian rheumatoid arthritis patients from a tertiary center: putative implication of a low anti-carbamylated protein antibodies prevalence [PDF]

Open Access Rheumatology: Research and Reviews, 2018
Daniela Iacono,1 Elvira Favoino,2 Alessia Borgia,1 Serena Fasano,1 Ilenia Pantano,1 Virginia D’Abrosca,1 Giuseppe Picillo,1 Rosa Daniela Grembiale,3 Federico Perosa,2 Gabriele Valentini1 1Department of Clinical and Experimental Medicine ...
Iacono D, Favoino E, Borgia A, Fasano S, Pantano I, D'Abrosca V, Picillo G, Grembiale RD, Perosa F, Valentini G   +9 more
doaj   +2 more sources

Insights into the detection of AMPA cross-reactivity: comparing cyclic peptide- to protein-based assays [PDF]

Arthritis Research & Therapy
Background Autoantibodies targeting antigens carrying distinct post-translational modifications (PTMs), including citrullinated, carbamylated, and acetylated residues, are characteristic for rheumatoid arthritis (RA).
Roxane Biersteker, Aegli Athanasiadou, Stef van der Meulen, Tineke J. van Wesemael, Linda M. Slot, Theresa Kissel, René E. M. Toes, Leendert A. Trouw, Diane van der Woude   +8 more
doaj   +2 more sources