Results 111 to 120 of about 25,158 (228)
Arthritis &Rheumatology, Accepted Article.Objective Mitochondria are organelles with a hypomethylated circular genome. Mitochondrial DNA (mtDNA) in the systemic circulation has been implicated in inflammation. This study investigates the role of circulating DNA in systemic sclerosis (SSc) and the cellular mechanisms governing its release.
Stavros Giaglis +9 more
wiley +1 more source
Erratum to: Different Clinical Relevance of Anti-Citrullinated Protein Antibodies in RA Patients. [PDF]
Dokl Biochem Biophys, 2023 Avdeeva AS, Cherkasova MV, Nasonov EL.
europepmc +1 more source
Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA [PDF]
, 2015 BACKGROUND: Periodontitis (PD) has been reported to be associated with rheumatoid arthritis (RA). Porphyromonas gingivalis (P. gingivalis) is a gram-negative anaerobic bacterium that is recognized as one of the major pathogenic organisms in PD and is the
Eun Bong Lee +7 more
core +1 more source
Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Arthritis &Rheumatology, Accepted Article.Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
Frontiers in Immunology, 2018 Objective: Peptidylarginine deiminases (PAD) 2 and 4 are key enzymes in rheumatoid arthritis (RA) pathogenesis due to their ability to generate the protein targets of anti-citrullinated protein antibodies (ACPA).
Erika Darrah +9 more
doaj +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Evaluate performance of the Predicting Risk of Cardiovascular Disease EVENTs (PREVENT) calculator in rheumatoid arthritis (RA). Methods Patients with RA were matched up to 10 controls on age, sex, and enrollment year using national Veterans Health Administration (VHA), Medicare, and National Death Index data (2006‐2020).
Tate M. Johnson +13 more
wiley +1 more source
Revista Habanera de Ciencias Médicas, 2015 Introducción: la artritis reumatoidea es una enfermedad inflamatoria crónica y multisistémica de causa autoinmune.Los anticuerpos antipéptidos citrulinados constituyen una herramienta importante para el diagnóstico de esta enfermedad.
Goitybell Martínez Téllez +5 more
doaj
Serum Proteomic Signatures of RA Risk and Response: Analysis of the APIPPRA Trial
Arthritis &Rheumatology, Accepted Article.Objective To identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA study participants were selected from baseline to RA onset for 46 RA progressors or to study end for 72 participants who did not develop RA ...
Marianna Jasenecova +9 more
wiley +1 more source
Different Clinical Relevance of Anti-Citrullinated Protein Antibodies in RA Patients. [PDF]
Dokl Biochem Biophys, 2023 Avdeeva AS, Cherkasova MV, Nasonov EL.
europepmc +1 more source
Arthritis &Rheumatology, Accepted Article.Summary Background Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease characterized by clinical and molecular heterogeneity, notably in the presence of anti‐cyclic citrullinated peptide antibodies (CCP). CCP‐positive (CCP+) RA patients exhibit more severe disease progression and distinct treatment responses compared to CCP‐negative (CCP ...
Javad Rahimikollu +10 more
wiley +1 more source