Results 91 to 100 of about 1,448,593 (185)

Comparison of 1064‐nm Picosecond and Q‐Switched Neodymium‐Doped Yttrium Aluminum Garnet Lasers for Melasma in Asian Women: A Randomized Double‐Blind Split‐Face Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Melasma is a chronic, relapsing facial hyperpigmentation that remains challenging to treat in medium‐to‐dark phototypes. Aims To compare the efficacy, safety, tolerability, and recurrence of 1064‐nm picosecond neodymium‐doped yttrium aluminum garnet laser treatment versus 1064‐nm Q‐switched neodymium‐doped yttrium aluminum garnet ...
Ying Wu, Qixuan Wang, Jiayi Feng, Zehua Chen, Lvping Huang, Yongqiang Feng, Xiaojing Li   +6 more
wiley   +1 more source

Efficacy and Safety of L‐Carnosine‐Containing Hyaluronate Injection for Facial Skin Hydration and Brightness: A Randomized, Controlled, Evaluator‐Blinded Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background L‐carnosine, a dipeptide with superior antioxidant and antiglycation properties, serves as the core active component in this study. We aimed to evaluate the efficacy and safety of a novel injectable composite solution, which features L‐carnosine in combination with non‐crosslinked sodium hyaluronate, glycine, alanine, proline, and ...
Zhanhong Li, Jingfang Sun, Zhehu Jin, Wei Guo, Aili Cui, Huaigu Wang, Jiahua Wang, Xiaoyi Qiu, Heyang Xi, Yao Zhang, Lu Zhang, Ligen Xuan, Lingzhi Shi, Yangliang Yi, Huiyin Qiu, Fangke Guan, Yaling Xie, Zhouwei Liu, Lili Liang, Haijun Yang, Chunfang Chen, Huiying Wang, Xiaoling Sun, Fengsheng Che, Qiong Meng   +24 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed, Muhammad Tauseef Sultan, Ahmad Mujtaba Noman, Hassan Raza, Hagar M. Mohamed, Nimra Anees, Muhammad Imran, Muzzamal Hussain, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Entessar Al Jbawi, Ehab M. Mostafa, Samy Selim, Ayman Salama, Mohamed A. Abdelgawad   +14 more
wiley   +1 more source

Neobavaisoflavone Inhibits Melanogenesis through the Regulation of Akt/GSK-3β and MEK/ERK Pathways in B16F10 Cells and a Reconstructed Human 3D Skin Model

Molecules, 2020
Previous studies have confirmed the anti-melanogenic effect of the aerial part of Pueraria lobata, however, due to its inherent color, P. lobata has limited commercial use. In this study, an extract (GALM-DC) of the aerial part of P.
Da Eun Kim, Bo Yoon Chang, Sang Ok Ham, Youn Chul Kim, Sung Yeon Kim   +4 more
doaj   +1 more source

Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

Frontiers in Pharmacology
Background:Sophora flavescens, a traditional Chinese medicine for treating conditions associated with abnormal skin pigmentation, contains flavonoids with inhibitory effects on tyrosinase.
Fenling Fan, Lanqing Chen, Caihong Chen, Song Ang, Justin Gutkowski, Navindra P. Seeram, Hang Ma, Dongli Li, Dongli Li   +8 more
doaj   +1 more source

Skin Boosters: 2026 Updated

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Skin boosters are increasingly used to improve dermal quality through injectable and device‐assisted approaches; however, definitions and clinical evidence remain heterogeneous. Aims To provide an updated overview and propose a practical classification of skin boosters, including mechanisms, delivery methods, clinical outcomes, and limitations.
Kyu‐ho Yi, Hyunggyu Kang, Jong Keun Song, Olena Sydorchuk, Jeremy B. Green, Hugues Cartier, Roya Zarmehr Zamin, Benjamin Ascher   +7 more
wiley   +1 more source

Treatment of Acne‐Induced Facial Post‐Inflammatory Hyperpigmentation With a New 2‐MNG‐Containing Routine Versus a Thiamidol‐Containing Routine—A Monocentric Prospective Double‐Blind Randomized Comparative Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Acne‐induced post‐inflammatory hyperpigmentation (PIHP) is a frequent condition. 2‐mercaptonicotinoyl glycine (2‐MNG) is an innovative anti‐pigmenting molecule. Aims The aim of this study is to compare the efficacy and tolerability of two routines in the treatment of PIHP: 2‐MNG‐containing serum + SPF50+/UVA sunscreen versus ...
Thierry Passeron, Guénaëlle Le Dantec, Samir Salah, Beatrice Marie, Kate Randamy, Kim T. F. C. Dhin‐Kien, Ann' Laure Demessant‐Flavigny, Andrew Alexis   +7 more
wiley   +1 more source

Novel inhibitory function of miR-125b in melanogenesis

, 2013
MicroRNAs are known to be the important regulators of skin physiology and considered as new therapeutic targets to treat skin diseases. In this study, miR-125b was identified as a potent regulator of steady-state melanogenesis.
강효진, 김규한, 유석종
core  

Melanogenesis Inhibitors

, 2018
Abnormally high production of melanin or melanogenesis in skin melanocytes results in hyperpigmentation disorders, such as melasma, senile lentigines or freckles.
Sulekha Kumari, Verma, Navin Kumar, Steven Tien Guan Thng, Navin Kumar Verma, Hemant K. Gautam, Gautam, Hemant K., Thng, Steven Tien Guan, Kumari, Sulekha   +7 more
core   +1 more source

Triterpenoids from the leaves of Osmanthus fragrans var. aurantiacus with their anti-melanogenesis and anti-tyrosinase activities

, 2022
Excessive production of melanin causes various dermatological disorders including hyperpigmentation. To search for anti-melanogenesis candidates from natural products, we discovered that leaves of Osmanthus fragrans var.
Mina Lee (381827), Duc Dat Le (1429312), Ye Eun Lee (10508009)   +2 more
core   +1 more source